Results 111 to 120 of about 148,168 (309)

HtrA3 stromal expression is correlated with tumor budding in stage II colorectal cancer. [PDF]

, 2017
Tumor budding is a well-established adverse prognostic factor in colorectal carcinoma (CRC). It may represent a form of epithelial-to-mesenchymal transition (EMT), although the underlying mechanisms remain unclear. High-temperature requirement A3 (HtrA3)
Erin Kennedy, Naziheh Assarzadegan, Kennedy, Erin, Messenger, David E, Karagiannis, George S, Richard Kirsch, Mahdi Rahimi, Heather Dawson, George S. Karagiannis, Forse, Catherine L, David E. Messenger, Eleftherios P. Diamandis, Dawson, Heather, Brenda O'Connor, Catherine L. Forse, Andrea Grin, O'Connor, Brenda, Riddell, Robert H, Robert H. Riddell, Kirsch, Richard, Diamandis, Eleftherios P, Assarzadegan, Naziheh, Grin, Andrea, Rahimi, Mahdi   +23 more
core   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source

Budding and explosive membrane vesicle production by hypervesiculating Escherichia coli strain ΔrodZ

Frontiers in Microbiology
Escherichia coli produces extracellular vesicles called outer membrane vesicles. In this study, we investigated the mechanism underlying the hypervesiculation of deletion mutant ΔrodZ of E. coli.
Yoshihiro Ojima, Kaho Toda, Tomomi Sawabe, Yuki Kumazoe, Yuhei O. Tahara, Makoto Miyata, Masayuki Azuma   +6 more
doaj   +1 more source

Geomag Mimetic Dynamically Reconfigurable POSS Framework Enables Antifatigue Solid Electrolyte Interphases for Lithium Metal Anodes

Advanced Science, EarlyView.
A Geomag‐inspired dynamically reconfigurable POSS framework is constructed to form an antifatigue solid electrolyte interphase (SEI) for lithium metal anodes. The rigid POSS nanocages and reversible hydrogen‐bonded junctions enable adaptive stress dissipation and stable Li+ transport during repeated plating/stripping, thereby suppressing dendrite ...
Tianyi Wang, Wei Gu, Yu Liu, Di He, Zairan Xiao, Zixia Lin, Tao Huang, Jiabao Li, Hui Chong, Yaojie Lei, Xiaobo Zheng, Bing Sun, Guoxiu Wang, Chengyin Wang   +13 more
wiley   +1 more source

HIV Pol inhibits HIV budding and mediates the severe budding defect of Gag-Pol. [PDF]

, 2012
The prevailing hypothesis of HIV budding posits that the viral Gag protein drives budding, and that the Gag p6 peptide plays an essential role by recruiting host-cell budding factors to sites of HIV assembly. HIV also expresses a second Gag protein, p160
Stephen J Gould, Xin Gan
core   +1 more source

A Study on cocoa (Theobroma cacao L.) budding V. The influence of rootstocks on scion-yield quality

Coffee and Cocoa Research Journal, 1990
Tulisan ini merupakan kelanjutan hasil penelitian yang telah ditulis sebelumnya. Analisis mutu biji dilaksanakan pada panenan umur 7 tahun. Hasilnya menunjukkan bahwa batang bawah kakao tidak berpengaruh nyata pada mutu fisik maupun mutu kimiawi hasil
Adi Prawoto
doaj   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

Advanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang, Mengmeng Li, Xuehui Dai, Yanchen Zhang, Yuhan Wu, Zhaotao Yan, Chenfei Tian, Hongkai Fan, Haili Liu, Xiaowei Zhang, Yiming Yang, Jiayu Lu, Yuwei Sun, Yong Wang   +13 more
wiley   +1 more source

Antiviral Functions of Monoclonal Antibodies against Chikungunya Virus

Viruses, 2019
Chikungunya virus (CHIKV) is the most common alphavirus infecting humans worldwide. Antibodies play pivotal roles in the immune response to infection. Increasingly, therapeutic antibodies are becoming important for protection from pathogen infection for ...
Jing Jin, Graham Simmons
doaj   +1 more source

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

Advanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding, Huiying Chen, Yuyu Jiang, Chunyan Zhao, Jie Bai, Yan Xiang, Zeting Wang, Xixi Wang, Bing Rui, Wanda Tang, Yue Ding, Zhenzhen Zhan, Yunkai Zhang, Xingguang Liu   +13 more
wiley   +1 more source

Natural Variation of COLD and CATECHINS REGULATOR 1 Coordinately Fine‐Tunes Cold Tolerance and Tea Quality in Tea Plants

Advanced Science, EarlyView.
Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang, Wei Tong, Qiong Wu, Didi Wu, Yanrui Zhang, Qijuan Gao, Fangdong Li, Zhaoliang Zhang, Wenjie Wang, Chuankui Song, Enhua Xia   +10 more
wiley   +1 more source