Results 91 to 100 of about 265 (109)

Uncovering the non-histone interactome of the BRPF1 bromodomain using site-specific azide-acetyllysine photochemistry

Journal of Biological Chemistry
Bromodomain-PHD finger protein 1 (BRPF1) belongs to the BRPF family of bromodomain-containing proteins. Bromodomains are exclusive reader modules that recognize and bind acetylated histones and non-histone transcription factors to regulate gene expression.
Soumen Barman, Jyotirmayee Padhan, Babu Sudhamalla   +2 more
openaire   +2 more sources

Brpf1 loss deregulates gene expression important for hippocampus development.

, 2015
(A-C) RT-PCR analysis of transcripts for Brpf1 (A), the acetyltransfrases Hbo1 and hMof (B), and five transcription factors (C), loss of which is known to cause dentate gyrus hypoplasia (see the text). The primers used are listed in S1 Table.
Linya You (700541), Xiang-Jiao Yang (547724), Morag Park (236907), Nicholas R. Bertos (700543), Edwin Wang (24691), Kezhi Yan (700542), Jinfeng Zhou (124013), Hong Zhao (325)   +7 more
core   +1 more source

HIPPOCAMPUS-SPECIFIC LOSS BRPF1 MURINE MODEL EXHIBITS ATTENUATED EXCITATORY SYNAPTIC TRANSMISSION AND IMPAIRED SPATIAL AND FEAR MEMORY

IBRO Neuroscience Reports, 2023
Baicheng Zhao, Hang Zhang, Ying Liu, Linya You   +3 more
doaj   +1 more source

Plenary Abstracts Session & Oral Presentations

HemaSphere, Volume 9, Issue S1, June 2025.
wiley   +1 more source

Looking for BRPF1 Presence in Differentiating Osteoclast Cells [PDF]

, 2019
Through this semester-long experiment, professor Birnbaum and I attempted to identify the presence of BRPF1 (Bromodomain And PHD Finger Containing 1) in harvested RAW osteoclast cells.
Birnbaum, Mark J., Khoury, Nicholas
core  

1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain

, 2015
The BRPF (bromodomain and PHD finger-containing) protein family are important scaffolding proteins for assembly of MYST histone acetyltransferase complexes.
Emmanuel H. Demont (1343475), Emma J. Jones (1343448), Armelle Le Gall (1343469), Jameed Hussain (1343433), Laurie J. Gordon (1343442), Andy D. Roberts (1343439), Peter D. Craggs (1343430), Paola Grandi (1343472), Anne-Marie Michon (1343457), Chun-wa Chung (1343454), Paul Bamborough (1343466), Darren J. Mitchell (1343451), Robert J. Sheppard (1343445), David Fallon (1343460), Rab K. Prinjha (449759), Clare I. Hobbs (1343436), Robert J. Watson (1343463)   +16 more
core   +1 more source

Correction: The Lysine Acetyltransferase Activator Brpf1 Governs Dentate Gyrus Development through Neural Stem Cells and Progenitors. [PDF]

PLoS Genetics, 2015
Linya You, Kezhi Yan, Jinfeng Zou, Hong Zhao, Nicholas R Bertos, Morag Park, Edwin Wang, Xiang-Jiao Yang   +7 more
doaj   +1 more source

Novel BRPF1 mutation in a boy with intellectual disability, coloboma, facial nerve palsy and hypoplasia of the corpus callosum

, 2019
: Mutations in the chromatin regulator gene BRPF1 were recently associated with the Intellectual Developmental Disorder With Dysmorphic Facies And Ptosis (IDDDFP). Up till now, clinical data of 22 patients are reported.
Demeulenaere, Sofie, de Veuster, Ilse, Reyniers, Edwin, Beysen, Diane, Meuwissen, Marije, Kooy, Frank   +5 more
core  

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BRPF2, a novel transcript of BRPF1 and their expression in mice tissues

Hereditas (Beijing), 2013
In order to identify a novel transcript of BRPF1 (BRPF2), a clone separated from mouse cDNA library was sequenced and submitted to GenBank. The expressions of BRPF1 and BRPF2 in different mice tissues were detected using RT-PCR and Northern blotting assays.
Fen GUO, Pi-Rong LIN, Yue-Qin LI, Xian-Li SU, Ding-Ding WANG, Tian-Hong ZHOU   +5 more
openaire   +3 more sources

Abstract 4691: Identification and characterization of BRPF1 bromodomain inhibitors

Cancer Research, 2016
Abstract BRPF (bromodomain and PHD finger-containing) proteins represent a subgroup of the bromodomain protein family with three closely related members, namely BRPF1, -2, and -3. They are found in different histone acetyltransferase complexes and regulate development and cell differentiation.
Bernard Haendler, Léa Bouché, Stephan Siegel, Amaury E. Fernandez-Montalvan, Tatsuo Sugawara, Julia Meier, Stefan Knapp, Vicki Gamble   +7 more
openaire   +1 more source