Results 71 to 80 of about 183,656 (338)

Butyrate administration is not sufficient to improve immune reconstitution in antiretroviral-treated SIV-infected macaques [PDF]

open access: gold, 2022
Alexandra M. Ortiz   +10 more
openalex   +1 more source

Development of Endogenous Protein Probes for Characterizing Surface Proteins and Cellular Interactors of Extracellular Vesicles

open access: yesAdvanced Science, EarlyView.
The proximity labeling enzyme APEX2 is displayed on extracellular vesicle (EV) surfaces via genetic fusion with EV‐sorting scaffolds, enabling in situ biotinylation of native surface proteins, adsorbed corona components, and interacting cellular proteins.
Wenyi Zheng   +5 more
wiley   +1 more source

Butyrate production in the acetogen Eubacterium limosum is dependent on the carbon and energy source

open access: yesMicrobial Biotechnology, 2021
Summary Eubacterium limosum KIST612 is one of the few acetogenic bacteria that has the genes encoding for butyrate synthesis from acetyl‐CoA, and indeed, E. limosum KIST612 is known to produce butyrate from CO but not from H2 + CO2.
Dennis Litty, Volker Müller
doaj   +1 more source

Evidence for proton-pump inhibitor (PPI)-associated dysbiosis in metabolically unhealthy obesity

open access: yesFrontiers in Endocrinology, 2023
Obesity adversely impacts millions of American adults by predisposing them to significant health risks and further complications. Obesity is differentiated into two groups: metabolically healthy and metabolically unhealthy.
Melissa A. Burmeister   +3 more
doaj   +1 more source

Novel role for the LKB1 pathway in controlling monocarboxylate fuel transporters [PDF]

open access: yes, 2008
A question preoccupying many researchers is how signal transduction pathways control metabolic processes and energy production. A study by Jang et al. (Jang, C., G. Lee, and J. Chung. 2008. J. Cell Biol.
Alessi, Dario R.   +1 more
core   +4 more sources

Conformable Device for Independent Measurements of Mucosal and Vascular Barriers in a Complex In Vitro Intestinal Model

open access: yesAdvanced Science, EarlyView.
Development of more complex in vitro models necessitates the development of improved monitoring approaches. This work demonstrates a novel conformable device capable of measuring the resistance of two cell barriers within a single model independently, a significant advantage over conventional trans‐epithelial/endothelial electrical resistance (TEER ...
Alexandra Elisabeth Wheeler   +7 more
wiley   +1 more source

Safety and efficacy of fluticasone propionate in the topical treatment of skin diseases [PDF]

open access: yes, 2004
Fluticasone propionate - the first carbothioate corticosteroid - has been classified as a potent anti-inflammatory drug for dermatological use. It is available as 0.05% cream and 0.005% ointment formulations for the acute and maintenance treatment of ...
Atsuta J   +33 more
core   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

open access: yesAdvanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang   +9 more
wiley   +1 more source

Butyrate Enhances Desensitization Induced by Oral Immunotherapy in Cow’s Milk Allergic Mice

open access: yesMediators of Inflammation, 2019
Background. In previous studies, we showed that a fructo-oligosaccharide- (FOS-) supplemented diet enhanced oral immunotherapy (OIT) efficacy in a mouse model for cow’s milk allergy. Fermentation of FOS by intestinal bacteria leads to production of short-
Marlotte M. Vonk   +8 more
doaj   +1 more source

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