Results 61 to 70 of about 3,231 (233)
Bufadienolides from the Venom of and Their Enzyme Inhibition Activities and Brine Shrimp Lethality
Natural Product Communications, 2018 A new bufadienolide named dyscinobufotalin ( 1 ), along with twenty known bufadienolides ( 2–21 ) were isolated from the venom of Bufo bufo gargarizans . Their structures were elucidated by spectroscopic analysis.
Jian Xiao +8 more
doaj +1 more source
Onderstepoort Journal of Veterinary Research, 2005 Poisoning with cardiac glycoside-containing plants is collectively the most important plant-associated poisoning of livestock in southern Africa. As a diagnosis of this significant poisoning is currently based on circumstantial evidence, a practical ...
R.A. Schultz +2 more
doaj +1 more source
Senyawa Bufadienolida Yang Bersifat Insektisida, Daigremontianin Dari Daun Cocor Bebek (Kalanchoe Daigremontiana) [PDF]
, 2011 Dalam penelitian berkelanjutan untuk pencarian senyawa-senyawa yang bersifat insektisida daritanaman Kalanchoe (Cocor bebek) Indonesia, diperoleh hasil bahwa ekstrak metanol daun Cocorbebek (Kalanchoe daigremontiana) memberikan aktivitas insektisida yang
Huspa, D. H. (Desi) +4 more
core
International Journal of Oncology, 2018 Glioblastoma is the most common and lethal intracranial tumor type, characterized by high angiogenic and infiltrative capacities. To provide a novel insight into therapeutic strategies against glioblastoma, the cytotoxicity of arenobufagin and ...
Lingyu Han +7 more
semanticscholar +1 more source
Potential Health Risks Posed by Plant-Derived Cumulative Neurotoxic Bufadienolides in South Africa
Molecules, 2016 Bufadienolide-type cardiac glycosides have a worldwide distribution and are mainly synthesized by plants, but there are also animal sources. In South Africa, members of three genera of the Crassulaceae (Cotyledon, Tylecodon and Kalanchoe) cause a unique ...
Christo Botha
doaj +1 more source
A new bufadienolide from Bufo gargarizans Cantor
Natural Product ResearchBufo gargarizans Cantor (B. gargarizans) is the most widely distributed and abundant species of toad in China. Bufadienolides and indole alkaloids have cardiotonic and anti-tumor activities and are important pharmacological components of B.
Li-Jie Zhu +4 more
semanticscholar +1 more source
RSC Advances, 2019 The population of Bufo bufo gargarizans Cantor in China has been alarmingly declining due to environmental pollution. Deltamethrin is a pyrethroid pesticide frequently used in agriculture and much of its residues are present in crops, soil and water ...
Jing Zhou +8 more
semanticscholar +1 more source
VIEW, Volume 7, Issue 2, April 2026.This review explores how mass spectrometry is transforming research in natural medicines, with Traditional Chinese medicine (TCM) as a primary exemplar. It details the application of advanced mass spectrometry in chemical analysis, the development of comprehensive quality control methods, and systematic research on the targeted mechanisms of single ...
Yudian Xu +7 more
wiley +1 more source
Combinatorial chemistry in toad: a protoxin self-resistance way to its own bufadienolide toxin
, 2020 1. Toxin resistance in all taxa is important for their survival. Resistance to bufadienolide toxin is mediated by molecular changes to the sodium-potassium-pump.
Denglang Zou +5 more
semanticscholar +1 more source
Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications
Experimental Physiology, Volume 111, Issue 3, Page 653-673, 1 March 2026.Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó +1 more
wiley +1 more source