Results 21 to 30 of about 303,050 (262)

One of the Triple Poly(A) Signals in the M112-113 Gene Is Important and Sufficient for Stabilizing the M112-113 mRNA and the Replication of Murine Cytomegalovirus

open access: yesViruses, 2020
The M112-113 gene is the first early gene of the murine cytomegalovirus (MCMV), and its expression is activated by the immediate-early 3 (IE3) protein during MCMV infection in permissive cells.
Ruth Cruz-cosme   +2 more
doaj   +1 more source

Produksi NH3, Protein By Pass dan Sintesis Protein Mikroba dari Pod Kakao yang di Suplementasi Chromolaena odorata

open access: yesJurnal Peternakan Indonesia, 2015
Penyediaan pakan alternatif merupakan tantangan utama bagi peternak ketika pakan hijauan semakin berkurang, diantaranya pod kakao. Supaya dapat dimanfaatkan secara optimal, maka pod kakao perlu disuplementasi dengan Chromolaena odorata.
A. Dona, H. D. Triani
doaj   +1 more source

Invariant point message passing for protein side chain packing

open access: yesProteins: Structure, Function, and Bioinformatics, 2023
Abstract Protein side chain packing (PSCP) is a fundamental problem in the field of protein engineering, as high‐confidence and low‐energy conformations of amino acid side chains are crucial for understanding (and designing) protein folding, protein–protein interactions, and protein‐ligand interactions.
Nicholas Z. Randolph, Brian Kuhlman
openaire   +3 more sources

Evolution and adaptation of single-pass transmembrane proteins

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2018
A comparative analysis of 6039 single-pass (bitopic) membrane proteins from six evolutionarily distant organisms was performed based on data from the Membranome database. The observed repertoire of bitopic proteins is significantly enlarged in eukaryotic cells and especially in multicellular organisms due to the diversification of enzymes, emergence of
Irina D, Pogozheva, Andrei L, Lomize
openaire   +2 more sources

Intrinsic Disorder in Transmembrane Proteins: Roles in Signaling and Topology Prediction. [PDF]

open access: yesPLoS ONE, 2016
Intrinsically disordered regions (IDRs) are peculiar stretches of amino acids that lack stable conformations in solution. Intrinsic Disorder containing Proteins (IDP) are defined by the presence of at least one large IDR and have been linked to multiple ...
Jérôme Bürgi   +3 more
doaj   +1 more source

Constitutive cleavage of the single-pass transmembrane protein alcadeinα prevents aberrant peripheral retention of Kinesin-1. [PDF]

open access: yesPLoS ONE, 2012
Various membrane proteins are shed by proteinases, constitutively and/or when stimulated by external signals. While the physiological significance of external signal-induced cleavages has been intensely investigated, relatively little is known about the ...
Chiaki Maruta   +5 more
doaj   +1 more source

Carcass and meat quality of “Leccese” breed lambs suckling from ewes fed diets containing vegetable by-pass protein

open access: yesItalian Journal of Animal Science, 2011
It is considered necessary to supplement the majority of dietary proteins for the rearing of goats and sheep (Pulina et al., 1990; Robinson, 1987). In ruminants, 70 % of protein requirement is satisfied by cytoplasmic synthesised protein, while the ...
A. Tateo, P. Centoducati
doaj   +1 more source

The unfolded protein response in glioblastomas: passing the stress test [PDF]

open access: yesCNS Oncology, 2013
469 ISSN 2045-0907 10.2217/CNS.13.50 © 2013 Future Medicine Ltd CNS Oncol. (2013) 2(6), 469–472 One may think of tumors as existentially stressed; their rapid, uncontrolled proliferation in the midst of unstable blood supplies results in a hypoxic, nutrient-deprived environment, and the threat of immune system attack is almost constant (if ineffective).
openaire   +2 more sources

Evaluation of the components of the chylomicron remnant removal mechanism by use of the isolated perfused mouse liver

open access: yesJournal of Lipid Research, 1999
The isolated perfused mouse liver was utilized to evaluate the relative contribution of various molecules believed to participate in the removal of chylomicron remnants by the liver.
Kenneth C-W. Yu   +3 more
doaj   +1 more source

Transmembrane Complexes of DAP12 Crystallized in Lipid Membranes Provide Insights into Control of Oligomerization in Immunoreceptor Assembly

open access: yesCell Reports, 2015
The membrane-spanning α helices of single-pass receptors play crucial roles in stabilizing oligomeric structures and transducing biochemical signals across the membrane.
Konstantin Knoblich   +10 more
doaj   +1 more source

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