Results 51 to 60 of about 25,737 (250)

Usefulness of body surface mapping to differentiate patients with Brugada syndrome from patients with asymptomatic Brugada syndrome. [PDF]

, 2004
We attempted to determine the usefulness of body surface mapping (BSM) for differentiating patients with Brugada syndrome (BS) from patients with asymptomatic Brugada syndrome (ABS).
Emori, Tetsuro, Hisamatsu, Kenichi, Kusano, Kengo Fukushima, Matsubara, Hiromi, Morita, Hiroshi, Nagase, Satoshi, Nakamura, Kazufumi, Ohe, Tohru, Takenaka, Shiho   +8 more
core   +1 more source

Brugada Syndrome: New Implications for Heterozygous Carriers of the Pathogenic SCN5A c.689T>C(p.Ile230Thr) Variant

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in the SCN5A gene and its subunits have been identified in individuals with Brugada Syndrome. One such SCN5A variant, c.689T>C(p.Ile230Thr), was previously reported as disease‐causing only in homozygous individuals, with heterozygous carriers being unaffected.
Shayla Shojaat, Benjamin Hale, Taylor Warner   +2 more
wiley   +1 more source

Supraventricular tachyarrhythmia in patients with Brugada syndrome: A single-center study

Journal of Arrhythmia, 2013
Background: Brugada syndrome is a distinct form of idiopathic ventricular fibrillation. We retrospectively investigated the incidence and clinical implications of supraventricular tachyarrhythmia in patients with Brugada syndrome. Methods: We reviewed 69
Kimie Ohkubo, Ichiro Watanabe, Yasuo Okumura, Masayoshi Kofune, Koichi Nagashima, Hiroaki Mano, Kazumasa Sonoda, Toshiko Nakai, Satoshi Kunimoto, Yuji Kasamaki, Atsushi Hirayama, Naokata Sumitomo, Tomohiro Nakayama   +12 more
doaj   +1 more source

Brugada syndrome unmasked by dengue fever

Clinical Case Reports, 2023
Key Clinical Message Understanding the circumstances, leading to unmasking of hidden Brugada syndrome is essential for the practicing clinician and the patients so that they are informed adequately to seek prompt medical attention.
Lokesh Koumar Sivanandam, Hima Bindu R. Basani, Vivek Sanker, Shamal Roshan S, Marah Hunjul, Umang Gupta   +5 more
doaj   +1 more source

Etiological diagnosis, prognostic significance and role of electrophysiological study in patients with Brugada ECG and syncope. [PDF]

, 2017
BACKGROUND: Syncope is considered a risk factor for life-threatening arrhythmias in Brugada patients. Distinguishing a benign syncope from one due to ventricular arrhythmias is often difficult, unless an ECG is recorded during the episode.
Anselmino, M, Barbonaglia, L, Bergamasco, L, Bianchi, F, Bortnik, M, Carvalho, P, Castagno, D, Cerrato, N, Gaita, F, Giustetto, C, Gribaudo, E, Riccardi, R, Rossetti, G, Ruffino, E, Scrocco, C   +14 more
core   +2 more sources

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman, Mathieu Félices, Bhaskar Pandurangavittal, Sanman Ghorpade, Caroline Easterbrook, Marcin Zabielski, Oscar Della Pasqua   +6 more
wiley   +1 more source

Cardiovascular morbidity following epilepsy: A nationwide retrospective cohort study in South Korea

Epilepsia Open, EarlyView.
Abstract Objective This study evaluated the long‐term risk of major cardiovascular diseases (CVDs) in patients with epilepsy using a nationwide cohort, aiming to address critical gaps in population‐based evidence on brain–heart interactions. Methods Data from the Korean National Health Insurance Service (2002–2013) were analyzed.
Youngoh Bae, Chaeyoon Kang, Yejin Lee, Haerim Cho, Hohyun Jung, Seung Won Lee   +5 more
wiley   +1 more source

Brugada syndrome with a novel missense mutation in SCN5A gene: A case report from Bangladesh

Indian Heart Journal, 2014
Brugada syndrome is an inherited cardiac arrhythmia that follows autosomal dominant transmission and can cause sudden death. We report a case of Brugada syndrome in a 55-year-old male patient presented with recurrent palpitation, atypical chest pain and ...
Md. Zahidus Sayeed, Md. Abdus Salam, Md. Zahirul Haque, A.K.M. Monwarul Islam   +3 more
doaj   +1 more source

Role of pharmacotherapy in Brugada syndrome [PDF]

, 2004
In patients who undergo aborted sudden cardiac death or syncope of unknown origin (symptomatic Brugada syndrome), no one argues that the implantation of an ICD is the first-line therapy regardless of the findings of the EP study.
Tsuchiya, Takeshi
core   +1 more source

Clinical and Genetic Significance of Chromosomal Microarray Screening of Asymptomatic Newborns

Journal of Clinical Laboratory Analysis, EarlyView.
Among 99 asymptomatic newborns with abnormal low‐resolution chromosomal microarray (LR‐CMA) screening, 70.7% harbored microduplication/microdeletions with syndromic implications. However, only a minority exhibited developmental concerns during early follow‐up, highlighting the need for cautious interpretation.
Naye Choi, Hwa Young Kim, Jung Min Ko
wiley   +1 more source