Results 41 to 50 of about 174,283 (288)

Polysaccharide utilization loci and nutritional specialization in a dominant group of butyrate-producing human colonic Firmicutes [PDF]

, 2015
Acknowledgements The Rowett Institute of Nutrition and Health (University of Aberdeen) receives financial support from the Scottish Government Rural and Environmental Sciences and Analytical Services (RESAS).
Bernalier-Donadille, Annick, Browne, Hilary P., Duncan, Sylvia H., Flint, Harry J., Harris, Hugh M. B., Lawley, Trevor D., Martin, Jennifer C., O'Toole, Paul W., Scott, Karen P., Sheridan, Paul O.   +9 more
core   +3 more sources

Butyrate inhibits histone deacetylase 2 expression to alleviate liver fibrosis in biliary atresia

BMC Pediatrics
Background Previous studies have found a reduction in butyrate-producing bacteria in the gut microbiota of infants with biliary atresia (BA). Butyrate is also an important inhibitor of histone deacetylase 2 (HDAC2).
Yilin Zhao, Xiaodan Xu, Shaowen Liu, Xueting Wang, Jiayinaxi Musha, Tengfei Li, Liang Ge, Yan Sun, Shujian Zhang, Li Zhao, Jianghua Zhan   +10 more
doaj   +1 more source

Iron Modulates Butyrate Production by a Child Gut Microbiota In Vitro

mBio, 2015
The aim of this study was to investigate the effect of iron (Fe) availability on butyrate production in the complex bacterial ecosystem of the human gut.
Alexandra Dostal, Christophe Lacroix, Lea Bircher, Van Thanh Pham, Rainer Follador, Michael Bruce Zimmermann, Christophe Chassard   +6 more
doaj   +1 more source

Proteomics unveil a central role for peroxisomes in butyrate assimilation of the heterotrophic Chlorophyte alga Polytomella sp.

Frontiers in Microbiology, 2022
Volatile fatty acids found in effluents of the dark fermentation of biowastes can be used for mixotrophic growth of microalgae, improving productivity and reducing the cost of the feedstock.
Julien Lacroux, Ariane Atteia, Sabine Brugière, Yohann Couté, Olivier Vallon, Jean-Philippe Steyer, Robert van Lis   +6 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Role of gut microbiota in the aetiology of obesity: proposed mechanisms and review of the literature [PDF]

, 2016
The aetiology of obesity has been attributed to several factors (environmental, dietary, lifestyle, host, and genetic factors); however none of these fully explain the increase in the prevalence of obesity worldwide.
Edwards, Christine Ann, Gerasimidis, Konstantinos, Khan, Muhammad Jaffar, Shaikh, M. Guftar   +3 more
core   +3 more sources

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Sodium Butyrate Ameliorates Gut Microbiota Dysbiosis in Lupus-Like Mice

Frontiers in Nutrition, 2020
Gut microbiota has a strong influence on the onset and development of systemic lupus erythematosus (SLE), and several studies have demonstrated the effectiveness of microbiota-derived butyrate to ameliorate SLE.
Hanchang He, Hanchang He, Haoming Xu, Jing Xu, Hailan Zhao, Qianyun Lin, Youlian Zhou, Yuqiang Nie   +7 more
doaj   +1 more source

Temperature‐Robust Interphase Enables Carboxylate‐Ester Electrolyte for Stabilizing High‐Voltage Sodium Batteries

Advanced Functional Materials, EarlyView.
A synergistic electrolyte engineering strategy of employing ethyl acetate (EA) with vinylene carbonate (VC) as multifunctional additives is initially pioneered, making various as‐prepared high‐voltage wide‐temperature sodium batteries work well via the formation of a gradient and temperature‐robust interphase.
Huihua Li, Shuaijie Chang, Hongxu Qu, Jian Wang, Fanglin Wu, Minghua Chen, Huang Zhang   +6 more
wiley   +1 more source

Sodium oligomannate modulates the gut-brain axis to alleviate post-stroke cognitive impairment by restoring butyrate metabolism

Microbiome
Background Post-stroke cognitive impairment (PSCI) affects up to half of stroke survivors, severely impacting their quality of life. Despite its prevalence, the pathogenesis of PSCI remains poorly understood, and no specific pharmacological treatments ...
Yueran Ren, Jingru Liang, Jiahui Xie, Weike Hu, Minlin Lai, Xiao Li, Jiafeng Zhang, Yifeng Zheng, Qiheng Wu, Hongwei Zhou, Jia Yin   +10 more
doaj   +1 more source