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A reverse transcription-quantitative polymerase chain reaction system for evaluating intestinal butyrate production by fecal bacteria [PDF]
Applied and Environmental MicrobiologyIntestinal butyrate is key in maintaining host health. As an indicator of butyrate production, the fecal butyrate concentration is used for assessing health status; however, it may not be a suitable marker as it only accounts for residual fecal butyrate ...
Mai Hane +7 more
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Sodium oligomannate modulates the gut-brain axis to alleviate post-stroke cognitive impairment by restoring butyrate metabolism [PDF]
MicrobiomeBackground Post-stroke cognitive impairment (PSCI) affects up to half of stroke survivors, severely impacting their quality of life. Despite its prevalence, the pathogenesis of PSCI remains poorly understood, and no specific pharmacological treatments ...
Yueran Ren +10 more
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Cells, 2021 The microbial metabolite butyrate serves as a link between the intestinal microbiome and epithelium. The monocarboxylate transporters MCT1 and SMCT1 are the predominant means of butyrate transport from the intestinal lumen to epithelial cytoplasm, where ...
Pooja S. Salvi, Robert A. Cowles
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Butyrate Properties in Immune-Related Diseases: Friend or Foe?
Fermentation, 2023 Butyrate is a short-chain fatty acid (SCFA) created within the intestinal lumen by bacterial fermentation of largely undigested dietary carbohydrates.
Muhammad Anshory +7 more
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Encapsulation of butyrate using low-alkali konjac gel induced by ethanol for colonic delivery
Food Hydrocolloids for Health, 2021 Butyrate administrated in proper concentration is beneficial to the human colon environment. However, the delivery of butyrate to the colon is quite difficult as butyrate could be easily absorbed in the upper gastrointestinal tract.
Yousong Ma +3 more
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Redox Biology, 2023 Ferroptosis has emerged to be a promising approach in cancer therapies; however, colorectal cancer (CRC) is relatively insensitive to ferroptosis. Exactly how the gut microenvironment impacts the ferroptotic sensitivity of CRC remains unknown. Herein, by
Ying He +15 more
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Polyvinyl Butyrate Nanoparticles as Butyrate Donors for Colitis Treatment
ACS Applied Bio Materials, 2021 Butyrate has been attracting attention for the suppression of inflammatory bowel disease (IBD). However, clinical trials of butyrate for IBD treatment have resulted in controversial outcomes, likely owing to the adverse effect of butyrate on the intestinal epithelium that was observed at high butyrate concentrations.
Yunmei Mu +9 more
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Nauchno-prakticheskii zhurnal «Patogenez», 2021 Бутановая кислота - одна из короткоцепочечных жирных кислот (КЖК). Присутствует в молочных продуктах и сливочном масле, поэтому имеет второе название - масляная (бутират). Как и другие КЖК, образуется в толстом кишечнике человека местной анаэробной флорой из грубой растительной пищи - пищевых волокон.
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Veterinary Research, 2020 Butyrate has been used extensively as a feed additive to improve gut health and to decrease Salmonella colonization in poultry. Salmonella mainly colonizes the ceca so butyrate concentrations should be increased in this gut segment.
Lonneke Onrust +4 more
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Frontiers in Microbiology, 2021 One of the primary benefits associated with dietary resistant starch (RS) is the production of butyrate by the gut microbiome during fermentation of this fiber in the large intestine. The ability to degrade RS is a relatively rare trait among microbes in
June Teichmann, Darrell W. Cockburn
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