Results 11 to 20 of about 2,886,007 (195)
BUCCAL DRUG DELIVERY: A TECHNICAL APPROACH [PDF]
Journal of Drug Delivery and Therapeutics, 2012 Over the last few years Pharmaceutical scientists are trying to explore transdermal and transmucosal routes as an alternative to injections. Buccal delivery of the desired drug using mucoadhesive polymers has been the subject of interest since the early 1980s.
Y Mamatha +4 more
openaire +3 more sources
Sublingual and Buccal Delivery: A Historical and Scientific Prescriptive
PharmaceuticsIn this review, our intention was to shed some light on the history of sublingual and buccal delivery over the past 75 years. By searching the query sublingual and buccal, we noticed four steady growth periods in the number of publications between 1950 ...
Sina Bahraminejad, Hassan Almoazen
doaj +2 more sources
Bioadhesive polymers, permeation enhancers and types of dosage forms for buccal drug delivery [PDF]
, 2021 The buccal delivery is defined as the drug administration through the mucosal membranes lining the cheeks (buccal mucosa). The main impediment to the use of many hydrophilic macromolecular drugs as potential therapeutic agents is their inadequate and ...
Satla, Shobha Rani +2 more
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Formulation and Evaluation of Biopolymer Based Buccal Film of Diclofenac Sodium
Journal of Basic and Applied Research in Biomedicine, 2022 Buccal drug delivery gives easier and safe method of drug administration because in case of toxicity it can be terminated by simply removing the dosage form from buccal cavity.
Pooja Kashid +2 more
doaj +2 more sources
Gels, 2022 Carvedilol (CRV) is a non-selective third generation beta-blocker used to treat hypertension, congestive heart failure and angina pectoris. Oral administration of CRV showed poor bioavailability (25%), which might be ascribed to its extensive first-pass ...
El-Sayed Khafagy +13 more
doaj +1 more source
Aerosil in Solid-state Buccal Film for Improved and Sustained Delivery of Valsartan: Molecular Docking Studies [PDF]
Chemical and Biochemical Engineering Quarterly, 2023 To overcome low oral bioavailability and short biological half-life, improved and sustained buccal delivery of valsartan has been proposed. Valsartan film with colloidal silicon dioxide has been prepared using HPMC as mucoadhesive polymer matrix by ...
R. Swain +5 more
doaj +1 more source
Release of functional dexamethasone by intracellular enzymes: A modular peptide-based strategy for ocular drug delivery [PDF]
, 2020 Tissue barriers limit drug delivery in the eye. Therefore, retinal diseases are treated with intravitreal injections. Delivery systems with reduced dosing frequency and/or cellular drug delivery properties are needed.
Sadeghi, Amir +7 more
core +1 more source
Pharmaceutics, 2023 Injectable peptides such as insulin, glucagon-like peptide 1 (GLP-1), and their agonists are being increasingly used for the treatment of diabetes. Currently, the most common route of administration is injection, which is linked to patient discomfort as ...
Anubhav Pratap-Singh +3 more
doaj +1 more source
Chitosan based hydrogels for transmucosal drug delivery [PDF]
, 2013 The aim of this thesis was the formulation of new chitosan based delivery systems for transmucosal drug administration. Transmucosal routes, such as buccal, vaginal and nasal routes, allow the circumvention of the hepatic first pass metabolism and avoid ...
Abruzzo, Angela <1984>
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Preface for buccal drug delivery theme issue [PDF]
, 2014 During the past years, buccal drug delivery has attracted the attention of researchers looking for alternative delivery routes of administration. As an alternative to oral drug delivery, the buccal mucosal route avoids the passage through the acidic ...
Morales, Javier Octavio +3 more
core +1 more source