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Comparison of the mechanism of enzymatic browning in frozen white and brown A. bisporus
European Food Research and Technology, 2018The mechanism of browning in frozen white and brown A. bisporus stored for 8 months at − 25 °C has been determined based on the level of enzymatic activity, free amino acids, total polyphenols, antioxidant activity and color. The brown variety was less resistant than the white variety to enzymatic browning, due to a higher activity of monophenolase and
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The hunt for the molecular mechanism of brown fat thermogenesis
Biochimie, 2017This review focuses on research that my colleagues and I carried out from 1972 to 1986 that led to the identification of the original uncoupling protein and the development of the current model for the acute regulation of brown fat thermogenesis.
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Mechanisms of the anorexia of aging in the Brown Norway rat
Physiology & Behavior, 2006Aging is associated with a loss of the ability to maintain homeostasis in response to physiologic and environmental disturbances. Age-related dysregulation of food intake and energy balance appears to be the result of impaired responsiveness of hypothalamic integrative circuitry to metabolic cues, which can lead to lack of appropriate food intake (the ...
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Mechanical Transmission of Cassava Brown Streak Virus
Nature, 1959BROWN streak virus disease of cassava (Manihot utilissima Pohl.) is important in all the cassava-growing areas on the coasts of Kenya and Tanganyika, because necrosis of the starch storage tissues of the roots and stems of infected plants results in serious losses in yield1,2.
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Control mechanisms in brown adipose tissue plasma membrane
Canadian Journal of Biochemistry and Cell Biology, 1984It is generally agreed that the site of heat production during nonshivering thermogenesis is the brown adipose tissue (BAT) and that the triggering event for heat production is the interaction of noradrenaline (NA) with its receptor on the plasma membrane.
N, Bégin-Heick, H M, Heick
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Mechanism and evolution of the uncoupling protein of brown adipose tissue
Trends in Biochemical Sciences, 1990The uncoupling protein found in mitochondria from thermogenic brown adipose tissue is structurally very similar to two other mitochondrial carrier proteins transporting ADP/ATP and phosphate, respectively. Similarities are also seen with the mechanism of these carriers, which are part of a family of H+/OH(-)-substrate anion co-transporters, further ...
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Mechanisms of thermogenesis in brown adipose tissue
Biochemical Society Transactions, 1986D, Nicholls, S, Cunningham, H, Wiesinger
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Mechanisms of stimulus-calorigenesis coupling in brown adipose tissue
Canadian Journal of Biochemistry and Cell Biology, 1984The sequence of metabolic events leading to increased calorigenesis in brown adipose tissue has been reviewed. The first step of this sequence consists in the binding of norepinephrine to adrenergic receptors of the beta1 subtype. This results in the stimulation of adenylate cyclase and activation of lipolysis via the system of protein kinases ...
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Brown adipose tissue: the molecular mechanism of its formation
Nutrition Reviews, 2009The function of brown adipose tissue (BAT) is to oxidize fat and to dissipate the energy produced as heat, providing a source of heat to the organism. Preadipocytes are stimulated by expression of the PRDM16 gene to differentiate into BAT cells. The PRDM16 protein is greatly enriched in BAT and causes increased expression of mitochondrial genes and ...
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