Results 201 to 210 of about 102,830 (343)

A Possible Mechanism: Genistein Improves Metabolism and Induces White Fat Browning Through Modulating Hypothalamic Expression of Ucn3, Depp, and Stc1 [PDF]

, 2019
Liyuan Zhou, Xinhua Xiao, Qian Zhang, Jia Zheng, Ming Li, Mingqun Deng   +5 more
openalex   +1 more source

Biofabrication of Endothelialized, Intrinsically Vascularized 3D‐Printed Recombinant Spider Silk Scaffolds

Advanced Healthcare Materials, EarlyView.
This study evaluates 3D‐printed recombinant spider silk hydrogel eADF4(C16)‐RGD in a rat AV loop model for tissue engineering. Constructs with T17b endothelial progenitor cells showed enhanced vascularization and biodegradation. Results highlight the importance of scaffold design and cellular integration in improving vascular density and overall ...
Claire M. Weinhold, Stefanie Heltmann‐Meyer, Xuen J. Ng, Thomas Scheibel, Tobias Fey, Harald Wajant, Carol Geppert, Andreas Arkudas, Dominik Steiner, Raymund E. Horch   +9 more
wiley   +1 more source

Diels‐Alder Click Chemistry as a Dynamic‐Covalent Crosslinking Method in Spheroid‐Encapsulating Hydrogels for Cartilage Engineering

Advanced Healthcare Materials, EarlyView.
This research shows the development of hydrogels with Diels‐Alder click chemistry for engineering cartilage‐like tissue. The hydrogels support cartilage spheroids which could be cultured for at least 28 days. Furthermore, the spheroids showed a tendency to fuse together into a more consistent construct, and produced important components needed for ...
Sanne M. van de Looij, Antonia G. Vasilopoulou, Lennard Spauwen, Antoinette van den Dikkenberg, Jasmijn V. Korpershoek, Mylene de Ruijter, Jos Malda, Bas G. P. van Ravensteijn, Tina Vermonden   +8 more
wiley   +1 more source

Regulatory effects and mechanisms of exercise on activation of brown adipose tissue (BAT) and browning of white adipose tissue (WAT)

, 2023
Haijun Dong, Man Qin, Peng Wang, Shufan Li, Xing Wang   +4 more
openalex   +1 more source

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

Advanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li, Yu Guan, Nan Song, Feng Zhang, Zhimin Deng, Tailang Yin, Yanbing Yang, João Conde, Wenyi Jin, Zhinang Yin   +9 more
wiley   +1 more source

Effects of Liposome Composition and Size on Protein Corona Formation: Competitive Replacement of Abundant Proteins by High‐Affinity Proteins on the Liposome Surface

Advanced Healthcare Materials, EarlyView.
Coarse‐grained MD simulations capture the effects of liposome composition and size on protein adsorption onto the liposome surface, in agreement with experiments. Liposome‐protein interactions are energetically stabilized by the replacement of abundant proteins with high‐affinity proteins on the liposome surface through electrostatic and hydrophobic ...
Hwankyu Lee
wiley   +1 more source

PTG-Dependent Glycogen Metabolic Dysfunction Drives Impaired Adipose Browning: A Novel Mechanism Linking PM_2.5 to Metabolic Disorders. [PDF]

Adv Sci (Weinh)
Wang L, Hu R, Chai Y, He P, Li S, Zhao L, Zhao W, Zhang L, Qin L, Li R, Hou X, Sun Q, Liu C.   +12 more
europepmc   +1 more source

Study on the Browning Mechanism of Multivitamin Iron Oral Solution Based on Sucrose-Lysine Maillard Reaction [PDF]

Caifeng Su, Jianping Zhu, Zhuangwei Liu, Jie Tan, Jie Jiang, Zhuang Zhao   +5 more
openalex   +1 more source

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

From selection signatures in cattle to functional validation in mice: HSPA12B negatively regulates adipose browning and thermogenesis. [PDF]

J Anim Sci
Gao Y, Wang J, Jiang Q, Wang X, Ju Z, Yang C, Wei X, Zhang Y, Xiao Y, Huang J.   +9 more
europepmc   +1 more source