Results 231 to 240 of about 104,116 (405)

Urgent Need for Pairing Training and Education With Fentanyl Test Strip Distribution

open access: yesDrug and Alcohol Review, EarlyView.
ABSTRACT Introduction Fentanyl test strips (FTS) are increasingly recommended for non‐heroin drugs to detect potential fentanyl adulteration. The aim of this study was to better understand how people are using FTS. Methods In simulation exercises between September and October 2023, 40 people who used drugs participated in a mock use of FTS on a ...
Megan K. Reed   +5 more
wiley   +1 more source

Evaluation of leptin treatment on maintenance of body weight loss in diet‐induced obese mice

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To evaluate the therapeutic potential of leptin treatment for weight loss maintenance preclinically, through a systematic evaluation of leptin efficacy (a) following a period of weight loss stability (as in published clinical studies), and (b) across a range of circulating leptin concentrations achieved through a variety of different ...
Danna M. Breen   +9 more
wiley   +1 more source

Development of a preclinical testing platform for clinically relevant therapy for Dravet syndrome

open access: yesEpilepsia, EarlyView.
Abstract Objective Patients with drug‐resistant epilepsy, including Dravet syndrome, are frequently prescribed multiple antiseizure medications. Nevertheless, people with Dravet syndrome often have inadequate seizure control, and there is an ongoing unmet clinical need to identify novel therapeutics.
Jeffrey A. Mensah   +7 more
wiley   +1 more source

Systemic administration of analgesic buprenorphine, but not carprofen, affects cardiomyocyte contractility in rodents. [PDF]

open access: yesJ Mol Cell Cardiol Plus
Duursma I   +5 more
europepmc   +1 more source

Buprenorphine

open access: bronze, 1991
Richard Ginsburg, Maurice Lippmann
openalex   +1 more source

Chronic behavioral and seizure outcomes following experimental traumatic brain injury and comorbid Klebsiella pneumoniae lung infection in mice

open access: yesEpilepsia, EarlyView.
Abstract Objective Traumatic brain injury (TBI) is a leading cause of long‐term disability, and infections such as pneumonia represent a common and serious complication for patients with TBI in the acute and subacute post‐injury period. Although the acute effects of infections have been documented, their long‐term consequences on neurological and ...
Sarah S. J. Rewell   +9 more
wiley   +1 more source

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