Results 1 to 10 of about 303,050 (262)
PLoS ONE, 2012 Intracellular juxtamembrane regions of transmembrane proteins play pivotal roles in cell signalling, mediated by protein-protein interactions. Disordered protein regions, and short conserved motifs within them, are emerging as key determinants of many ...
Ilias Stavropoulos +5 more
doaj +3 more sources
Multi-pass, single-molecule nanopore reading of long protein strands
NatureThe ability to sequence single protein molecules in their native, full-length form would enable a more comprehensive understanding of proteomic diversity. Current technologies, however, are limited in achieving this goal1,2. Here, we establish a method for the long-range, single-molecule reading of intact protein strands on a commercial nanopore sensor
Miten Jain +2 more
exaly +3 more sources
Nuclear translocation of the 4-pass transmembrane protein Tspan8 [PDF]
Cell Research, 2021 Li Yu, Junjian Li, Hongxia Wang
exaly +3 more sources
Agriculture, 2021 Coffee is one of the main traded commodities worldwide, unfortunately, it generates massive amounts of by-products like coffee pulp (CoP), which could be utilized as an alternative feedstuff for cattle contributing to mitigate coffee production ...
Julieta Gertrudis Estrada-Flores +8 more
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Predicting protein functions with message passing algorithms [PDF]
Bioinformatics, 2004 Abstract Motivation: In the last few years, a growing interest in biology has been shifting toward the problem of optimal information extraction from the huge amount of data generated via large-scale and high-throughput techniques.
M. Leone, PAGNANI, ANDREA
openaire +4 more sources
EFFECT OF DIFFERENT HCl TREATMENTS ON RUMINAL DEGRADATION CHARACTERISTICS OF GROUND NUT CAKE [PDF]
Assiut Veterinary Medical Journal, 2008 The study was conducted to determine the effect of acid (HCl) treatment on ruminal degradation characteristics of dry matter (DM), crude protein (CP), and effective degradability of groundnut cake (GNC). GNC was either soaked in or sprayed with 0.5N HCl .
NIDAA. A.M., S.A. OMER, M.T. IBRAHIM
doaj +1 more source
An ER translocon for multi-pass membrane protein biogenesis [PDF]
eLife, 2020 Membrane proteins with multiple transmembrane domains play critical roles in cell physiology, but little is known about the machinery coordinating their biogenesis at the endoplasmic reticulum. Here we describe a ~ 360 kDa ribosome-associated complex comprising the core Sec61 channel and five accessory factors: TMCO1, CCDC47 and the Nicalin-TMEM147 ...
McGilvray, Philip T. +8 more
openaire +5 more sources
Profile of the single‐use, multiple‐pass protein A adsorber column in immunoadsorption [PDF]
Vox Sanguinis, 2021 AbstractBackground and ObjectivesImmunoadsorptions (IA) are used to remove autoantibodies from the plasma in autoimmune disorders. In this study, we evaluated the effects of a single‐use, recombinant staphylococcal protein A‐based immunoadsorber on blood composition of the patient.Materials and MethodsIn a cohort of patients with myasthenia gravis or ...
Nadine Schossee +10 more
openaire +2 more sources
Methods for Engineering Binders to Multi-Pass Membrane Proteins
Bioengineering, 2023 Numerous potential drug targets, including G-protein-coupled receptors and ion channel proteins, reside on the cell surface as multi-pass membrane proteins. Unfortunately, despite advances in engineering technologies, engineering biologics against multi-pass membrane proteins remains a formidable task.
Benjamin Thomas +2 more
openaire +3 more sources
EFFECT OF ESTIMATED BY-PASS PROTEIN LEVEL IN CONCENTRATED RATIONS ON PERFORMANCE OF LACTATING AWASSI EWES PRE -WEANING [PDF]
Mesopotamia Journal of Agriculture, 2013 This study was conducted in Al-Rashidiya animal breeding station, using 6 ewes (2-6 yrs old) with average body weight of 42.7 kg with their single new born lambs, the ewes divided into 3 groups just after 4th week of birth. Ewes and their lambs. The ewes
M. M. Kassem, M. N. Abdullah
doaj +1 more source