Results 31 to 40 of about 7,255 (192)

c-di-GMP modulates type IV MSHA pilus retraction and surface attachment in Vibrio cholerae. [PDF]

, 2020
Biofilm formation by Vibrio cholerae facilitates environmental persistence, and hyperinfectivity within the host. Biofilm formation is regulated by 3',5'-cyclic diguanylate (c-di-GMP) and requires production of the type IV mannose-sensitive hemagglutinin
Biais, Nicolas, Brun, Yves V, Campos-Gomez, Javier, Chlebek, Jennifer L, Crair, Benjamin, Dalia, Ankur B, Ellison, Courtney K, Farhat, Ali M, Floyd, Kyle A, Hughes, Hannah Q, Hwan Park, Jin, Lee, Calvin K, Liu, Jun, Lomba, Charles J, Nametalla, Mahmoud, Valentine, Aneesa, Wong, Gerard CL, Wu, Daniel C, Xian, Wujing, Yildiz, Fitnat H, Zhu, Shiwei   +20 more
core   +2 more sources

Cyclic di-GMP: second messenger extraordinaire [PDF]

, 2017
Cyclic dinucleotides (CDNs) are highly versatile signalling molecules that control various important biological processes in bacteria. The best-studied example is cyclic di-GMP (c-di-GMP).
Jenal, Urs, Lori, Christian, Reinders, Alberto   +2 more
core   +1 more source

Responses to elevated c-di-GMP levels in mutualistic and pathogenic plant-interacting bacteria. [PDF]

PLoS ONE, 2014
Despite a recent burst of research, knowledge on c-di-GMP signaling pathways remains largely fragmentary and molecular mechanisms of regulation and even c-di-GMP targets are yet unknown for most bacteria.
Daniel Pérez-Mendoza, Isabel M Aragón, Harold A Prada-Ramírez, Lorena Romero-Jiménez, Cayo Ramos, María-Trinidad Gallegos, Juan Sanjuán   +6 more
doaj   +1 more source

Cyclic di-GMP regulates bacterial colonization and further biocontrol efficacy of Bacillus velezensis against apple ring rot disease via its potential receptor YdaK

Frontiers in Microbiology, 2022
Bacillus species are among the most investigated beneficial bacteria and widely used in agricultural systems as biological control agents. Its biocontrol efficacy is controlled by diverse regulators.
Huiling Gong, Wenxiao Jiang, Yang Yang, Yue Zhang, Xufei Chen, Wei Li, Panlei Yang, Zhenshuo Wang, Qi Wang, Yan Li   +9 more
doaj   +1 more source

Regulation of Protein Secretion Systems Mediated by Cyclic Diguanylate in Plant-Interacting Bacteria [PDF]

, 2019
The ubiquitous second messenger cyclic diguanylate (c-di-GMP) is involved in the regulation of different processes in bacteria. In phytopathogens, intracellular fluctuations in the concentration of this molecule contribute to the lifestyle switching from
López Baena, Francisco Javier, Medina Morillas, Carlos, Vinardell González, José María   +2 more
core   +1 more source

Identification and Characterization of c-di-GMP Metabolic Enzymes of Leptospira interrogans and c-di-GMP Fluctuations After Thermal Shift and Infection

Frontiers in Microbiology, 2018
Leptospirosis is a widespread zoonotic disease caused by pathogenic Leptospira species. The most common species, Leptospira interrogans, can transfer from contaminated soil or water to the human body.
Guohui Xiao, Liangliang Kong, Liangliang Kong, Rongbo Che, Yusi Yi, Qinchao Zhang, Jie Yan, Jie Yan, Xu'ai Lin, Xu'ai Lin   +9 more
doaj   +1 more source

c-di-GMP regulates bacterial NAD biosynthesis via targeting the transcriptional repressor NadR

mBio
As a near-ubiquitous bacterial second messenger, cyclic di-GMP (c-di-GMP) regulates a multitude of important biological processes. The regulatory effects of c-di-GMP on bacterial physiological processes are mediated through its interaction with various ...
Lianying Mao, Jialin Li, Xinyi Huo, Wenguang Yang, Heng Zhang, Chongyi Duan, Xihui Shen, Lei Zhang   +7 more
doaj   +1 more source

CRP-Like Transcriptional Regulator MrpC Curbs c-di-GMP and 3′,3′-cGAMP Nucleotide Levels during Development in Myxococcus xanthus

mBio, 2022
Myxococcus xanthus has a nutrient-regulated biphasic life cycle forming predatory swarms in the presence of nutrients and spore-filled fruiting bodies in the absence of nutrients.
Sofya Kuzmich, Patrick Blumenkamp, Doreen Meier, Dobromir Szadkowski, Alexander Goesmann, Anke Becker, Lotte Søgaard-Andersen   +6 more
doaj   +1 more source

Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre [PDF]

, 2014
Bis-(3′,5′) cyclic di-guanylate (c-di-GMP) is a key bacterial second messenger that is implicated in the regulation of many crucial processes that include biofilm formation, motility and virulence.
An, Shi-Qi, Bellini, Dom, Bumann, Mario, Caly, Delphine L., Dow, J. Maxwell, McCarthy, Yvonne, Ryan, Robert P., Walsh, Martin A.   +7 more
core   +3 more sources

Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases [PDF]

, 2017
The bacterial second messenger cyclic di-3′,5′-guanosine monophosphate (c-di-GMP) is a key regulator of bacterial motility and virulence. As high levels of c-di-GMP are associated with the biofilm lifestyle, c-di-GMP hydrolysing phosphodiesterases (PDEs)
A Deepthi, A Sundriyal, A Tchigvintsev, A Ueda, A Vagin, A Winkler, AD Tischler, AD Tischler, AJ Schmidt, B Huang, BW Holloway, C Chan, C Romier, CD Boyd, CW Phippen, D Balasubramanian, D Bellini, DA D’Argenio, DJ Hosfield, DL Caly, EF Pettersen, F Rao, F Rao, G Kuppuraj, G Minasov, G Winter, G Winter, GL Winsor, GN Murshudov, H Ceri, H Kulasakara, H Zheng, I Ivanov, ID Hay, J Robert-Paganin, JH Merritt, K Syson, K-H Choi, KD Miner, KM Thormann, M Christen, M Valentini, M Vorachit, MD Winn, MVAS Navarro, MY Galperin, N Barraud, O Kirillina, P Aldridge, P Emsley, P Evans, PD Newell, PR Evans, R Donlan, R Paul, R Simm, R Tamayo, RM Keegan, RP Ryan, RP Ryan, RZ Liao, TRM Barends, TT Hoang, U Römling, V Stelitano, VB Chen, W Grzybkowski, W Kabsch, Y Li, Y Qi, Y Wang   +70 more
core   +2 more sources