Results 51 to 60 of about 439,953 (245)
A method for metropolitan landscape characterization; case study Rotterdam
Spool, 2014 This paper presents a theoretical and methodological framework for a comprehensive landscape characterization, focussing on the largest and most complex urban realm: the metropolitan region.
Alexandra Tisma +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A completely transparent, adhesively bonded soda-lime glass block masonry system
Journal of Facade Design and Engineering, 2015 A pioneering, all transparent, self-supporting glass block facade is presented in this paper. Previously realized examples utilize embedded metal components in order to obtain the desired structural performance despite the fact that these elements ...
Faidra Oikonomopoulou +3 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Kine-Mould: Flexible mould system opens up wide range of possibilities
Spool, 2014 The Kine-Mould is a development that makes it easier to manufacture building elements with complex geometry. Since June 2014 the team has been working on a range of solutions and prototypes.
Roel Schipper +14 more
doaj +3 more sources
International Journal of Built Environment and Sustainability, 2015 Malaysia is currently enjoying an overhang of housing supply. The focus is gradually shifting from providing just a mere shelter to something more socially.
Tareef Hayat Khan +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
ISPRS International Journal of Geo-InformationThis study explores the reuse of high-resolution 3D spatial datasets for multiple urban analyses within a game engine environment, aligning with circular economy principles in sustainable urban planning. The work is situated in two residential test areas
Heikki Kauhanen +6 more
doaj +1 more source
Rethinking Space Design Standards Toward Quality Affordable Housing In Malaysia
MATEC Web of Conferences, 2016 Provision of affordable housing is important to low- and middle-income population. A fit form of house will not only fulfil a basic human need for shelter, but it also contributes to physical and psychological well-being of the occupants.
Ishak Nor Haniza +3 more
doaj +1 more source