Results 31 to 40 of about 633,410 (290)
eLife, 2022 Secreted proteins, which include cytokines, hormones, and growth factors, are extracellular ligands that control key signaling pathways mediating cell-cell communication within and between tissues and organs.
Dirk H Siepe +6 more
doaj +1 more source
Crystallization, preliminary crystallographic analysis and phasing of the thiosulfate-binding protein SoxY from Chlorobium limicola f. thiosulfatophilum [PDF]
, 2006 The 22 kDa SoxYZ protein complex from the green sulfur bacterium Chlorobium limicola f. thiosulfatophilum is a central player in the sulfur-oxidizing (Sox) enzyme system of the organism by activating thiosulfate for oxidation by SoxXA and SoxB.
Stout, Jan +5 more
core +1 more source
Pass-back chain extension expands multimodular assembly line biosynthesis. [PDF]
, 2020 Modular nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS) enzymatic assembly lines are large and dynamic protein machines that generally effect a linear sequence of catalytic cycles.
Huan, Tao +5 more
core
Benchmarking subcellular localization and variant tolerance predictors on membrane proteins
BMC Genomics, 2019 Background Membrane proteins constitute up to 30% of the human proteome. These proteins have special properties because the transmembrane segments are embedded into lipid bilayer while extramembranous parts are in different environments.
Tommaso Orioli, Mauno Vihinen
doaj +1 more source
Communicability betweenness in complex networks [PDF]
, 2009 Betweenness measures provide quantitative tools to pick out fine details from the massive amount of interaction data that is available from large complex networks.
Estrada, Ernesto +2 more
core +2 more sources
ReumatismoObjective. Patients Acceptable Symptom State (PASS) is a single dichotomized question assessing health satisfaction. We aimed to investigate PASS achievement within 4 weeks of treatment with Janus kinase (JAK) inhibitors (Jakinibs) and its association ...
C. Garufi +11 more
doaj +1 more source
Dose dependent toxicity of glutamic acid: a review
International Journal of Food Properties, 2020 L-glutamate, the major neurotransmitter in humans, becomes excitotoxic when present outside of protein in excess of what the healthy human was designed to accommodate; amounts readily available to consumers who ingest multiple free-glutamate-containing ...
Adrienne Samuels
doaj +1 more source
Na+/Ca2+ selectivity in the bacterial voltage-gated sodium channel NavAb [PDF]
PeerJ, 2013 The recent publication of a number of high resolution bacterial voltage-gated sodium channel structures has opened the door for the mechanisms employed by these channels to distinguish between ions to be elucidated.
Ben Corry
doaj +2 more sources
A gas-liquid solid phase peptide and protein sequenator [PDF]
, 1981 A new miniaturized protein and peptide sequenator has been constructed which uses gas phase reagents at the coupling and cleavage steps of the Edman degradation. The sample is embedded in a matrix of Polybrene dried onto a porous glass fiber disc located
Dreyer, William J. +3 more
core
The architecture of the protein domain universe [PDF]
, 2004 Understanding the design of the universe of protein structures may provide insights into protein evolution. We study the architecture of the protein domain universe, which has been found to poses peculiar scale-free properties (Dokholyan et al., Proc ...
Dokholyan, Nikolay V.
core +4 more sources