Copper-catalyzed asymmetric sp3 C–H arylation of tetrahydroisoquinoline mediated by a visible light photoredox catalyst [PDF]
Beilstein Journal of Organic Chemistry, 2016 This report describes a highly enantioselective oxidative sp3 C–H arylation of N-aryltetrahydroisoquinolines (THIQs) through a dual catalysis platform. The combination of the photoredox catalyst, [Ir(ppy)2(dtbbpy)]PF6, and chiral copper catalysts provide
Pierre Querard +3 more
doaj +5 more sources
A Generalized Approach for Distal C–H Arylation of Organic Building Blocks: Unveiling the Role of Counter Anion [PDF]
Advanced ScienceAryl–aryl coupling at remote C–H sites remain a formidable challenge in organic synthesis, particularly for electronically biased arenes and heteroarenes.
Jagrit Grover +6 more
doaj +2 more sources
Expanding chemical space by para-C−H arylation of arenes [PDF]
Nature Communications, 2022 Biaryls are privileged structural motif used in the discovery and design of therapeutics with high affinity and specificity for a broad range of protein targets.
Sudip Maiti +7 more
doaj +2 more sources
Traditional and sustainable approaches for the construction of C–C bonds by harnessing C–H arylation [PDF]
Nature Communications, 2022 Transition-metal-catalyzed C–H arylations are an effective tool for the construction of biaryl motifs in an efficient and selective manner. Here the authors provide an overview of the state-of-the-art of the field and perspectives on emerging directions ...
Jagrit Grover +3 more
doaj +2 more sources
Synthesis of Novel 3,6-Dithienyl Diketopyrrolopyrrole Dyes by Direct C-H Arylation [PDF]
Molecules, 2020 Direct C-H arylation coupling is potentially a more economical and sustainable process than conventional cross-coupling. However, this method has found limited application in the synthesis of organic dyes for dye-sensitized solar cells. Although direct C-
Amsalu Efrem Yemene +4 more
doaj +2 more sources
Copper-catalyzed remote C–H arylation of polycyclic aromatic hydrocarbons (PAHs) [PDF]
Beilstein Journal of Organic Chemistry, 2020 The regioselective C–H arylation of substituted polycyclic aromatic hydrocarbons (PAHs) is a desired but challenging task. A copper-catalyzed C7–H arylation of 1-naphthamides has been developed by using aryliodonium salts as arylating reagents.
Anping Luo +5 more
doaj +2 more sources
Enantioselective Rh(I)-Catalyzed C–H Arylation of Ferroceneformaldehydes [PDF]
ACS Central Science, 2023 Chen-Xu Liu +3 more
doaj +2 more sources
Regioselective Stepwise Synthesis of Unsymmetrical 1,2,5-Triarylpyrroles via Palladium-Catalyzed Decarboxylative Cross-Coupling and C–H Arylation [PDF]
MoleculesPyrrole derivatives are natural organic molecules that are important to the pharmaceutical industry due to their occurrence in nature and their use in a wide range of medical applications. In general, non-symmetric, 1,2,5-triaryl-substituted pyrroles are
Cindy Buonomano +6 more
doaj +2 more sources
Transition Metal‐Driven Selectivity in Direct C−H Arylation of Imidazo[2,1‐b]Thiazole [PDF]
ChemistryOpenA selective direct arylation of the different Csp2‐H bonds of imidazo[2,1‐b]thiazole with (hetero) aryl halides can be achieved simply by switching from a palladium catalyst system to the use of stoichiometric amounts of copper. The observed selectivity,
Dr. Antonio Del Vecchio +9 more
doaj +2 more sources
Synthesis of Planar Chiral Ferroceneformaldehydes via Rh(I)-Catalyzed C–H Arylation [PDF]
ACS Central Science, 2023 Hailey Hendricks, Jose. B. Roque
doaj +2 more sources