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With the increasing amount of evidence linking certain disorders of the human body to a disturbed gut microbiota, there is a growing interest for compounds that positively influence its composition and activity through diet.
A. Rivière+4 more
semanticscholar +1 more source
Butyric Acid Is Synthesized by Piglets [PDF]
We hypothesized that there is no synthesis of butyric acid within organs or tissues not drained by the portal vein (PV). Two experiments were performed. In six piglets, the colonic vasculature was clamped (n = 4) or the entire colon resected while [1-13C]-butyric acid (99% enriched) was infused into a jejunal vein for 120 min; 13C enrichment of butyric
C L Kien, J C Chang, J R Cooper
openaire +2 more sources
Butyrate: A Double-Edged Sword for Health?
Butyrate, a four-carbon short-chain fatty acid, is produced through microbial fermentation of dietary fibers in the lower intestinal tract. Endogenous butyrate production, delivery, and absorption by colonocytes have been well documented. Butyrate exerts
Hu Liu+6 more
semanticscholar +1 more source
Make (No) Bones about Butyrate [PDF]
In this issue of Immunity, Tyagi et al. (2018) report that the microbial metabolite butyrate orchestrates the interplay between regulatory T cells and CD8+ T cells, increasing Wnt signaling, and promoting bone formation in young mice.
Benjamin J. Marsland, Christina Begka
openaire +3 more sources
Encapsulation of butyrate using low-alkali konjac gel induced by ethanol for colonic delivery
Butyrate administrated in proper concentration is beneficial to the human colon environment. However, the delivery of butyrate to the colon is quite difficult as butyrate could be easily absorbed in the upper gastrointestinal tract.
Yousong Ma+3 more
doaj
Digestion of dietary fibers by gut bacteria has been shown to stimulate intestinal mineral absorption [e.g., calcium (Ca2+) and magnesium (Mg2+)]. Although it has been suggested that local pH and short-chain fatty acid (SCFA) concentrations determine ...
Lisanne M. M. Gommers+8 more
doaj +1 more source
Short chain fatty acid (SCFA) butyrate has various beneficial effects on the gut microbiota as well as on the overall health status and metabolism of the host organism.
Gábor Mátis+8 more
doaj +1 more source
Butyrate and the Fine-Tuning of Colonic Homeostasis: Implication for Inflammatory Bowel Diseases
This review describes current evidence supporting butyrate impact in the homeostatic regulation of the digestive ecosystem in health and inflammatory bowel diseases (IBDs). Butyrate is mainly produced by bacteria from the Firmicutes phylum. It stimulates
N. Gasaly, M. Hermoso, M. Gotteland
semanticscholar +1 more source
Ferroptosis has emerged to be a promising approach in cancer therapies; however, colorectal cancer (CRC) is relatively insensitive to ferroptosis. Exactly how the gut microenvironment impacts the ferroptotic sensitivity of CRC remains unknown. Herein, by
Ying He+15 more
doaj
Volatile fatty acids found in effluents of the dark fermentation of biowastes can be used for mixotrophic growth of microalgae, improving productivity and reducing the cost of the feedstock.
Julien Lacroux+6 more
doaj +1 more source