Results 101 to 110 of about 6,633 (239)

Spatiotemporal Analysis of Guaroa Virus Diversity, Evolution, and Spread in South America

Emerging Infectious Diseases, 2015
We conducted phylogeographic modeling to determine the introduction and spread of Guaroa virus in South America. The results suggest a recent introduction of this virus into regions of Peru and Bolivia over the past 60–70 years and emphasize the need for
Allison Groseth, Kurt R. Wollenberg, Veena Mampilli, Taylor Shupert, Carla Weisend, Carolina Guevara, Tadeusz J. Kochel, Robert B. Tesh, Hideki Ebihara   +8 more
doaj   +1 more source

Crimean-Congo Hemorrhagic Fever Virus for Clinicians—Epidemiology, Clinical Manifestations, and Prevention

Emerging Infectious Diseases
Crimean-Congo hemorrhagic fever (CCHF) is a tickborne infection that can range from asymptomatic to fatal and has been described in >30 countries. Early identification and isolation of patients with suspected or confirmed CCHF and the use of appropriate
Maria G. Frank, Gretchen Weaver, Vanessa Raabe   +2 more
doaj   +1 more source

Tamdy virus pathogenesis in immunocompetent and immunocompromised mouse models

Virulence
Tamdy virus (TAMV) is one of the zoonotic tick-borne bunyaviruses that have emerged as global public health threats in recent decades. To date, however, TAMV pathogenesis remains poorly understood.
Mingxue Cui, Hua-Chen Zhu, Xiurong Wang, Ying Cao, Di Liu, Michael J. Carr, Yi Guan, Hong Zhou, Weifeng Shi   +8 more
doaj   +1 more source

RNA Encapsidation and Packaging in the Phleboviruses

Viruses, 2016
The Bunyaviridae represents the largest family of segmented RNA viruses, which infect a staggering diversity of plants, animals, and insects. Within the family Bunyaviridae, the Phlebovirus genus includes several important human and animal pathogens ...
Katherine E. Hornak, Jean-Marc Lanchy, J. Stephen Lodmell   +2 more
doaj   +1 more source

Severe fever with thrombocytopenia syndrome in children: a case report [PDF]

, 2014
BACKGROUND: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by a novel bunyavirus (SFTSV) in China. Humans of all ages living in endemic areas have high risk of acquiring SFTS.
Hong-Yu Wang, Li-Yuan Wang, Ning Cui, Qing-Bin Lu, Wei Liu, Wu-Chun Cao, Ying Wo   +6 more
core   +2 more sources

Viral RNA Silencing Suppression: The Enigma of Bunyavirus NSs Proteins

Viruses, 2016
The Bunyaviridae is a family of arboviruses including both plant- and vertebrate-infecting representatives. The Tospovirus genus accommodates plant-infecting bunyaviruses, which not only replicate in their plant host, but also in their insect thrips ...
Marcio Hedil, Richard Kormelink
doaj   +1 more source

Development of FRET-based cap-snatching endonuclease assay

Microbiology Spectrum
The order Bunyavirales consists of over 300 species of segmented, negative-strand RNA viruses. These viruses have a tri-segmented genome (S, M, and L segments) that encodes the nucleocapsid protein (N protein), glycoprotein precursor, and RNA-dependent ...
Jeeva Subbiah, Austin Royster, Sheema Mir, Mohammad Mir   +3 more
doaj   +1 more source

Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

mBio, 2019
Crimean-Congo hemorrhagic fever virus (CCHFV) infection can result in a severe hemorrhagic syndrome for which there are no antiviral interventions available to date. Certain RNA viruses, such as CCHFV, encode cysteine proteases of the ovarian tumor (OTU)
Florine E. M. Scholte, Brian L. Hua, Jessica R. Spengler, John V. Dzimianski, JoAnn D. Coleman-McCray, Stephen R. Welch, Laura K. McMullan, Stuart T. Nichol, Scott D. Pegan, Christina F. Spiropoulou, Éric Bergeron   +10 more
doaj   +1 more source

Oropouche Virus (OROV): Expanding Threats, Shifting Patterns, and the Urgent Need for Collaborative Research in Latin America

Viruses
Recent outbreaks of Oropouche virus (OROV) in Latin America demonstrate shifting epidemiological trends, with increasing clinical severity and geographic expansion driven by environmental and anthropogenic factors, many of which remain uncertain.
André Ricardo Ribas Freitas, David A. Schwartz, Antônio Silva Lima Neto, Rosana Rodrigues, Luciano Pamplona Goes Cavalcanti, Pedro María Alarcón-Elbal   +5 more
doaj   +1 more source

IRF-5-dependent signaling restricts Orthobunyavirus dissemination to the central nervous system [PDF]

, 2015
Interferon (IFN)-regulatory factor 5 (IRF-5) is a transcription factor that induces inflammatory responses after engagement and signaling by pattern recognition receptors.
Diamond, Michael S, Gorman, Matthew J, Hyde, Jennifer L, Lazear, Helen M, Lucas, Tiffany, Pinto, Amelia K, Proenca-Modena, Jose Luiz, Richner, Justin M, Sesti-Costa, Renata   +8 more
core   +3 more sources