Results 91 to 100 of about 663,058 (303)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Resilience-based design of a tall building. Case-study.
Revista ALCONPATThis paper presents the assessment of performance of a case-study tall building in quantitative manner in terms of structural and nonstructural components damage, repair cost and repair time, following methodology mentioned in FEMA P-58, precursor ...
Thaung Htut Aung, Mir Shabir Ali Talpur
doaj +1 more source
Building confidence in the Dirac δ -function
European Journal of Physics, 2018 8 pages, 3 ...
Asim Gangopadhyaya, Constantin Rasinariu
openaire +4 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Function Assistant: A Tool for NL Querying of APIs
, 2017 In this paper, we describe Function Assistant, a lightweight Python-based toolkit for querying and exploring source code repositories using natural language.
Kuhn, Jonas, Richardson, Kyle
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Art in The Midst Of Enviromental Conflict: On Tisna Sanjaya’s IBU Cigondewah [PDF]
, 2019 In this paper, author will examine the work of artist Tisna Sanjaya titled IMAH BUDAYA (IBU) CIGONDEWAH) / CIGONDEWAH CULTURAL CENTER. Created in 2011, this work can be regarded as one of the breakthroughs done by Tisna Sanjaya as an artist. By posing as
Yeru, A. I. (Aulia)
core