Results 61 to 70 of about 1,026 (172)

Genotypes of Hepatitis B and D Viruses Among Patients With Hepatitis D in the United States

open access: yesJournal of Viral Hepatitis, Volume 33, Issue 7, July 2026.
ABSTRACT The epidemiological landscape of paired hepatitis B virus (HBV)/hepatitis delta virus (HDV) genotype (GT) among patients with HDV in the US remains unknown. HBV/HDV genotypes were assessed in two independent US cohorts: Cohort 1 included 5222 HBV‐positive patients from Quest Diagnostics, including 114 anti‐HDV+ patients; Cohort 2 included 178 ...
Andrew Lopez   +17 more
wiley   +1 more source

Long-Term Strategies for Poorly Water-Soluble Peptides: Combining Fatty Acid Modification with PAS Fusion

open access: yes, 2023
Bulevirtide, an entry inhibitor for the hepatitis B virus (HBV) and hepatitis D virus (HDV), is currently available on the European market. However, its clinical application is constrained by its short half-life and poor water solubility, rendering it ...
Haoju Hua (17535590)   +7 more
core   +1 more source

Liver Transplantation for HBV‐Related Disease in France: NUC Type Before LT Is Associated With Patient Survival

open access: yesLiver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background & Aims Liver transplantation (LT) is indicated for liver complications related to hepatitis B virus (HBV) infection: acute liver failure (ALF), decompensated cirrhosis or hepatocellular carcinoma (HCC). The present study aimed to describe and evaluate patient survival after LT for HBV‐related disease in France and identify the ...
Isaure Bienvenue   +28 more
wiley   +1 more source

Bulevirtide monotherapy for 48 weeks in patients with HDV-related compensated cirrhosis and clinically significant portal hypertension

open access: yes, 2022
Background & aims: Bulevirtide (BLV) has recently been conditionally approved for the treatment of chronic hepatitis delta (CHD) in Europe, but its effectiveness and safety in patients with compensated cirrhosis and clinically significant portal ...
Scholtes C   +29 more
core   +1 more source

Dried Blood Spot: A Tool to Ensure Broad Access to Hepatitis D Screening, Diagnosis, and Treatment Monitoring

open access: yesLiver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background and Aims Chronic hepatitis D is the most severe form of viral hepatitis. Despite recommendations for systematic screening of HBsAg‐positive individuals, hepatitis D infection remains underdiagnosed. Standard HDV virological markers are classically assessed in serum or plasma specimens obtained through venous whole blood sampling ...
Rola Matar   +10 more
wiley   +1 more source

Modern aspects of anti-viral therapy for hepatitis D

open access: yesЖурнал инфектологии
Viral hepatitis D (HDV infection) worsens the prognosis of HBV infection course in 80-90% of cases, accelerating fibrosis and leading to liver cirrhosis or hepatocellular carcinoma. Hepatitis D affects at least 125 000 people in Russia, and in the world,
A. S. Zheleznova   +2 more
doaj   +1 more source

Toward a Functional Cure for Chronic Hepatitis B: Current Landscape and Future Directions in Japan

open access: yesHepatology Research, Volume 56, Issue 6, Page 903-913, June 2026.
Hepatitis B is a viral liver infection that can become chronic, increasing the risk of developing liver cancer and liver failure. Because current treatments rarely cure these problems, researchers are now focusing on a functional cure in which the virus becomes undetectable in blood and stays that way, even after the treatment ends.
Yutaka Handa   +2 more
wiley   +1 more source

Review article: clinical pharmacology of current and investigational hepatitis B virus therapies

open access: yes, 2020
Contains fulltext : 218239.pdf (Publisher’s version ) (Closed access)BACKGROUND: Treatment of hepatitis B virus (HBV) infection with current therapy suppresses HBV DNA, but loss of hepatitis B surface antigen (HBsAg; functional cure ...
Burger, D.M.   +7 more
core   +1 more source

Improving Virological Monitoring of HDV Infection: A Proof-of-Concept Comparative Study of Bosphore and AltoStar® Assays in Patients Treated with Bulevirtide

open access: yesBiomedicines
Hepatitis delta virus (HDV) infection is associated with severe hepatic complications and rapid progression towards liver cirrhosis and hepatocellular carcinoma. Accurate measurement of HDV RNA is critical for monitoring therapeutic responses, especially
Verdiana Zulian   +10 more
doaj   +1 more source

Nationwide Implementation of Double Reflex Testing for Hepatitis Delta in Spain: Results From the Retrospective Phase of the Spain‐DDR Study

open access: yesAlimentary Pharmacology &Therapeutics, Volume 63, Issue 10, Page 1390-1397, May 2026.
Nationwide implementation of double reflex testing for hepatitis delta in Spain markedly increased anti‐HDV and HDV viral load testing between 2022 and 2024, enabling national seroprevalence estimates. Despite this progress, substantial regional heterogeneity persists, highlighting the need for standardised reflex diagnostic protocols.
Ana Alberola   +95 more
wiley   +1 more source

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