Results 1 to 10 of about 302,503 (164)

Protein disorder and short conserved motifs in disordered regions are enriched near the cytoplasmic side of single-pass transmembrane proteins.

open access: yesPLoS ONE, 2012
Intracellular juxtamembrane regions of transmembrane proteins play pivotal roles in cell signalling, mediated by protein-protein interactions. Disordered protein regions, and short conserved motifs within them, are emerging as key determinants of many ...
Ilias Stavropoulos   +5 more
doaj   +3 more sources

Effect of Increasing Supplementation Levels of Coffee Pulp on Milk Yield and Food Intake in Dual-Purpose Cows: An Alternative Feed Byproduct for Smallholder Dairy Systems of Tropical Climate Regions

open access: yesAgriculture, 2021
Coffee is one of the main traded commodities worldwide, unfortunately, it generates massive amounts of by-products like coffee pulp (CoP), which could be utilized as an alternative feedstuff for cattle contributing to mitigate coffee production ...
Julieta Gertrudis Estrada-Flores   +8 more
doaj   +1 more source

EFFECT OF DIFFERENT HCl TREATMENTS ON RUMINAL DEGRADATION CHARACTERISTICS OF GROUND NUT CAKE [PDF]

open access: yesAssiut Veterinary Medical Journal, 2008
The study was conducted to determine the effect of acid (HCl) treatment on ruminal degradation characteristics of dry matter (DM), crude protein (CP), and effective degradability of groundnut cake (GNC). GNC was either soaked in or sprayed with 0.5N HCl .
NIDAA. A.M., S.A. OMER, M.T. IBRAHIM
doaj   +1 more source

Profile of the single‐use, multiple‐pass protein A adsorber column in immunoadsorption [PDF]

open access: yesVox Sanguinis, 2021
AbstractBackground and ObjectivesImmunoadsorptions (IA) are used to remove autoantibodies from the plasma in autoimmune disorders. In this study, we evaluated the effects of a single‐use, recombinant staphylococcal protein A‐based immunoadsorber on blood composition of the patient.Materials and MethodsIn a cohort of patients with myasthenia gravis or ...
Nadine Schossee   +10 more
openaire   +2 more sources

Predicting protein functions with message passing algorithms [PDF]

open access: yesBioinformatics, 2004
Abstract Motivation: In the last few years, a growing interest in biology has been shifting toward the problem of optimal information extraction from the huge amount of data generated via large-scale and high-throughput techniques.
M. Leone, PAGNANI, ANDREA
openaire   +4 more sources

An ER translocon for multi-pass membrane protein biogenesis [PDF]

open access: yeseLife, 2020
Membrane proteins with multiple transmembrane domains play critical roles in cell physiology, but little is known about the machinery coordinating their biogenesis at the endoplasmic reticulum. Here we describe a ~ 360 kDa ribosome-associated complex comprising the core Sec61 channel and five accessory factors: TMCO1, CCDC47 and the Nicalin-TMEM147 ...
Philip T McGilvray   +8 more
openaire   +5 more sources

EFFECT OF ESTIMATED BY-PASS PROTEIN LEVEL IN CONCENTRATED RATIONS ON PERFORMANCE OF LACTATING AWASSI EWES PRE -WEANING [PDF]

open access: yesMesopotamia Journal of Agriculture, 2013
This study was conducted in Al-Rashidiya animal breeding station, using 6 ewes (2-6 yrs old) with average body weight of 42.7 kg with their single new born lambs, the ewes divided into 3 groups just after 4th week of birth. Ewes and their lambs. The ewes
M. M. Kassem, M. N. Abdullah
doaj   +1 more source

Identification of direct residue contacts in protein–protein interaction by message passing [PDF]

open access: yesProceedings of the National Academy of Sciences, 2009
Understanding the molecular determinants of specificity in protein–protein interaction is an outstanding challenge of postgenome biology. The availability of large protein databases generated from sequences of hundreds of bacterial genomes enables various statistical approaches to this problem. In this context covariance-based methods have been used to
Weigt, M.   +4 more
openaire   +3 more sources

Methods for Engineering Binders to Multi-Pass Membrane Proteins

open access: yesBioengineering, 2023
Numerous potential drug targets, including G-protein-coupled receptors and ion channel proteins, reside on the cell surface as multi-pass membrane proteins. Unfortunately, despite advances in engineering technologies, engineering biologics against multi-pass membrane proteins remains a formidable task.
Benjamin Thomas   +2 more
openaire   +3 more sources

Intra-Abdominal Lipopolysaccharide Clearance and Inactivation in Peritonitis: Key Roles for Lipoproteins and the Phospholipid Transfer Protein

open access: yesFrontiers in Immunology, 2021
IntroductionDuring peritonitis, lipopolysaccharides (LPS) cross the peritoneum and pass through the liver before reaching the central compartment. The aim of the present study was to investigate the role of lipoproteins and phospholipid transfer protein (
Maxime Nguyen   +37 more
doaj   +1 more source

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