Results 61 to 70 of about 1,970,039 (250)

Near-Infrared Photoluminescent Carbon Nanotubes for Imaging of Brown Fat

open access: yesScientific Reports, 2017
Near-infrared photoluminescent single-walled carbon nanotubes (CNTs) are expected to provide effectual bio-imaging tools, although, as yet, only limited applications have been reported.
M. Yudasaka   +10 more
semanticscholar   +1 more source

Brown Adipogenic Reprogramming Induced by a Small Molecule

open access: yesCell Reports, 2017
Brown adipose tissue (BAT) has attracted considerable research interest because of its therapeutic potential to treat obesity and associated metabolic diseases.
Baoming Nie   +15 more
doaj   +1 more source

Non-invasive quantification of white and brown adipose tissues and liver fat content by computed tomography in mice. [PDF]

open access: yesPLoS ONE, 2012
ObjectivesObesity and its distribution pattern are important factors for the prediction of the onset of diabetes in humans. Since several mouse models are suitable to study the pathophysiology of type 2 diabetes the aim was to validate a novel computed ...
Marko Lubura   +5 more
doaj   +1 more source

The GPR120 agonist TUG‐891 promotes metabolic health by stimulating mitochondrial respiration in brown fat

open access: yesEMBO Molecular Medicine, 2018
Brown adipose tissue (BAT) activation stimulates energy expenditure in human adults, which makes it an attractive target to combat obesity and related disorders.
M. Schilperoort   +17 more
semanticscholar   +1 more source

Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat [PDF]

open access: yesNature, 2013
Maintenance of body temperature is essential for the survival of homeotherms. Brown adipose tissue (BAT) is a specialized fat tissue that is dedicated to thermoregulation. Owing to its remarkable capacity to dissipate stored energy and its demonstrated presence in adult humans, BAT holds great promise for the treatment of obesity and metabolic syndrome.
Schulz, Tim J.   +9 more
openaire   +3 more sources

Transcription regulators and hormones involved in the development of brown fat and white fat browning: transcriptional and hormonal control of brown/beige fat development.

open access: yesPhysiological Research, 2018
The high prevalence of obesity and related metabolic complications has inspired research on adipose tissues. Three kinds of adipose tissues are identified in mammals: brown adipose tissue (BAT), beige or brite adipose tissue and white adipose tissue (WAT)
Jianmei Zhang   +7 more
semanticscholar   +1 more source

Brown fat biology and thermogenesis

open access: yesFrontiers in Bioscience, 2011
Brown fat (brown adipose tissue, BAT) primary function is to produce heat. There is now compelling evidence to indicate that brown fat cells in some BAT depots share their predecessor cells with myocytes. Brown adipocyte (trans)differentiation depends on various receptors / transcription factors that include peroxisome proliferator-activated receptor g
Denis, Richard, Frederic, Picard
openaire   +2 more sources

The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes

open access: yesNature Communications, 2016
The thermogenic activity of brown adipose tissue (BAT) and browning of white adipose tissue are important components of energy expenditure. Here we show that GPR120, a receptor for polyunsaturated fatty acids, promotes brown fat activation. Using RNA-seq
T. Quesada-López   +11 more
semanticscholar   +1 more source

Genetic backgrounds determine brown remodeling of white fat in rodents

open access: yesMolecular Metabolism, 2016
Objective: Genetic background largely contributes to the complexity of metabolic responses and dysfunctions. Induction of brown adipose features in white fat, known as brown remodeling, has been appreciated as a promising strategy to offset the positive ...
Giulia Ferrannini   +7 more
doaj   +1 more source

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