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Butyration of Lignosulfonate with Butyric Anhydride in the Presence of Choline Chloride
A novel process was developed for the butyration of lignosulfonate (LS) with butyric anhydride in the presence of choline chloride at elevated temperatures. The degree of substitution (DS) was qualitatively and quantitatively determined by Fourier transform infrared spectroscopy using the baseline method.
Fangchao Cheng, Yingcheng Hu, Lifen Li
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New insight into butyrate metabolism [PDF]
Butyrate is a C4acid produced by microbial fermentation of carbohydrates and protein in the large intestine of all animal species. The factor of prime importance for the production rate of butyrate in the lower gut is type and levels of non-digestible carbohydrates entering the large intestine.
Bach Knudsen, Knud Erik+3 more
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Defects in the mucosal barrier have been associated with metabolic diseases such as obesity and non-alcoholic fatty liver disease (NAFLD). Mice fed a Western-style diet (WSD) develop obesity and are characterized by a diet-induced intestinal barrier ...
J. Beisner+5 more
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Transcriptome characterization by RNA-seq unravels the mechanisms of butyrate-induced epigenomic regulation in bovine cells. [PDF]
Short-chain fatty acids (SCFAs), especially butyrate, affect cell differentiation, proliferation, and motility. Butyrate also induces cell cycle arrest and apoptosis through its inhibition of histone deacetylases (HDACs).
Sitao Wu+3 more
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Design of synthetic human gut microbiome assembly and butyrate production
The capability to design microbiomes with predictable functions would enable new technologies for applications in health, agriculture, and bioprocessing.
Ryan L. Clark+6 more
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Butyrate-induced transcriptional changes in human colonic mucosa. [PDF]
Fermentation of dietary fiber in the colon results in the production of short chain fatty acids (mainly propionate, butyrate and acetate). Butyrate modulates a wide range of processes, but its mechanism of action is mostly unknown.
Steven A L W Vanhoutvin+8 more
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Muscle protein catabolism in patients with diabetic nephropathy (DN) results in striking loss of muscle proteins, which increases morbidity and mortality risks.
Gang Tang+7 more
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Liquid chromatographic estimation of (S) - glycidyl butyrate in (R) - glycidyl butyrate
The present study was undertaken out of a commercial need for the synthesis of Linezolid with impurity limits within the specification.(R)-Glycidyl butyrate (RGB) is raw material for the synthesis of Linezolid drug substance. This RGB contains (S)-(+)-Glycidyl butyrate (SGB) and SGB appears in same concentration in the final Active Pharmaceutical ...
Sukumar Sinha+3 more
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Short-chain fatty acids, especially butyrate, play beneficial roles in sustaining gastrointestinal health. However, due to limitations associated with direct consumption of butyrate, there has been interest in using prodrugs of butyrate. Tributyrin (TB),
Dah Hyun Jung+4 more
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Colonic butyrate- algesic or analgesic? [PDF]
Irritable bowel syndrome (IBS) is a common health issue that is characterized by abdominal pain, abnormal bowel movements, and altered visceral perception. The complexity and variability in symptoms pose serious challenges in treating IBS. Current therapy for IBS is primarily focused on reducing the abdominal pain, thereby improving the quality of life
Pradeep Kannampalli+2 more
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