Results 71 to 80 of about 2,886,007 (195)

Chitosan-based mucoadhesive patches for buccal delivery of olmesartan in hypertension treatment

Journal of Applied Pharmaceutical Research
Background: Delivering poorly soluble drugs like Olmesartan (OMS) effectively remains a key challenge due to low oral bioavailability and extensive first-pass metabolism.
Ram Nikhate, Sanjay Patil
doaj   +1 more source

Lidocaine loaded gelatin/gelatinized tapioca starch films for buccal delivery and the irritancy evaluation using chick chorioallantoic membrane

Saudi Pharmaceutical Journal, 2019
The aim of this study was to confirm the feasibility of gelatin/gelatinized tapioca starch (α st) films for buccal delivery and to evaluate their irritancy. Lidocaine (LB) and lidocaine hydrochloride (LH) were used as model drugs and glycerin was used as
Suchipha Wannaphatchaiyong, Paul Wan Sia Heng, Jirapornchai Suksaeree, Prapaporn Boonme, Wiwat Pichayakorn   +4 more
doaj   +1 more source

The Interplay between Drug and Sorbitol Contents Determines the Mechanical and Swelling Properties of Potential Rice Starch Films for Buccal Drug Delivery. [PDF]

Polymers (Basel), 2021
Alrimawi BH, Chan MY, Ooi XY, Chan SY, Goh CF.   +4 more
europepmc   +1 more source

Superparamagnetic Iron Oxide Nanoparticles Encapsulated in Biodegradable Thermosensitive Polymeric Micelles: Toward a Targeted Nanomedicine Suitable for Image-Guided Drug Delivery [PDF]

, 2009
Superparamagnetic iron oxide nanoparticles (SPIONs) have been receiving great attention lately due to their various biomedical applications, such as in MR imaging and image guided drug delivery.
Seevinck, P.R., Talelli, M., Dep Farmaceutische wetenschappen, van Nostrum, C.F., Rijcken, C.J.F., Lammers, T., Storm, G., Hennink, W.E., Advanced drug delivery systems/drug targeting   +8 more
core  

Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]

, 2014
Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G., Conway, Barbara, Kakadia, Partibha   +3 more
core   +1 more source

APPROACHES OF BUCCAL DRUG DELIVERY SYSTEM

, 2020
Buccal drug delivery leads direct access to the systemic circulation through the internal jugular vein by passes drugs from the hepatic first pass metabolism leading to high bioavailability. Buccal route is an attractive route of administration for systemic drug delivery.
openaire   +2 more sources

Reduction-sensitive polymers and bioconjugates for biomedical applications [PDF]

, 2009
Reduction-sensitive biodegradable polymers and conjugates have emerged as a fascinating class of biomedical materials that can be elegantly applied for intracellular triggered gene and drug delivery.
Meng, F.H., Zhong, Z., Dep Farmaceutische wetenschappen, Hennink, W.E., Advanced drug delivery systems/drug targeting   +4 more
core  

Mechanisms of deformable nanovesicles based on insulin-phospholipid complex for enhancing buccal delivery of insulin

International Journal of Nanomedicine, 2018
You Xu,1,2 Xing Zhang,1,2 Yun Zhang,1,2 Jun Ye,1,2 Hong-Liang Wang,1,2 Xuejun Xia,1,2 Yuling Liu1,2 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & ...
Xu Y, Zhang X, Zhang Y, Ye J, Wang HL, Xia X, Liu Y   +6 more
doaj  

Development, in-vitro and ex-vivo evaluation of HPMC E-15/Xanthan gum mucoadhesive buccal patch of telmisartan

Journal of Applied Pharmaceutical Research
Background: Telmisartan, an antihypertensive drug, exhibits poor aqueous solubility and low oral bioavailability due to extensive hepatic first-pass metabolism.
Hattaraki Shashank Shivanand, Preethi G.B, Shashank K, Subham Roy, Suhasini Rendale   +4 more
doaj   +1 more source

Advances in Buccal Films: A Promising Platform for Oral Mucosal Drug Delivery: An updated review

The buccal route offers a non-invasive method for drug administration that improves systemic absorption by bypassing hepatic first-pass metabolism. This article summarises recent innovations, including the incorporation of nanoparticles and 3D printing ...
Shahidulla , S.M., Khan , Zubair, Imtiyaz , Mohammed   +2 more
core   +1 more source