Advancements in Buccal Drug Delivery: Polymers and Their Applications
RGUHS Journal of Pharmaceutical SciencesBuccal drug delivery offers a promising alternative to conventional oral routes by facilitating the rapid and efficient absorption of therapeutics directly through the mucosal tissues lining the oral cavity.
Shardor Ambarish G +2 more
doaj +2 more sources
In Vitro Evaluation of 2D-Printed Edible Films for the Buccal Delivery of Diclofenac Sodium. [PDF]
Materials (Basel), 2018 Printing technologies have recently emerged in the development of novel drug delivery systems toward personalized medicine, to improve the performance of formulations, existing bioavailability patterns, and patients’ compliance.
Eleftheriadis GK +3 more
europepmc +2 more sources
Buccal and sublingual vaccine delivery
Journal of Controlled Release, 2014 Because of their large surface area and immunological competence, mucosal tissues are attractive administration and target sites for vaccination. An important characteristic of mucosal vaccination is its ability to elicit local immune responses, which act against infection at the site of pathogen entry. However, mucosal surfaces are endowed with potent
Heleen Kraan +5 more
openalex +5 more sources
Buccal Absorption of Biopharmaceutics Classification System III Drugs: Formulation Approaches and Mechanistic Insights [PDF]
PharmaceuticsBuccal drug delivery emerges as a promising strategy to enhance the absorption of drugs classified under the Biopharmaceutics Classification System (BCS) Class III, characterized by high solubility and low permeability. However, addressing the absorption
Rayan Sabra +4 more
doaj +2 more sources
Formulation of Carbopol®/Poly(2-ethyl-2-oxazoline)s Mucoadhesive Tablets for Buccal Delivery of Hydrocortisone. [PDF]
Polymers (Basel), 2018 Poly(2-ethyl-2-oxazoline) has become an excellent alternative to the use of poly(ethylene glycol) in pharmaceutical formulations due to its valuable physicochemical and biological properties. This work presents a formulation of poorly-water soluble drug,
Ruiz-Rubio L +5 more
europepmc +2 more sources
Phospholipid Deformable Vesicles for Buccal Delivery of Insulin.
Chemical and Pharmaceutical Bulletin, 2002 To investigate the possibility of the enhancing effect of deformable vesicles on buccal delivery of insulin, two kinds of vesicles with and without the presence of sodium deoxycholate (deformable vesicles and conventional vesicles) were prepared by reverse phase evaporation methods.
Tian-zhi Yang +3 more
openalex +5 more sources
Development and Optimization of Chitosan-Ascorbate-Based Mucoadhesive Films for Buccal Delivery of Captopril. [PDF]
PharmaceuticsPamlényi K +7 more
europepmc +2 more sources
Bioavailability Enhancement and Formulation Technologies of Oral Mucosal Dosage Forms: A Review [PDF]
PharmaceuticsThe oral mucosa is a versatile surface for drug administration, supporting both local and systemic therapies. Many active substances are effectively absorbed in the oral cavity, offering an alternative to enteral administration by bypassing the harsh ...
Ildikó Bácskay +10 more
doaj +2 more sources
Synthesis of Poly (2-hydroxyethyl ethyleneimine) and Its Mucoadhesive Film Formulations When Blended with Chitosan for Buccal Delivery of Haloperidol. [PDF]
Macromol BiosciSoradech S +2 more
europepmc +2 more sources
Lidocaine loaded gelatin/gelatinized tapioca starch films for buccal delivery and the irritancy evaluation using chick chorioallantoic membrane. [PDF]
Saudi Pharm J, 2019 Wannaphatchaiyong S +4 more
europepmc +2 more sources