Results 191 to 200 of about 30,342 (234)

Effects of butylated hydroxytoluene on Tetrahymena pyriformis

Food and Cosmetics Toxicology, 1976
The biological effect of butylated hydroxyanisole (BHA) at the molecular level in a eukaryotic system was studied using Tetrahymena pyriformis. BHA at 20 ppm in the medium inhibited cell growth by 50% and the synthesis of DNA, RNA and protein also by 50%. Kinetic experiments indicated that inhibition of the synthesis of all three types of macromolecule
J G, Surak, R L, Bradley, A L, Branen, W E, Ribelin, E, Shrago   +4 more
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Haemorrhagic Toxicosis in Rats Given Butylated Hydroxytoluene

Acta Pharmacologica et Toxicologica, 1981
Abstract: Vascular permeability, platelet function, blood coagulation and fibrinolytic activity were examined in Sprague‐Dawley male rats given 1.20% butylated hydroxytoluene (BHT) in the diet for 1 week. BHT significantly increased the leakage of Evans blue from blood into epididymus.
O, Takahashi, K, Hiraga
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Comparative pharmacokinetics of butylated hydroxyanisole and butylated hydroxytoluene in rabbits

Journal of Pharmaceutical Sciences, 1980
The widespread use of butylated hydroxyanisole (I) and butylated hydroxytoluene (II) as food antioxidants recently has been criticized by the Food and Drug Administration because of their pharmacological and toxicological effects. Interest also has arisen recently in the use of these compounds as anticancer agents.
R, El-Rashidy, S, Niazi
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Butylated hydroxytoluene as a skin lightener.

Archives of dermatology, 1974
The possible skin lightening properties of butylated hydroxytoluene were investigated by patch testing and a normal usage test on black-skinned volunteers. No evidence of depigmentation was observed in this series.
B, Bentley-Phillips, M A, Bayles
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Butylated Hydroxytoluene Toxicity

1992
The phenolic antioxidant butylated hydroxytoluene (BHT) causes toxic effects in experimental animals including hemorrhage, lung, liver and kidney injury, and tumor promotion. ADI values of 0–0.125 (WHO) and 0–0.05 (EEC) mg/kg body weight have been derived from toxicological animal studies.
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Excretion of dietary butylated hydroxytoluene by the rat

Toxicology Letters, 1980
The concentration of phenols in the urine or feces of rats receiving a diet containing 1.00% butylated hydroxytoluene (BHT) for 10 days was determined colorimetrically. The cumulative intake of BHT was approx. 5.0 mmol/rat for 10 days. The total amount of phenols excreted in urine and feces was 3.65 mmol/rat for 10 days, i.e.
O, Takahashi, K, Hiraga
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Antioxidant synergism between butylated hydroxyanisole and butylated hydroxytoluene

Journal of the American Oil Chemists' Society, 1995
AbstractDecay of the 2,6‐di‐tert‐butyl‐4‐methylphenoxy radical [butylated hydroxytoluene (BHT)‐radical] in the presence of butylated hydroxyanisole (BHA) was investigated in 1,2‐dimethoxyethane with or without triethylamine. BHT‐radical was conveniently generated by dissociation of its unstable dimer in solution.
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Potentiation of vitamin A hepatotoxicity by butylated hydroxytoluene

Toxicology and Applied Pharmacology, 1987
The interaction between the natural vitamin A ester retinyl acetate (RA) and the phenolic antioxidant butylated hydroxytoluene (BHT) in the induction of biliary hyperplasia and hepatic fibrosis in female Sprague-Dawley rats was characterized. Using a 3 X 3 matrix design, rats were fed diets supplemented with (per kilogram diet) 0, 125, or 250 mg RA and/
D L, McCormick, T A, Hultin, C J, Detrisac   +2 more
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Metabolism and pulmonary toxicity of butylated hydroxytoluene (BHT)

Pharmacology & Therapeutics, 1989
Revue de synthese sur le butylhydroxytoluene: metabolisme, toxicite pulmonaire, utilisation en tant qu'outil ...
H, Witschi, A M, Malkinson, J A, Thompson   +2 more
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Butylated hydroxytoluene, lipid-enveloped viruses, and AIDS

Medical Hypotheses, 1987
Butylated hydroxytoluene (BHT) is a potent inactivator of lipid-enveloped viruses. The viral envelope structure is physically disturbed by BHT, thereby interfering with viral adsorption to host cells. Since the virus responsible for AIDS (HTLV III) contains a lipid envelope, BHT warrants investigation as a potential antiviral agent against the AIDS ...
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