Results 41 to 50 of about 1,970,039 (250)
Cardiovascular Research, 2019 Aims Brown fat activation accelerates the uptake of cholesterol-enriched remnants by the liver and thereby lowers plasma cholesterol, consequently protecting against atherosclerosis development. Hepatic cholesterol is then converted into bile acids (BAs)
E. Zhou +14 more
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Adipocyte, 2019 There is increasing evidence that the global rise in temperature is contributing to the onset of diabetes, which could be mediated by a concomitant reduction in brown fat activity.
Michael E. Symonds +4 more
doaj +1 more source
Nature Communications, 2021 Beige and brown fat may influence systemic metabolism through secreted signals. Here the authors identify a panel of metabolites secreted from beige and brown fat cells, which signal to influence fat tissue and skeletal muscle metabolism and have anti ...
Anna Whitehead +19 more
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Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis
bioRxiv, 2019 Brown adipose tissue (BAT) is composed of thermogenic cells that convert chemical energy into heat to help maintain a constant body temperature and counteract metabolic disease in mammals.
Vanja Panic +14 more
semanticscholar +1 more source
Nature Communications, 2018 Increasing brown adipose tissue (BAT) thermogenesis in mice and humans improves metabolic health and understanding BAT function is of interest for novel approaches to counteract obesity.
Elena Schmidt +24 more
semanticscholar +1 more source
Annals of Medicine, 2014 Brown adipose tissue (BAT) is a specialized organ responsible for thermogenesis, a process required for maintaining body temperature. BAT is regulated by the sympathetic nervous system (SNS), which activates lipolysis and mitochondrial uncoupling in brown adipocytes.
Contreras, Cristina +6 more
openaire +5 more sources
Intricate Transcriptional Networks of Classical Brown and Beige Fat Cells
Frontiers in Endocrinology, 2015 Brown adipocytes are a specialized cell type that is critical for adaptive thermogenesis, energy homeostasis and metabolism. In response to cold, both classical brown fat and the newly identified beige or brite cells are activated by β-adrenergic ...
Sean Bong Lee +2 more
doaj +1 more source
Combating Obesity With Thermogenic Fat: Current Challenges and Advancements
Frontiers in Endocrinology, 2020 Brown fat and beige fat are known as thermogenic fat due to their contribution to non-shivering thermogenesis in mammals following cold stimulation. Beige fat is unique due to its origin and its development in white fat.
Ruping Pan +3 more
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Molecular Metabolism, 2021 Objective: Fibroblast growth factor 2 (FGF2) has been reported to play divergent roles in white adipogenic differentiation, however, whether it regulates thermogenesis of fat tissues remains largely unknown.
Haifang Li +11 more
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The hepatokine Tsukushi gates energy expenditure via brown fat sympathetic innervation
Nature Metabolism, 2018 Thermogenesis is an important contributor to whole-body energy expenditure and metabolic homeostasis. Although circulating factors that promote energy expenditure are known, endocrine molecules that suppress energy expenditure have remained largely ...
Qiuyu Wang +12 more
semanticscholar +1 more source