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A reverse transcription-quantitative polymerase chain reaction system for evaluating intestinal butyrate production by fecal bacteria. [PDF]

open access: yesAppl Environ Microbiol
Intestinal butyrate is key in maintaining host health. As an indicator of butyrate production, the fecal butyrate concentration is used for assessing health status; however, it may not be a suitable marker as it only accounts for residual fecal butyrate ...
Hane M   +7 more
europepmc   +2 more sources

Butyrate and the Intestinal Epithelium: Modulation of Proliferation and Inflammation in Homeostasis and Disease

open access: yesCells, 2021
The microbial metabolite butyrate serves as a link between the intestinal microbiome and epithelium. The monocarboxylate transporters MCT1 and SMCT1 are the predominant means of butyrate transport from the intestinal lumen to epithelial cytoplasm, where ...
Pooja S. Salvi, Robert A. Cowles
doaj   +1 more source

Butyrate Properties in Immune-Related Diseases: Friend or Foe?

open access: yesFermentation, 2023
Butyrate is a short-chain fatty acid (SCFA) created within the intestinal lumen by bacterial fermentation of largely undigested dietary carbohydrates.
Muhammad Anshory   +7 more
doaj   +1 more source

Polyvinyl Butyrate Nanoparticles as Butyrate Donors for Colitis Treatment

open access: yesACS Applied Bio Materials, 2021
Butyrate has been attracting attention for the suppression of inflammatory bowel disease (IBD). However, clinical trials of butyrate for IBD treatment have resulted in controversial outcomes, likely owing to the adverse effect of butyrate on the intestinal epithelium that was observed at high butyrate concentrations.
Yunmei Mu   +9 more
openaire   +3 more sources

Encapsulation of butyrate using low-alkali konjac gel induced by ethanol for colonic delivery

open access: yesFood Hydrocolloids for Health, 2021
Butyrate administrated in proper concentration is beneficial to the human colon environment. However, the delivery of butyrate to the colon is quite difficult as butyrate could be easily absorbed in the upper gastrointestinal tract.
Yousong Ma   +3 more
doaj   +1 more source

Butyrate reverses ferroptosis resistance in colorectal cancer by inducing c-Fos-dependent xCT suppression

open access: yesRedox Biology, 2023
Ferroptosis has emerged to be a promising approach in cancer therapies; however, colorectal cancer (CRC) is relatively insensitive to ferroptosis. Exactly how the gut microenvironment impacts the ferroptotic sensitivity of CRC remains unknown. Herein, by
Ying He   +15 more
doaj   +1 more source

In vitro Fermentation Reveals Changes in Butyrate Production Dependent on Resistant Starch Source and Microbiome Composition

open access: yesFrontiers in Microbiology, 2021
One of the primary benefits associated with dietary resistant starch (RS) is the production of butyrate by the gut microbiome during fermentation of this fiber in the large intestine. The ability to degrade RS is a relatively rare trait among microbes in
June Teichmann, Darrell W. Cockburn
doaj   +1 more source

Butyric acid (butyrate)

open access: yesNauchno-prakticheskii zhurnal «Patogenez», 2021
Бутановая кислота - одна из короткоцепочечных жирных кислот (КЖК). Присутствует в молочных продуктах и сливочном масле, поэтому имеет второе название - масляная (бутират). Как и другие КЖК, образуется в толстом кишечнике человека местной анаэробной флорой из грубой растительной пищи - пищевых волокон.
openaire   +2 more sources

Decrease in acetyl-CoA pathway utilizing butyrate-producing bacteria is a key pathogenic feature of alcohol-induced functional gut microbial dysbiosis and development of liver disease in mice

open access: yesGut Microbes, 2021
Emerging research evidence has established the critical role of the gut-liver axis in the development of alcohol-associated liver disease (ALD). The present study employed 16S rRNA gene and whole genome shotgun (WGS) metagenomic analysis in combination ...
Richa Singhal   +15 more
doaj   +1 more source

Butyrate producers, “The Sentinel of Gut”: Their intestinal significance with and beyond butyrate, and prospective use as microbial therapeutics

open access: yesFrontiers in Microbiology, 2023
Gut-microbial butyrate is a short-chain fatty acid (SCFA) of significant physiological importance than the other major SCFAs (acetate and propionate).
Vineet Singh   +7 more
doaj   +1 more source

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