Results 11 to 20 of about 60,574,786 (305)
Nature Chemical Biology, 2023 Traditional production of therapeutic secretory proteins often experiences delays between protein synthesis and therapeutic effects. An inducible protease-dependent protein secretion technique allows the immediate secretion of pre-translated biotherapeutic agents after exposure to chemical cues, tumor-specific antigens or photons.
Tianlu Wang, Yubin Zhou
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Predicting protein functions with message passing algorithms [PDF]
Bioinformatics, 2004 Abstract Motivation: In the last few years, a growing interest in biology has been shifting toward the problem of optimal information extraction from the huge amount of data generated via large-scale and high-throughput techniques.
M. Leone, PAGNANI, ANDREA
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An ER translocon for multi-pass membrane protein biogenesis [PDF]
eLife, 2020 Membrane proteins with multiple transmembrane domains play critical roles in cell physiology, but little is known about the machinery coordinating their biogenesis at the endoplasmic reticulum. Here we describe a ~ 360 kDa ribosome-associated complex comprising the core Sec61 channel and five accessory factors: TMCO1, CCDC47 and the Nicalin-TMEM147 ...
McGilvray, Philip T. +8 more
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Profile of the single‐use, multiple‐pass protein A adsorber column in immunoadsorption [PDF]
Vox Sanguinis, 2021 AbstractBackground and ObjectivesImmunoadsorptions (IA) are used to remove autoantibodies from the plasma in autoimmune disorders. In this study, we evaluated the effects of a single‐use, recombinant staphylococcal protein A‐based immunoadsorber on blood composition of the patient.Materials and MethodsIn a cohort of patients with myasthenia gravis or ...
Nadine Schossee +10 more
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Identification of direct residue contacts in protein–protein interaction by message passing [PDF]
Proceedings of the National Academy of Sciences, 2009 Understanding the molecular determinants of specificity in protein–protein interaction is an outstanding challenge of postgenome biology. The availability of large protein databases generated from sequences of hundreds of bacterial genomes enables various statistical approaches to this problem. In this context covariance-based methods have been used to
Weigt, M. +4 more
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Rumen bacterial community, indicators of reproduction and milk productivity at different levels of protein concentrate in the diets of dairy cows [PDF]
E3S Web of Conferences, 2021 The use of new sources of by-pass protein in the cow diets to optimize milk production and herd reproduction performance indicators in modern economic conditions is relevant.
Buryakov Nikolay +4 more
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Journal of Agricultural Sciences, 1996 Bu araştı rma ile, gebeliklerinin son 4. haftas ı ndaki koyunlar ı n, rumen parçalanabilirlikleri farkl ı protein kaynaklar ı kullan ı larak hazı rlanan yem karmalar ı ile beslehmesinin, kuzular ı n doğum ağı rl ı kları üzerindeki etkisi incelenmiştir ...
Şafak Polat +3 more
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NeuroImage, 2023 : Background: To investigate the association of ihMT (inhom signals with the demyelination and remyelination phases of the acute cuprizone mouse model in comparison with histology, and to assess the extent of tissue damage and repair from MRI data ...
Andreea Hertanu +12 more
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Evaluating nutrient degradation and degradation kinetics of some starch-rich cereal and legume grains in sheep consuming a starch-rich diet [PDF]
Journal of Central European AgricultureThis study aimed to determine the in-situ nutrient degradation and degradation kinetics of some starch-rich cereal and legume grains in sheep consuming diet containing high (32%) level of starch.
Şevket EVCİ, Mehmet KARSLI
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Viruses, 2021 Herpesviruses are large DNA viruses, which encode up to 300 different proteins including enzymes enabling efficient replication. Nevertheless, they depend on a multitude of host cell proteins for successful propagation.
Julia E. Hölper +11 more
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