Results 61 to 70 of about 102,830 (343)

Combination of mesoscale and synoptic mechanisms for triggering an isolated thunderstorm: Observational case study of CSIP IOP 1 [PDF]

, 2007
Copyright @ 2007 AMSAn isolated thunderstorm formed in the southern United Kingdom on 15 June 2005 and moved through the area where a large number of observational instruments were deployed as part of the Convective Storm Initiation Project.
Alan Blyth, Andrew Russell, Bader, Barnes, Bennett, Bishop, Browning, Browning, Burt, Collier, Cullen, Cyril Morcrette, Davies, Done, Fabry, Goddard, Golding, Golding, Gossard, Gossard, Gregory, Hoskins, Humphrey Lean, Hunt, John Nicol, Keith Browning, Lee, Marshall, Morcrette, Nigel Roberts, Orlanski, Peter Clark, Russell, Schmetz, Simpson, Starr   +35 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Transcription Factor E2F1 Knockout Promotes Mice White Adipose Tissue Browning Through Autophagy Inhibition

Frontiers in Physiology, 2021
Obesity is associated with energy metabolic disturbance and is caused by long-term excessive energy storage in white adipose tissue (WAT). The WAT browning potentially reduces excessive energy accumulation, contributing an attractive target to combat ...
Mingchen Xiong, Weijie Hu, Yufang Tan, Honghao Yu, Qi Zhang, Chongru Zhao, Yi Yi, Yichen Wang, Yiping Wu, Min Wu   +9 more
doaj   +1 more source

Role of Z-pinches in magnetic reconnection in space plasmas

, 2014
A widely accepted scenario of magnetic reconnection in collisionless space plasmas is the breakage of magnetic field lines in X-points. In laboratory, reconnection is commonly studied in pinches, current channels embedded into twisted magnetic fields. No
Divin, Andrey, Lapenta, Giovanni, Markidis, Stefano, Olshevsky, Vyacheslav   +3 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Study on the Mechanism of Enzymatic Browning and Its Inhibitors during Lonicera caerulea Fruit Pulp Beating

Shipin gongye ke-ji
In order to solve the enzymatic browning phenomenon in the pulping unit of Lonicera caerulea fruits and improve its utilization value. The main phenolic substrates involved in the enzymatic browning reaction in the pulping process of Lonicera caerulea ...
Yongqiang MA, Dan LI, Qingzhuo XUE, Weiye XIU, Guangzhi LI, Shiyou YU   +5 more
doaj   +1 more source

Three-Dimensional Simulations of Solar and Stellar Dynamos: The Influence of a Tachocline

, 2008
We review recent advances in modeling global-scale convection and dynamo processes with the Anelastic Spherical Harmonic (ASH) code. In particular, we have recently achieved the first global-scale solar convection simulations that exhibit turbulent ...
Miesch, M. S., Browning, M. K., Brun, A. S., Toomre, J., Brown, B. P.   +4 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Comparative Transcriptome and Metabolome Profiling Revealed Molecular Cascade Events During the Enzymatic Browning of Potato Tubers After Cutting

Plants
Enzymatic browning is a major issue in potato processing, causing a decline in both nutritional value and quality. Although there are numerous studies on the mechanism of enzymatic browning of potato tubers, few relevant reports are available on the ...
Li Wang, Jianwei Shan, Jitao Liu, Kang An, Kun Yang, Chengchen Li, Xiaobo Li, Xingyao Xiong   +7 more
doaj   +1 more source

Electron acceleration by cascading reconnection in the solar corona I Magnetic gradient and curvature effects

, 2015
Aims: We investigate the electron acceleration in convective electric fields of cascading magnetic reconnection in a flaring solar corona and show the resulting hard X-ray (HXR) radiation spectra caused by Bremsstrahlung for the coronal source.
Barta, M., Büchner, J., Gan, W., Liu, S., Zhou, X.   +4 more
core   +1 more source