Results 31 to 40 of about 60,574,786 (305)
Journal of Lipid Research, 1999 The isolated perfused mouse liver was utilized to evaluate the relative contribution of various molecules believed to participate in the removal of chylomicron remnants by the liver.
Kenneth C-W. Yu +3 more
doaj +1 more source
Message-passing algorithms for the prediction of protein domain interactions from protein–protein interaction data [PDF]
Bioinformatics, 2008 Abstract Motivation: Cellular processes often hinge upon specific interactions among proteins, and knowledge of these processes at a system level constitutes a major goal of proteomics. In particular, a greater understanding of protein–protein interactions can be gained via a more detailed investigation of the protein domain interactions
Mudassar Iqbal +3 more
openaire +4 more sources
Cell Reports, 2015 The membrane-spanning α helices of single-pass receptors play crucial roles in stabilizing oligomeric structures and transducing biochemical signals across the membrane.
Konstantin Knoblich +10 more
doaj +1 more source
You Shall Not Pass: MX2 Proteins Are Versatile Viral Inhibitors
Vaccines, 2023 Myxovirus resistance (MX) proteins are pivotal players in the innate immune response to viral infections. Less than 10 years ago, three independent groups simultaneously showed that human MX2 is an interferon (IFN)-stimulated gene (ISG) with potent anti-human immunodeficiency virus 1 (HIV-1) activity.
openaire +4 more sources
eLife, 2022 Secreted proteins, which include cytokines, hormones, and growth factors, are extracellular ligands that control key signaling pathways mediating cell-cell communication within and between tissues and organs.
Dirk H Siepe +6 more
doaj +1 more source
Membranome 3.0: Database of single‐pass membrane proteins with
Protein Science, 2022 AbstractThe Membranome database provides comprehensive structural information on single‐pass (i.e., bitopic) membrane proteins from six evolutionarily distant organisms, including protein–protein interactions, complexes, mutations, experimental structures, and models of transmembrane α‐helical dimers.
Andrei L. Lomize +6 more
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
ReumatismoObjective. Patients Acceptable Symptom State (PASS) is a single dichotomized question assessing health satisfaction. We aimed to investigate PASS achievement within 4 weeks of treatment with Janus kinase (JAK) inhibitors (Jakinibs) and its association ...
C. Garufi +11 more
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The Monkman Pass Highway Association : promoting the connecting link on coast-to-coast highway through the great Peace River country. [PDF]
, 1938 Nov. 7, 1938.
core
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source