Results 11 to 20 of about 58,384 (313)

Biophysical and chemical stability of surfactant/budesonide and the pulmonary distribution following intra-tracheal administration

open access: yesDrug Delivery, 2019
Intra-tracheal instillation of budesonide using surfactant as a vehicle significantly decreased the incidence of bronchopulmonary dysplasia or death in preterm infants.
Chung-Ming Chen   +4 more
doaj   +2 more sources

Intranasal Application of Budesonide Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Suppressing Nucleotide-Binding Oligomerization Domain-Like Receptor Family, Pyrin Domain-Containing 3 Inflammasome Activation in Mice

open access: yesJournal of Immunology Research, 2019
Aim. To investigate the protective effects of budesonide against lipopolysaccharide- (LPS-) induced acute lung injury (ALI) in a murine model and its underlying mechanism. Methods. Adult male C57BL/6 mice were divided into three groups: control, ALI, and
Liang Dong   +8 more
doaj   +2 more sources

Oral Fluvoxamine With Inhaled Budesonide for Treatment of Early-Onset COVID-19

open access: yesAnnals of Internal Medicine, 2023
Previous trials have shown the effects of fluvoxamine alone and inhaled budesonide alone for prevention of disease progression among outpatients with COVID-19. This placebo-controlled, randomized trial, conducted at 12 clinical sites in Brazil, sought to
Gilmar Reis   +34 more
semanticscholar   +1 more source

Budesonide as first-line treatment in patients with autoimmune hepatitis seems inferior to standard predniso(lo)ne administration

open access: yesHepatology, 2023
Background and Aims: In patients with non-severe acute or chronic autoimmune hepatitis (AIH) without cirrhosis, clinical practice guidelines recommend indistinct use of prednisone or budesonide.
Á. Díaz‐González   +27 more
semanticscholar   +1 more source

Current knowledge of targeted-release budesonide in immunoglobulin A nephropathy: A comprehensive review

open access: yesFrontiers in Immunology, 2023
Immunoglobulin A (IgA) nephropathy is a common autoimmune kidney disease. Accumulating studies showed that IgA nephropathy may be partially correlated with mucosal immune system dysfunction.
Jian-An Liao   +9 more
semanticscholar   +1 more source

Albuterol-Budesonide Fixed-Dose Combination Rescue Inhaler for Asthma.

open access: yesNew England Journal of Medicine, 2022
BACKGROUND As asthma symptoms worsen, patients typically rely on short-acting β2-agonist (SABA) rescue therapy, but SABAs do not address worsening inflammation, which leaves patients at risk for severe asthma exacerbations.
A. Papi   +11 more
semanticscholar   +1 more source

Budesonide Maintenance in Microscopic Colitis: Clinical Outcomes and Safety Profile From a Population-Based Study

open access: yesAmerican Journal of Gastroenterology, 2022
INTRODUCTION: Outcomes and safety of budesonide maintenance therapy in microscopic colitis (MC) are not well known. METHODS: Adult residents of Olmsted County, Minnesota, diagnosed with MC (2002–2019) and treated with budesonide were identified using the
June Tome   +6 more
semanticscholar   +1 more source

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

open access: yesHepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole   +12 more
wiley   +1 more source

Inhaled budesonide for COVID-19 in people at higher risk of adverse outcomes in the community: interim analyses from the PRINCIPLE trial

open access: yesmedRxiv, 2021
BACKGROUND Inhaled budesonide has shown efficacy for treating COVID-19 in the community but has not yet been tested in effectiveness trials. METHODS We performed a multicenter, open-label, multi-arm, adaptive platform randomized controlled trial ...
Ly-Mee Yu   +23 more
semanticscholar   +1 more source

Budesonide/Glycopyrronium/Formoterol: A Review in COPD

open access: yesDrugs, 2021
Budesonide/glycopyrronium/formoterol (BREZTRI AEROSPHERE™; TRIXEO AEROSPHERE™) is an inhaled fixed-dose combination of the inhaled corticosteroid (ICS) budesonide, the long-acting muscarinic antagonist (LAMA) glycopyrronium bromide and the long-acting β2-
Young-A. Heo
semanticscholar   +1 more source

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