Carbon dioxide and fruit odor transduction in Drosophila olfactory neurons. What controls their dynamic properties? [PDF]
, 2014 We measured frequency response functions between odorants and action potentials in two types of neurons in Drosophila antennal basiconic sensilla. CO2 was used to stimulate ab1C neurons, and the fruit odor ethyl butyrate was used to stimulate ab3A ...
French, Andrew S +3 more
core +9 more sources
Veterinary Research, 2020 Butyrate has been used extensively as a feed additive to improve gut health and to decrease Salmonella colonization in poultry. Salmonella mainly colonizes the ceca so butyrate concentrations should be increased in this gut segment.
Lonneke Onrust +4 more
doaj +1 more source
Gut Microbiome, 2022 Metabolites produced by microbial fermentation in the human intestine, especially short-chain fatty acids (SCFAs), are known to play important roles in colonic and systemic health.
Maria LaBouyer +11 more
doaj +1 more source
Alternative splicing regulated by butyrate in bovine epithelial cells. [PDF]
PLoS ONE, 2012 As a signaling molecule and an inhibitor of histone deacetylases (HDACs), butyrate exerts its impact on a broad range of biological processes, such as apoptosis and cell proliferation, in addition to its critical role in energy metabolism in ruminants ...
Sitao Wu +4 more
doaj +1 more source
Experiments and simulations on short chain fatty acid production in a colonic bacterial community [PDF]
, 2018 Understanding how production of specific metabolites by gut microbes is modulated by interactions with surrounding species and by environmental nutrient availability is an important open challenge in microbiome research.
Bobrow, Johanna +6 more
core +1 more source
Butyrate induces ROS-mediated apoptosis by modulating miR-22/SIRT-1 pathway in hepatic cancer cells
Redox Biology, 2017 Butyrate is one of the short chain fatty acids, produced by the gut microbiota during anaerobic fermentation of dietary fibres. It has been shown that it can inhibit tumor progression via suppressing histone deacetylase and can induce apoptosis in cancer
Kishor Pant +5 more
doaj +1 more source
Histone deacetylase inhibitors induce invasion of human melanoma cells in vitro via differential regulation of N-cadherin expression and RhoA activity [PDF]
, 2016 Background: Histone deacetylase inhibitors (HDACi) exert multiple cytotoxic actions on cancer cells. Currently, different synthetic HDACi are in clinical use or clinical trials; nevertheless, since both pro-invasive and anti-invasive activities have been
Andrade, Ricardo +6 more
core +4 more sources
Plasma metabolites reflect seasonally changing metabolic processes in a long-distance migrant shorebird (Calidris canutus) [PDF]
, 2002 Migrant birds have tightly scheduled annual cycles consisting of several distinct life cycle (sub-)stages such as reproduction, migration, moult and overwintering, each of which have specific metabolic requirements (e.g., fattening during migration ...
Jenni, Lukas, +2 more
core +2 more sources
Journal of Pharmacological Sciences, 2021 Short chain fatty acids readily crosses the gut-blood and blood–brain barrier and acts centrally to influence neuronal signaling. We hypothesized that butyrate, a short-chain fatty acid produced by bacterial fermentation, in the central nervous system ...
Toshikatsu Okumura +5 more
doaj +1 more source
Mast cell clones: a model for the analysis of cellular maturation. [PDF]
, 1982 Cloned mouse mast cells resemble, by ultrastructure, immature mast cells observed in vivo. These mast cell clones can be grown in the absence of any other cells, facilitating direct investigations of their biochemistry and function.
Cantor, H +10 more
core +2 more sources