Results 61 to 70 of about 120,336 (337)

Butyrate enhances CPT1A activity to promote fatty acid oxidation and iTreg differentiation

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2021
Significance Inducible Treg (iTreg) cells are crucial for the maintenance of intestinal immune homeostasis. iTreg differentiation has been recently linked with metabolic reprogramming in fatty acid oxidation (FAO).
Fengqi Hao   +11 more
semanticscholar   +1 more source

Sodium Butyrate Ameliorates Gut Microbiota Dysbiosis in Lupus-Like Mice

open access: yesFrontiers in Nutrition, 2020
Gut microbiota has a strong influence on the onset and development of systemic lupus erythematosus (SLE), and several studies have demonstrated the effectiveness of microbiota-derived butyrate to ameliorate SLE.
Hanchang He   +7 more
doaj   +1 more source

Prospects for clinical applications of butyrate-producing bacteria

open access: yesWorld Journal of Clinical Pediatrics, 2021
As the major source of energy for colonic mucosal cells and as an important regulator of gene expression, inflammation, differentiation, and apoptosis in host cells, microbiota-derived butyrate can enhance the intestinal mucosal immune barrier, modulate ...
Libin Zhu   +3 more
semanticscholar   +1 more source

The Glycogenic Properties of Butyric Acid [PDF]

open access: yesActa Veterinaria Scandinavica, 1968
When butyric acid was injected intravenously at an amount of 2.5 mM/kg, blood glucose rose markedly in normal sheep. In a ewe with pregnancy toxemia blood glucose did not change. When the same amount was injected intraruminally to sheep and cows, the plasma level of non-esterified fatty acids, NEFA, was in most cases decreased by about 30—50 %, while ...
G. Jonson, J. Luthman
openaire   +3 more sources

Butyrate inhibits histone deacetylase 2 expression to alleviate liver fibrosis in biliary atresia

open access: yesBMC Pediatrics
Background Previous studies have found a reduction in butyrate-producing bacteria in the gut microbiota of infants with biliary atresia (BA). Butyrate is also an important inhibitor of histone deacetylase 2 (HDAC2).
Yilin Zhao   +10 more
doaj   +1 more source

Iron Modulates Butyrate Production by a Child Gut Microbiota In Vitro

open access: yesmBio, 2015
The aim of this study was to investigate the effect of iron (Fe) availability on butyrate production in the complex bacterial ecosystem of the human gut.
Alexandra Dostal   +6 more
doaj   +1 more source

Stigmasterol Restores the Balance of Treg/Th17 Cells by Activating the Butyrate-PPARγ Axis in Colitis

open access: yesFrontiers in Immunology, 2021
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder with gut microbiota disequilibrium and regulatory T (Treg)/T helper 17 (Th17) immune imbalance. Stigmasterol, a plant-derived sterol, has shown anti-inflammatory effects. Our study aimed
Shuting Wen   +6 more
semanticscholar   +1 more source

Natural Design of a Stabilized Cross‐β Fold: Structure of the FuA FapC from Pseudomonas Sp. UK4 Reveals a Critical Role for Stacking of Imperfect Repeats

open access: yesAdvanced Materials, EarlyView.
We report a 3.2 Å cryoEM structure of functional amyloid protein FapC from Pseudomonas sp. UK4, an essential component of bacterial biofilm, which reveals a Greek key‐shaped protofilament, supports bioinformatically determined motifs, nuances AlphaFold predictions, emphasizes heterogeneous cross‐β stacking in amyloid cross‐seeding and shows strain ...
Yanting Jiang   +13 more
wiley   +1 more source

Suppression of fibrosis in human pterygium fibroblasts by butyrate and phenylbutyrate [PDF]

open access: yesInternational Journal of Ophthalmology, 2017
AIM: To evaluate the antifibrogenic effects of butyrate or phenylbutyrate, a chemical derivative of butyrate, in human pterygium fibroblasts. METHODS: Human pterygium fibroblasts obtained from patient pterygium tissue were treated with butyrate or ...
Yuka Koga   +7 more
doaj   +1 more source

Expanding the Particle Range for Biocatalytically Active Pickering Emulsions with Silicone Coatings

open access: yesAdvanced Materials, EarlyView.
Pickering emulsions are a promising class of reaction systems for biocatalysis. However, only a few materials can stabilize the required w/o emulsion. In this study, it is demonstrated that coating microparticles with modified silicone is a straightforward, versatile, and tunable method for producing appropriate particles. Consequently, enzyme carriers
Sara Fatima Bhutta   +2 more
wiley   +1 more source

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