Results 31 to 40 of about 2,886,007 (195)

Development, Characterization, and Ex Vivo Assessment of Elastic Liposomes for Enhancing the Buccal Delivery of Insulin

, 2021
Buccal drug delivery is a suitable alternative to invasive routes of drug administration. The buccal administration of insulin for the management of diabetes has received substantial attention worldwide.
Sangkil Lee, Gyubin Noh, Santosh Bashyal, Shrawani Lamichhane, Jo-Eun Seo, Taekwang Keum   +5 more
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Ovalbumin and cholera toxin delivery to buccal mucus for immunization using microneedles and comparison of immunological response to transmucosal delivery

, 2021
The oral mucosa is an effective site for vaccination. However, for oral mucosal vaccines, delivery of the right dose of vaccine is not possible due to the water-rich environment.
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Preparation of Diphenhydramine Hydrochloride Mucoadhesive Oral Film and the Evaluation of its Pharmaceutics characteristics [PDF]

Journal of Fasa University of Medical Sciences, 2015
Background & Objective: In recent years, mucoadhesive drug delivery systems has shown interested for prolonging the residence time of the dosage form and for providing a controlled rate of drug release.
Rahim Bahri Najafi, Dena Monzavi
doaj   +1 more source

Advancements in Buccal Drug Delivery: Polymers and Their Applications

RGUHS Journal of Pharmaceutical Sciences
Buccal drug delivery offers a promising alternative to conventional oral routes by facilitating the rapid and efficient absorption of therapeutics directly through the mucosal tissues lining the oral cavity.
Shardor Ambarish G, Siddramappa B Shirsand, Anand Kumar Yegnoor   +2 more
doaj   +1 more source

Formulation and Physicochemical Characterization of Buccoadhesive Microspheres Containing Diclofenac Sodium

Advanced Pharmaceutical Bulletin, 2014
Purpose: The present study involves preparation and evaluation of diclofenac buccal-mucoadhesive microparticles for prolongation of buccal residence time. Methods: The microparticles were prepared by modified double-emulsion dehydration method (O1/W/O2)
Mitra Jelvehgari, Hadi Valizadeh, Ramin Jalali Motlagh, Hassan Montazam   +3 more
doaj   +1 more source

Nano-based drug delivery systems: Conventional drug delivery routes, recent developments and future prospects

Medicine in Drug Discovery, 2022
Drug delivery can be defined as the group of approaches a drug or pharmacologically active agent can be transported to the target cell to treat disease or health issue.
Afreen Sultana, Mina Zare, Vinoy Thomas, T.S. Sampath Kumar, Seeram Ramakrishna   +4 more
doaj   +1 more source

Buccal Mucosa: a Gifted Choice for Systemic Drug Delivery [PDF]

, 2011
The main aim of pharmaceutical research is steadily shifted from the development of new chemical entities to the development of novel drug delivery system of existing drug molecule to maximize their effectiveness in terms of therapeutic action, patent ...
G. Parthasarathy, K. Bhaskar, K.N Jayaveera, Prasanth V.V   +3 more
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Self-Nano-Emulsifying Drug-Delivery Systems: From the Development to the Current Applications and Challenges in Oral Drug Delivery.

, 2020
Approximately one third of newly discovered drug molecules show insufficient water solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems (SNEDDSs) are one of the emerging strategies developed to tackle the issues
Beloqui Garcia, Ana, Memvanga, Patrick, Aristote B. Buya, Véronique Préat, Buya, Aristote Banzenga, Ana Beloqui, Préat, Véronique, Patrick B. Memvanga   +7 more
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Boosting buccal drug absorption: Mechanistic insights into bilosome-mediated delivery

International Journal of Pharmaceutics: X
Effective buccal drug delivery is limited by the barrier properties of the mucosa, necessitating innovative systems to enhance permeability without compromising tissue integrity.
Eleftheria Pantazoglou, Scarlett Zeiringer, Matteo Tollemeto, Nazanin Zanjanizadeh Ezazi, Zhongyang Zhang, Leticia Hosta-Rigau, Jette Jacobsen, Ramona Jeitler, Eva Roblegg, Line Hagner Nielsen   +9 more
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Buccal Absorption of Biopharmaceutics Classification System III Drugs: Formulation Approaches and Mechanistic Insights

Pharmaceutics
Buccal drug delivery emerges as a promising strategy to enhance the absorption of drugs classified under the Biopharmaceutics Classification System (BCS) Class III, characterized by high solubility and low permeability. However, addressing the absorption
Rayan Sabra, Daniel Kirby, Vikram Chouk, Kleta Malgorzata, Afzal R. Mohammed   +4 more
doaj   +1 more source