Results 81 to 90 of about 2,886,007 (195)

Mucoadhesive polymer films for tissue retraction in laparoscopic surgery : ex-vivo study on their mechanical properties [PDF]

open access: yes, 2014
This work was financially supported by the Engineering and Physical Sciences Research Council (EPSRC), UK, under Grant EP/H010033/1 and the Royal Society (GJF).Safe and effective manipulation of soft tissue during laparoscopic procedures can be achieved ...
Florence, Gordon John   +10 more
core   +1 more source

The processes of reform in Victoria’s alcohol and other drug sector, 2011-2014 [PDF]

open access: yes, 2014
This paper explores issues and concerns related to the 2014 alcohol and other drug sector recommissioning process in Victoria. Overview In mid-2014, the Victorian Alcohol and Drug Association approached the Drug Policy Modelling Program, at the ...
Drug Policy Modelling Program
core  

Polymeric films for buccal drug delivery [PDF]

open access: yes, 2009
The aim of this research project is to evaluate whether or not pullulan films are suitable to buccal drug delivery of a phosphodiesterase5 (PDE5) inhibitor yonkenafil, which was discovered in our research group and currently is under phase II clinical trial for treatment of erectile dysfunction. Variable formulations of pullulan films were designed and
openaire   +1 more source

Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer–based drug delivery systems [PDF]

open access: yes, 2006
The direct intratumoral (i.t.) injection of anticancer agents has been evaluated extensively in the past few decades. Thus far, however, it has failed to become established as an alternative route of administration in routine clinical practice.
Ulbrich, K.   +9 more
core   +1 more source

BUCCAL DRUG DELIVERY SYSTEM: A REVIEW

open access: yes
Drug delivery through the buccal route has become common due to its numerous benefits, including bypassing first – pass metabolism, which enhances the bioavailability of the drug and decreases the quantity of the drug required. Furthermore, drugs with a high molecular weight that cannot be administered via the oral route can be administered using the ...
*Shweta Manoj Dhule   +5 more
openaire   +2 more sources

Development of polymer-bound fast-dissolving metformin buccal film with disintegrants

open access: yesInternational Journal of Nanomedicine, 2015
Shaikh Ershadul Haque, Angappan Sheela Materials Chemistry Division, Centre for Nanomaterials, School of Advanced Sciences, VIT University, Vellore, India Abstract: Fast-dissolving drug-delivery systems are considered advantageous over the existing ...
Haque SE, Sheela A
doaj  

Development of transfersomal buccal patches of galantamine for enhanced bioavailability in Alzheimer’s disease therapy

open access: yesJournal of Applied Pharmaceutical Research
Background: Galantamine, an acetylcholinesterase inhibitor used in Alzheimer’s disease, exhibits low and variable bioavailability due to gastrointestinal metabolism and first-pass hepatic elimination. Buccal drug delivery offers a non-invasive route that
Pavuluri Chandrasekhar   +1 more
doaj   +1 more source

Facilitated Buccal Insulin Delivery via Hydrophobic Ion-Pairing Approach: In vitro and ex vivo Evaluation

open access: yesInternational Journal of Nanomedicine, 2021
Santosh Bashyal,1 Jo-Eun Seo,1 Taekwang Keum,1,2 Gyubin Noh,1,2 Shrawani Lamichhane,1,2 Jeong Hwan Kim,1,2 Chang Hyun Kim,3 Young Wook Choi,3 Sangkil Lee1,2 1College of Pharmacy, Keimyung University, Daegu, Republic of Korea; 2Center for Forensic ...
Bashyal S   +8 more
doaj  

Evaluating the role of amino acids and isothermal dry particle coating in modulating buccal permeation of large molecule drug vancomycin

open access: yesScientific Reports
The formulation and delivery of macromolecules through the oral route pose considerable challenges due to factors such as large molecular weight, pH sensitivity, and limited formulation approaches.
Anthony Rajabi   +6 more
doaj   +1 more source

Review On Buccal Drug Delivery

open access: yes
The oral route is favored for drug administration. However, in the case of various drugs, physiological and biochemical reasons make it difficult to achieve an acceptable level of absorption. Other routes like parenteral administration also have limitations.
openaire   +1 more source

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