Results 31 to 40 of about 120,336 (337)

Sodium Butyrate Ameliorates Oxidative Stress-Induced Intestinal Epithelium Barrier Injury and Mitochondrial Damage through AMPK-Mitophagy Pathway

Oxidative Medicine and Cellular Longevity, 2022
Sodium butyrate has gained increasing attention for its vast beneficial effects. However, whether sodium butyrate could alleviate oxidative stress‐induced intestinal dysfunction and mitochondrial damage of piglets and its underlying mechanism remains ...
Xin Li, Chunchun Wang, Jiang Zhu, Qian Lin, Minjie Yu, J.S. Wen, Jie Feng, Caihong Hu   +7 more
semanticscholar   +1 more source

Butyrate to combat obesity and obesity‐associated metabolic disorders: Current status and future implications for therapeutic use

Obesity Reviews, 2022
Evidence is increasing that disturbances in the gut microbiome may play a significant role in the etiology of obesity and type 2 diabetes. The short chain fatty acid butyrate, a major end product of the bacterial fermentation of indigestible ...
Thirza van Deuren, E. Blaak, E. E. Canfora   +2 more
semanticscholar   +1 more source

Treatment of peanut allergy and colitis in mice via the intestinal release of butyrate from polymeric micelles

Nature Biomedical Engineering, 2022
Intragastrically delivered polymeric micelles releasing butyrate along the intestinal tract restore barrier-protective responses in mouse models of peanut allergy and colitis.
Ruyi Wang, Shijie Cao, M. H. Bashir, Lauren A. Hesser, Yanlin Su, Sung Min Choi Hong, Andrew Thompson, Elliot Culleen, Matthew Sabados, N. Dylla, Evelyn Campbell, R. Bao, Eric B. Nonnecke, C. Bevins, D. Wilson, J. Hubbell, C. Nagler   +16 more
semanticscholar   +1 more source

The Protective Role of Butyrate against Obesity and Obesity-Related Diseases

Molecules, 2021
Worldwide obesity is a public health concern that has reached pandemic levels. Obesity is the major predisposing factor to comorbidities, including type 2 diabetes, cardiovascular diseases, dyslipidemia, and non-alcoholic fatty liver disease.
S. Coppola, C. Avagliano, A. Calignano, R. Berni Canani   +3 more
semanticscholar   +1 more source

Formation of propionate and butyrate by the human colonic microbiota.

Environmental Microbiology, 2017
The human gut microbiota ferments dietary non-digestible carbohydrates into short-chain fatty acids (SCFA). These microbial products are utilized by the host and propionate and butyrate in particular exert a range of health-promoting functions.
P. Louis, H. Flint
semanticscholar   +1 more source

The Future of Butyric Acid in Industry [PDF]

The Scientific World Journal, 2012
In this paper, the different applications of butyric acid and its current and future production status are highlighted, with a particular emphasis on the biofuels industry. As such, this paper discusses different issues regarding butyric acid fermentations and provides suggestions for future improvements and their approaches.
Dwidar, Mohammed, Park, Jae-Yeon, Mitchell, Robert J., Sang, Byoung-In   +3 more
openaire   +5 more sources

Protective role of butyrate in obesity and diabetes: New insights

Frontiers in Nutrition, 2022
Studies in human microbiota dysbiosis have shown that short-chain fatty acids (SCFAs) like propionate, acetate, and particularly butyrate, positively affect energy homeostasis, behavior, and inflammation.
Arianna Mayorga-Ramos, Carlos Barba-Ostria, D. Simancas-Racines, Linda P. Guamán   +3 more
semanticscholar   +1 more source

Therapeutic Effects of Butyrate on Pediatric Obesity

JAMA Network Open, 2022
Key Points Question Can oral butyrate supplementation as adjunct to standard care be effective in the treatment of pediatric obesity? Findings In this randomized clinical trial including 54 children with obesity, a 40% absolute increase in the rate of ...
S. Coppola, R. Nocerino, L. Paparo, G. Bedogni, A. Calignano, C. di Scala, Anna Fiorenza de Giovanni di Santa Severina, F. De Filippis, D. Ercolini, R. Berni Canani   +9 more
semanticscholar   +1 more source

Butyrate Supplementation at High Concentrations Alters Enteric Bacterial Communities and Reduces Intestinal Inflammation in Mice Infected with Citrobacter rodentium

mSphere, 2017
Butyrate is a short-chain fatty acid by-product of the microbial fermentation of dietary fermentable materials in the large intestine; it is the main energy source for enterocyte regeneration, modulates the enteric microbial community, and contributes to
Janelle A. Jiminez, Trina C. Uwiera, D. Wade Abbott, Richard R. E. Uwiera, G. Douglas Inglis   +4 more
doaj   +1 more source

Gut bacteria identified in colorectal cancer patients promote tumourigenesis via butyrate secretion

Nature Communications, 2021
Emerging evidence is revealing that alterations in gut microbiota are associated with colorectal cancer (CRC). However, very little is currently known about whether and how gut microbiota alterations are causally associated with CRC development.
S. Okumura, Y. Konishi, Megumi Narukawa, Y. Sugiura, S. Yoshimoto, Yuriko Arai, Shintaro Sato, Y. Yoshida, Shunya Tsuji, Ken Uemura, Masahiro Wakita, T. Matsudaira, Tomonori Matsumoto, Shimpei Kawamoto, Akiko Takahashi, Yoshiro Itatani, H. Miki, M. Takamatsu, K. Obama, K. Takeuchi, M. Suematsu, Naoko Ohtani, Y. Fukunaga, M. Ueno, Y. Sakai, S. Nagayama, E. Hara   +26 more
semanticscholar   +1 more source