Results 111 to 120 of about 559,515 (356)

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Reconfigurable buffer mechanism in switch fabric design

open access: yesTongxin xuebao, 2012
Current research focused on the theoretic buffer size of routers.The reconfigurable buffer tried to improve the buffer utilization rate to optimize the system performance based on the on-demand design of the reconfigurable system.In fact,for current ...
Hui-qun HUANG   +3 more
doaj   +2 more sources

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Evaluating vegetated buffer zones for phosphorus retention in cereal and grass production [PDF]

open access: yes, 2008
The buffer zones seem to be effective to stop erosion and trap particle bound P in surface runoff from the autumn ploughed clay soil. On pastures, the buffers are not so important, if P fertiliser is not surface applied and the grazing intensity is not ...
Uusi-Kämppä, Jaana
core  

Buffer Management Algorithms in Unbounded Buffers

open access: yesJournal of information and communication convergence engineering, 2010
In a network router, packet loss may occur when it overflows due to sudden burst traffic. This paper studies how much large buffers are required to eliminate the packet losses. There are buffers on which packets arrive and one output port to which a packet is transmitted at a time.
openaire   +3 more sources

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Neighborhood-based PA and its environmental correlates: a GIS- and GPS based cross-sectional study in the Netherlands

open access: yesBMC Public Health, 2018
Background To improve our understanding of the neighborhood environment – physical activity (PA) relationship, it is of importance to assess associations between neighborhood environmental characteristics and neighborhood-based PA. Methods Participants’ (
Marijke Jansen   +4 more
doaj   +1 more source

Advanced exploitation of buffer overflow [PDF]

open access: yesarXiv, 2004
This article describes in depth several ways of exploiting buffer overflows in the UNIX operating systems.
arxiv  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Detrimental effect of zwitterionic buffers on lysosomal homeostasis in cell lines and iPSC-derived neurons [version 1; peer review: 3 approved]

open access: yesAMRC Open Research, 2020
Good’s buffers are commonly used for cell culture and, although developed to have minimal to no biological impact, they cause alterations in cellular processes such as autophagy and lysosomal enzyme activity. Using Chinese hamster ovary cells and induced
Nicholas D. Allen   +8 more
doaj  

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