Cardiac Glycoside 3β-Bufalin Suppresses Cancer Cell Proliferation by Coupling with Na<sup>+</sup>,K<sup>+</sup>-ATPase and Volume-Regulated Anion Channel Within Membrane Microdomains. [PDF]
Fujii T +6 more
europepmc +1 more source
Bufalin Suppresses Pancreatic Ductal Adenocarcinoma Through ER Stress-Ferroptosis Crosstalk Associated with IP<sub>3</sub>R-Linked Ca<sup>2+</sup> Dysregulation and ATF3/SLC7A11 Regulation. [PDF]
Yang PW +7 more
europepmc +1 more source
Corrigendum to "Immediate tumor killing and long-term anti-tumor immunoreaction induced by Bufalin-loaded phototherapeutic Janus membrane in CRC postoperative therapy" [Mater. Today Bio 37 (2026) 102824]. [PDF]
Yu X +8 more
europepmc +1 more source
Pharmacological Effects of Natural Products: Antioxidant, Anti-Inflammatory and Anticancer Activities. [PDF]
Sepúlveda-Arias JC, Robles-Zepeda RE.
europepmc +1 more source
MAGEC2 promotes tumorigenesis in multiple myeloma through USP16-mediated deubiquitination and stabilization of c-Myc. [PDF]
Liu Z +8 more
europepmc +1 more source
A narrative review of cinobufacini for endometrial cancer: mechanisms and therapeutic implications. [PDF]
Xu L.
europepmc +1 more source
Synthesis of bufalin derivatives with inhibitory activity against prostate cancer cells
Bufalin possesses a strong anti-cancer effect, but the cardiac toxicity targeting the Na+, K+-ATPase limits its application. Here, two bufalin derivatives, bufadienolactam (1) and secobufalinamide (2), were synthesised by treating bufalin with ammonium ...
Jin, Lu +10 more
core
Bufalin: a potential drug for regulating EGFR-TKIs resistance in lung cancer via the EGFR-PI3K/Akt-mTOR signaling. [PDF]
Bai Y +6 more
europepmc +1 more source
Derivatization of Bufadienolides at Carbon-3 of the Steroid Core and Their Consequences for the Interaction with Na<sup>+</sup>,K<sup>+</sup>-ATPase. [PDF]
Ladefoged LK, Schiøtt B, Fedosova NU.
europepmc +1 more source
Functional characterization of 3β-hydroxysteroid dehydrogenases in Asiatic toad reveals an efficient broad substrate specificity of Bg-3βHSD2. [PDF]
Meng Q +8 more
europepmc +1 more source

