Results 91 to 100 of about 18,506 (177)

Optimization of high-dose busulfan dosing in bone marrow transplant patients

, 1996
Objective. To review the pharmacokinetics profile of (HD-BU) high-dose busulfan, review published phar macodynamic relationships of high-dose busulfan and discuss clinical considerations of monitoring patients receiving high-dose busulfan. Data Sources.
Cheryl Tate, James S. Partyka
core   +1 more source

Potential Benefit of Ruxolitinib in Suspected Ocular and Neurological Transplant‐Associated Thrombotic Microangiopathy After Allogeneic Stem Cell Transplantation: A Case Report and Review

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT We describe a rare case of suspected delayed‐onset TA‐TMA with ocular and neurological involvement following allo‐HSCT. The condition was refractory to standard therapies; neurological improvement was temporally associated with ruxolitinib initiation, suggesting a possible GVHD overlap.
Lise‐Marie Pillet, Antoine Arandilla, Gaëtan Sauvetre, Paul Goupillou, Adrien Lefevre, Maximilien Grall, Antoine Bonnevalle, Bertrand Bourre, Dominique Penther, Sophie Porcheron, Fabrice Jardin, Mustafa Alani, Sydney Dubois, Vincent Camus   +13 more
wiley   +1 more source

Total body irradiation is associated with increased burden of cerebral microbleeds in haematopoietic stem cell transplant recipients

British Journal of Haematology, EarlyView.
Jure Hederih, Asad Charania, Camelia Vladescu, Ira Lacej, Richard Szydlo, Jiri Pavlu, Renuka Palanicawandar, Jose Ros‐Soto, Andrew Innes, Dragana Milojkovic, Eduardo Olavarria, Jane Apperley, Adam Waldman, Nichola Cooper   +13 more
wiley   +1 more source

Allogeneic Hematopoietic Stem Cell Transplantation Achieves Durable Remission in Blast‐Phase Chronic Myeloid Leukemia Presenting as Early T‐Cell Precursor Acute Lymphoblastic Leukemia

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Introduction The presentation of chronic myeloid leukemia (CML) in the blast phase as early T‐cell precursor acute lymphoblastic leukemia (ETP‐ALL) is very rare. As previously reported, in contrast to B‐ALL, the prognosis is poor. Case Presentation We encountered a patient with blast phase CML presenting as ETP‐ALL.
Takafumi Tsushima, Yukiko Konishi, Natsumi Yoda, Koichiro Wada, Kento Okamoto, Kosuke Matsuo, Shuntaro Isogai, Sonoko Shimoji, Yoshikazu Utsu, Shin‐Ichi Masuda, Nobuyuki Aotsuka   +10 more
wiley   +1 more source

Busulfan 12 mg/kg plus melphalan 140 mg/m2 versus melphalan 200 mg/m2 as conditioning regimens for autologous transplantation in newly diagnosed multiple myeloma patients included in the PETHEMA/GEM2000 study

Haematologica, 2010
Background The aim of this study was to compare the long-term safety and efficacy of oral busulfan 12 mg/kg plus melphalan 140 mg/m2 and melphalan 200 mg/m2 as conditioning regimens for autologous stem cell transplantation in newly diagnosed patients ...
Juan José Lahuerta, Maria Victoria Mateos, Joaquin Martínez-López, Carlos Grande, Javier de la Rubia, Laura Rosiñol, Anna Sureda, José García-Laraña, Joaquín Díaz-Mediavilla, Miguel T. Hernández-García, Dolores Carrera, Joan Besalduch, Felipe de Arriba, Albert Oriol, Lourdes Escoda, Javier García-Frade, Concepción Rivas-González, Adrían Alegre, Joan Bladé, Jesús F. San Miguel   +19 more
doaj   +1 more source

Expanded Umbilical Cord Blood Transplantation in Cerebral X‐Linked Adrenoleukodystrophy: A Case Report

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Umbilical cord blood transplantation is a viable source of stem cells due to accessibility and low incidence of chronic graft‐versus‐host disease despite human‐leukocyte‐antigen mismatching. Disadvantages of low stem cell dose in larger recipients include delayed immune reconstitution, graft rejection, and mortality.
Rachel E. Granberg, Thomas Pfeiffer, Sanil Sansar, Rafael Galindo, Shalini Shenoy   +4 more
wiley   +1 more source

Post‐Transplant Bendamustine as a Platform for Immune Modulation After Allogeneic Hematopoietic Cell Transplantation

European Journal of Haematology, Volume 117, Issue 4, Page 739-749, October 2026.
ABSTRACT Post‐transplant cyclophosphamide (PT‐CY) remains the standard of care for graft‐versus‐host disease (GvHD) prophylaxis in haploidentical hematopoietic cell transplantation (HCT), yet relapse, delayed immune reconstitution, infections, and organ toxicity represent persistent and clinically meaningful limitations.
Megan J. Cracchiolo, Richard J. Simpson, Emmanuel Katsanis   +2 more
wiley   +1 more source

The Preconditioning of Busulfan Promotes Efficiency of Human CD133+ Cells Engraftment in NOD Shi-SCID IL2Rγcnull (NOG) Mice via Intra-Bone Marrow Injection

Cell Transplantation, 2019
Human CD133 + stem cells were injected into the bone marrow cavity of NOG (NOD Shi-SCID IL2Rγc null ) mice with or without preconditioning of busulfan in order to assess the efficiency of human CD133 + cells engraftment.
Xiaofang Guo, Xiaoxiao Yin, Wenjuan Zhu, Ying Pan, Hui Wang, Yinming Liang, Xiaofei Zhu   +6 more
doaj   +1 more source

Early Acute Kidney Injury in Allogeneic Hematopoietic Cell Transplantation: Incidence, Severity, and Associated Factors in a 634‐Recipient Cohort

European Journal of Haematology, Volume 117, Issue 4, Page 981-994, October 2026.
ABSTRACT Background Acute kidney injury (AKI) is a frequent and clinically relevant complication in allogeneic hematopoietic cell transplantation (HCT) recipients, particularly during the early post‐HCT period. Although AKI has been extensively reported in long‐term follow‐up studies, data focusing on the initial hospitalization phase remain limited ...
Luiz Carlos da Costa‐Junior, Rita de Cássia Barbosa da Silva Tavares, Marina Izu, Simone Cunha Maradei, Maria Claudia Rodrigues Moreira, Marta Colares Nogueira, Décio Lerner, Fabrício Guimarães Bino, Patrícia Moriel, Teresa de Souza Fernandez, Paulo Caleb Júnior Lima Santos   +10 more
wiley   +1 more source

HEPATOPROTECTIVE EFFECT OF Physalis angulata L. LEAF ETHANOL EXTRACT AGAINST BUSULFAN-INDUCED LIVER DAMAGE IN FEMALE RATS

Biotropia: The Southeast Asian Journal of Tropical Biology
ARTICLE HIGLIGHTS Busulfan can damage the liver by triggering oxidative stress  Physalis angulata leaves show natural liver protective effects  Extract reduced oxidative damage in liver tissue  Liver structure improved after extract treatment  Early ...
Elsi Rahmadhani, Aryani Sismin Satyaningtijas, Damiana Rita Ekastuti, Ronald Tarigan, I Ketut Mudite Adnyane, Kusdiantoro Mohamad, Wahono Esthi Prasetyaningtyas, Yanti Sulistyana   +7 more
doaj   +1 more source