Results 21 to 30 of about 633,410 (290)

Intrinsic Disorder in Transmembrane Proteins: Roles in Signaling and Topology Prediction. [PDF]

open access: yesPLoS ONE, 2016
Intrinsically disordered regions (IDRs) are peculiar stretches of amino acids that lack stable conformations in solution. Intrinsic Disorder containing Proteins (IDP) are defined by the presence of at least one large IDR and have been linked to multiple ...
Jérôme Bürgi   +3 more
doaj   +1 more source

The coagulation of myosin in muscle [PDF]

open access: yes, 1937
The coagulation of myosin is one of the few changes in the proteins of muscle known to take place during contraction and rigor. Although under certain conditions as much as one-third of the total protein of muscle may become insoluble, the significance ...
Mirsky, A. E.
core   +2 more sources

Constitutive cleavage of the single-pass transmembrane protein alcadeinα prevents aberrant peripheral retention of Kinesin-1. [PDF]

open access: yesPLoS ONE, 2012
Various membrane proteins are shed by proteinases, constitutively and/or when stimulated by external signals. While the physiological significance of external signal-induced cleavages has been intensely investigated, relatively little is known about the ...
Chiaki Maruta   +5 more
doaj   +1 more source

SChloro: directing Viridiplantae proteins to six chloroplastic sub-compartments [PDF]

open access: yes, 2016
Motivation: Chloroplasts are organelles found in plants and involved in several important cell processes. Similarly to other compartments in the cell, chloroplasts have an internal structure comprising several sub-compartments, where different proteins ...
Casadio, Rita   +3 more
core   +2 more sources

Protein disorder and short conserved motifs in disordered regions are enriched near the cytoplasmic side of single-pass transmembrane proteins.

open access: yesPLoS ONE, 2012
Intracellular juxtamembrane regions of transmembrane proteins play pivotal roles in cell signalling, mediated by protein-protein interactions. Disordered protein regions, and short conserved motifs within them, are emerging as key determinants of many ...
Ilias Stavropoulos   +5 more
doaj   +1 more source

Virulence- and signaling-associated genes display a preference for long 3′UTRs during rice infection and metabolic stress in the rice blast fungus [PDF]

open access: yes, 2019
Generation of mRNA isoforms by alternative polyadenylation (APA) and their involvement in regulation of fungal cellular processes, including virulence, remains elusive.
Demuez, Marie   +5 more
core   +1 more source

Evaluation of the components of the chylomicron remnant removal mechanism by use of the isolated perfused mouse liver

open access: yesJournal of Lipid Research, 1999
The isolated perfused mouse liver was utilized to evaluate the relative contribution of various molecules believed to participate in the removal of chylomicron remnants by the liver.
Kenneth C-W. Yu   +3 more
doaj   +1 more source

Islands of linkage in an ocean of pervasive recombination reveals two-speed evolution of human cytomegalovirus genomes [PDF]

open access: yes, 2016
Human cytomegalovirus (HCMV) infects most of the population worldwide, persisting throughout the host's life in a latent state with periodic episodes of reactivation.
Atkinson, Claire   +18 more
core   +1 more source

Transmembrane Complexes of DAP12 Crystallized in Lipid Membranes Provide Insights into Control of Oligomerization in Immunoreceptor Assembly

open access: yesCell Reports, 2015
The membrane-spanning α helices of single-pass receptors play crucial roles in stabilizing oligomeric structures and transducing biochemical signals across the membrane.
Konstantin Knoblich   +10 more
doaj   +1 more source

Green fluorescent protein as an indicator of cryoinjury in tissues. [PDF]

open access: yes, 2013
The fluorescence intensity of Green Fluorescent Protein (GFP) has previously been demonstrated to be an accurate indicator of cellular viability following cryoinsult in individual GFP-transfected cells. In an attempt to ascertain whether GFP fluorescence
Aguilar, Guillermo   +3 more
core   +1 more source

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