Results 81 to 90 of about 18,506 (177)

Successful allo‐hematopoietic stem cell transplantation using washed hematopoietic stem cells in a pediatric patient complicated by acute myeloid leukemia and severe anaphylaxis to blood product

Pediatric Investigation, EarlyView.
Jieyu Tian, Guanghua Zhu, Maoquan Qin, Chenguang Jia, Shuxuan Ma, Bin Wang, Yanhui Luo   +6 more
wiley   +1 more source

A retrospective study of treosulfan versus busulfan‐based conditioning in pediatric patients

, 2022
20.500.12530/87857To compare the outcomes of treosulfan-based vs busulfan-based conditioning regimens in allogeneic hematopoietic stem cell transplantation (HSCT) in pediatric patients.
Casado-Abad, Gema, Olivas-Mazón, Raquel, Bueno, David, Raquel Olivas‐Mazón, Luisa Sisinni, Sisinni, Luisa, Gema Casado‐Abad, Mozo, Yasmina, David Bueno, Yasmina Mozo, Antonio Pérez Martínez, Martínez, Antonio Pérez   +11 more
core   +1 more source

KRAS Mutations Predict Inferior Post‐Remission Outcomes in Newly Diagnosed Acute Myeloid Leukemia With MAPK Pathway Mutations

European Journal of Haematology, EarlyView.
ABSTRACT Somatic mutations in the MAPK signaling pathway are frequently identified at AML diagnosis; however, their impact on treatment resistance and long‐term survival remains unclear. We conducted a retrospective study of patients with newly diagnosed MAPK‐mutated AML seen at the University of Iowa Health Care.
Kensuke Takaoka, Sarah Mott, Ratdanai Yodsuwan, Sakditad Saowapa, Manasawee Tanariyakul, Chalothorn Wannaphut, Kittika Poonsombudlert   +6 more
wiley   +1 more source

Busulfan inhibits Pseudomonas aeruginosa growth and reduces biofilm biomass and pyocyanin production

Frontiers in Cellular and Infection Microbiology
BackgroundPseudomonas aeruginosa remains a serious threat in clinical settings, especially among patients who are immunocompromised, receiving chemotherapy, or in intensive care units.
Needa A. Bahkali, Rhodanne Nicole A. Lambarte, Terrence S. Sumague, Turki M. Dawoud, Khalid S. Almaary, Abdurahman A. Niazy, Abdurahman A. Niazy   +6 more
doaj   +1 more source

Prospective Study of Targeted Busulfan–Fludarabine Conditioning for Hematopoietic Stem Cell Transplantation in Genetic Rare Diseases

European Journal of Haematology, EarlyView.
ABSTRACT Objectives Genetic rare diseases (GRDs), including chronic granulomatous disease, familial hemophagocytic lymphohistiocytosis, and congenital neutropenia, often require hematopoietic stem cell transplantation (HSCT) as the only curative option.
Bo Kyung Kim, Kyung Taek Hong, Jung Yoon Choi, Hyun Jin Park, Kyung‐Sang Yu, In‐Jin Jang, Hyoung Jin Kang   +6 more
wiley   +1 more source

Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study

Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier, Nathalie Cozic, Marie‐Dominique Tabone, Gaelle Pierron, Perrine Marec‐Berard, Sarah Winter, Gabriel Revon‐Rivière, Cyril Lervat, Dominique Plantaz, Marie‐Pierre Castex, Gregory Guimard, Estelle Thebaud, Stephanie Proust, Laure Saumet, Natacha Entz‐Werle, Sophie Taque, Cécile Vérité, Marta Jimenez, Nathalie Gaspar   +18 more
wiley   +1 more source

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

Review of the pharmacokinetics and pharmacodynamics of intravenous busulfan in paediatric patients

, 2020
We aimed to review the pharmacokinetics (PK) of intravenous busulfan in paediatric patients, identify covariate factors influencing exposure, investigate evidence of changes in PK behaviour over time, and correlate exposure with efficacy and toxicity ...
Staatz, Christine E., Fraser, Christopher J., Lawson, Rachael, Hennig, Stefanie   +3 more
core   +1 more source

Antioxidant effects of alpha-tocopherol (vitamine E) on testis regeneration in busulfan-treated mice

Iranian South Medical Journal, 2016
Background: Busulfan is a chemotherapy medicine for treatment of cancer. This medicine has cytotoxic effects on different organs of animal. Since the use of chemotherapy medicine are increasing due to individuals get involved to cancer, thus preserving ...
Fatemeh Rohnavaz, Toba Mirzapour, Abolfazl Bayrami, Marya Zahiri   +3 more
doaj  

Successful Management of Severe Hepatic Acute Graft‐Versus‐Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation in a Child With β‐Thalassemia Major: Clinical Lessons From Early Therapeutic Escalation

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Severe hepatic acute graft‐versus‐host disease can occur early after allogeneic hematopoietic stem cell transplantation without skin involvement, presenting with rapidly progressive cholestatic liver dysfunction. Early recognition and prompt escalation to multimodal immunosuppressive therapy achieve complete biochemical remission and durable ...
Hind Alhiraki, Amal Ali Fares, Maged Kheder   +2 more
wiley   +1 more source