Results 81 to 90 of about 1,175 (153)

The Role of Nrf2 in Pancreatic Cancer and the Evaluation of Brusatol as a Chemotherapeutic Agent [PDF]

, 2021
openaire   +1 more source

ADH4 deficiency activates the NRF2-CSF1 axis by increased lipid peroxidation in hepatocellular carcinoma. [PDF]

Cancer Cell Int
Yan P, Luo Y, Peng D, Mou T, Lei D, Li S, Yu H, Huang Z, Wu Z.   +8 more
europepmc   +1 more source

Transcriptomic Analysis Reveals an NRF2-Mediated Redox and Metabolic Reprogramming in Sorafenib-Resistant Hepatocellular Carcinoma Cells. [PDF]

BioTech (Basel)
Michilli A, Bassi C, Moshiri F, De Siena B, Marinaro R, Callegari E, Negrini M, Sabbioni S.   +7 more
europepmc   +1 more source

Effect of Melatonin and Epigallocatechin-3-Gallate Combination on In Vitro Maturation of Mouse Oocytes. [PDF]

Int J Mol Sci
Li S, Chen L, Li Y, Xu L, Chen Y, Ma Y.
europepmc   +1 more source

Activation of the Nrf2/ARE Pathway Attenuates BDE-47-Induced Immunotoxicity in RAW264.7 Macrophages. [PDF]

Biomolecules
Gao Q, Deng Q, Yang Z, Wei L, Chen H.
europepmc   +1 more source

Repositioning Brusatol as a Transmission Blocker of Malaria Parasites:ACS Infectious Diseases

Currently, primaquine is the only malaria transmission-blocking drug recommended by the WHO. Recent efforts have highlighted the importance of discovering new agents that regulate malarial transmission, with particular interest in agents that can be administered in a single low dose, ideally with a discrete and Plasmodium-selective mechanism of action.
Cox, Amelia, Krishnankutty, Neelima, Shave, Steven, Howick, Virginia M., Auer, Manfred, La Clair, James J., Philip, Nisha   +6 more
openaire   +1 more source

Enhancing immunotherapy efficacy of hepatocellular carcinoma by inhibiting the key antioxidant factor Nrf2. [PDF]

Mol Ther Oncol
Zhu Y, Liu M, Kwok HF, Chen L.
europepmc   +1 more source

Nrf2通过上调自噬促进C17.2神经干细胞的增殖

Zhongshan Daxue xuebao. Yixue kexue ban, 2016
摘 要: 【目的】 通过使用化合物调控细胞内信号通路,最终引起脑内神经干细胞的增殖和分化?这被为认为是一种崭新的修复受损大脑功能的治疗策略?我们发现Nrf2能够调控C17.2神经干细胞的增殖,并试图阐明其可能的作用机制?【方法】 采用MTT法检测细胞活力,BrdU掺入法检测细胞增殖,western blot法检测细胞内蛋白水平的变化,流式细胞术检测细胞内ROS水平的变化?【结果】 Nrf2的激动剂t-BHQ和SFN可以促进C17.2神经干细胞的增殖,而使用Nrf2的抑制剂brusatol则抑制其增殖 ...
doaj  

Potential of Traditional Chinese Medicine <i>Brucea javanica</i> in Cancer Treatment: A Review of Chemical Constituents, Pharmacology, and Clinical Applications. [PDF]

Nutrients
Xu W, Yang H, Zhou Y, Guo R, Liu J, Wei F, Lin Y.   +6 more
europepmc   +1 more source

Targeted inhibition of Nrf2 potentiates antitumor immunity and enhances the efficacy of immunotherapy in hepatocellular carcinoma. [PDF]

J Immunother Cancer
Zhu Y, Liu M, Fan X, Xu Y, Diao X, Bi J, Wan X, Assaraf YG, Kwok HF, Chen L.   +9 more
europepmc   +1 more source