Results 81 to 90 of about 3,231 (233)
Chemical Defense of an Asian Snake Reflects Local Availability of Toxic Prey and Hatchling Diet [PDF]
, 2012 Species that sequester toxins from prey for their own defense against predators may exhibit population-level variation in their chemical arsenal that reflects the availability of chemically defended prey in their habitat.
Burghardt, G. M. +6 more
core +2 more sources
Bufadienolides from Drimia robusta BAK [PDF]
Scientia Pharmaceutica, 2000 From bulbs of Drimia robusta 7 bufadienolides were isolated, 3 of them new natural compounds. Structure elucidation was performed by comparison with authentic substances or by means of 1H-, 13C-NMR-spectroscopy and FAB-MS. The substances were identified as scilliroside (1), 12ß-hydroxyscillirosidin (2), 12ß-hydroxyscilliroside (3), hellebrigenin-3-0-ß ...
Krenn, L., Stapf, V., Kopp, B.
openaire +2 more sources
Bufalin‐Induced Epithelial‐to‐Mesenchymal Transition in Kidney Epithelial Cells
Cell Biology International, Volume 49, Issue 12, Page 1764-1786, December 2025.ABSTRACT The kidney plays a central role in fluid, electrolyte, and blood pressure regulation, processes tightly coupled to Na⁺/K⁺‐ATPase activity. Beyond its canonical transport function, Na⁺/K⁺‐ATPase also acts as a signaling receptor for cardiotonic steroids (CTSs) such as bufalin, which have been implicated in fibrosis and epithelial‐to‐mesenchymal
Gabriela Morais de Oliveira Barros +3 more
wiley +1 more source
Frontiers in Pharmacology, 2019 Bufotalin (BFT), one of the naturally occurring bufodienolides, has multiple pharmacological and toxicological effects including antitumor activity and cardiotoxicity.
Zi-Ru Dai +12 more
doaj +1 more source
A Comparison of Adrenal in Toad-Eating and Nontoad-Eating Snakes [PDF]
, 2011 Toads are chemically defended by bufadienolides, a class of cardiotonic steroids lethal to most predators, including many snakes. Bufadienolides bind to Na+K +-ATPase, inhibiting their ability to transport ions.
Mohammadi, Shabnam
core +2 more sources
Journal of Cellular and Molecular Medicine, Volume 29, Issue 11, June 2025.ABSTRACT Nasopharyngeal carcinoma (NPC) is a unique cancer type originating from the nasopharynx. To investigate novel strategies for improving prognosis and reducing the adverse effects of current treatments, this study examined the efficacy of hellebrigenin.
Hsin‐Yu Ho +6 more
wiley +1 more source
Basic &Clinical Pharmacology &Toxicology, Volume 136, Issue 5, May 2025.USP13 is a promising therapeutic target for cellular proliferation in multiple myeloma. Bruceine A can retard the development of multiple myeloma by targeting USP13/PARP1‐mediated DNA damage repair and triggering cell apoptosis. ABSTRACT Multiple myeloma (MM) is an incurable hematologic malignancy, driving significant interest in the discovery of novel
Mengjie Guo +9 more
wiley +1 more source
Molecules, 2019 In order to evaluate the quality of Bufonis Venenum commercial herbs, a three-step qualitative and quantitative research study was performed. Firstly, we tried to identify small molecules and peptides in Bufonis Venenum using pre-fractionation ...
Rongrong He +11 more
doaj +1 more source
Bioactive Ingredients of L. (Christmas Rose): The Renaissance of an Old Medicinal Herb—A Review
Natural Product Communications, 2023 The medicinal plant Helleborus ni g er L. (Ranunculaceae) found in the European Alps has been valued as an effective remedy for numerous diseases for centuries. Recent preclinical evaluations showed pharmacologic potential of the plant extract for cancer
Eckehard Cuny
doaj +1 more source
Mucinaea (Hyacinthaceae-Urgineoideae), a Remarkable New Genus from Namaqualand (Northern Cape Province, South Africa) [PDF]
, 2013 We here describe a new genus from Namaqualand, which is based on Tenicroa nana Snijman. Mucinaea M. Pinter, Mart.-Azorín, U. Müll.-Doblies, D. Müll.- Doblies, Pfosser & Wetschnig gen. nov.
Crespo, Manuel B. +8 more
core +1 more source