Results 31 to 40 of about 206,495 (234)

Strategies to transform remote C(sp3)-H bonds of amino acid derivatives

open access: yesTetrahedron Chem, 2022
Amino acids and peptides play an important role in nature as well as in the pharmaceutical industry. Therefore, transformation of amino acids and peptides into their unnatural derivatives via step and atom economical ways is highly demanding. Although, a
Supreeta Sen   +2 more
doaj   +1 more source

A first example of cobalt-catalyzed remote C-H functionalization of 8-aminoquinolines operating through a single electron transfer mechanism [PDF]

open access: yes, 2016
The development of new C[BOND]H functionalization protocols based on inexpensive cobalt catalysts is currently attracting significant interest. Functionalized 8-aminoquinoline compounds are high-potential building blocks in organic chemistry and ...
Ackermann   +49 more
core   +1 more source

Transition-metal-catalyzed aromatic C–H functionalization assisted by the phosphorus-containing directing groups

open access: yesGreen Synthesis and Catalysis, 2023
Transition-metal-catalyzed C–H bond functionalization has attracted tremendous attention as an increasingly important protocol for the construction of C–C and C–X bonds.
Jian Zhang   +5 more
doaj   +1 more source

C-H Functionalization via Iron-Catalyzed Carbene-Transfer Reactions

open access: yesMolecules, 2020
The direct C-H functionalization reaction is one of the most efficient strategies by which to introduce new functional groups into small organic molecules.
Claire Empel   +2 more
doaj   +1 more source

Efficient direct 2,2,2-trifluoroethylation of indoles via C-H functionalization [PDF]

open access: yes, 2015
A novel highly C3 selective metal free trifluoroethylation of indoles using 2,2,2-trifuoroethyl(mesityl)-iodonium triflate was developed. The methodology enables the introduction of a trifluoroethyl group in a fast and efficient reaction under mild ...
Bihari, Tamás   +7 more
core   +1 more source

Copper-Catalyzed Regioselective Ortho C-H Cyanation of Vinylarenes [PDF]

open access: yes, 2014
A copper-based catalytic technique for the regioselective ortho C-H cyanation of vinylarenes has been developed. This method provides an effective means for the selective functionalization of vinylarene derivatives.
Albrecht   +50 more
core   +1 more source

KI-H2O2 promoted intramolecular oxidative CH Functionalization: Synthesis of Benzo[d]thiazol-2-amines

open access: yesResults in Chemistry, 2022
This work reported a novel, efficient and green technique for the synthesis of N-substituted benzothiazoles using KI/H2O2 in DCM via intramolecular oxidative CH functionalization was carried out.
Manish M. Katiya   +2 more
doaj   +1 more source

Exo-hydrogenated Single Wall Carbon Nanotubes

open access: yes, 2001
An extensive first-principles study of fully exo-hydrogenated zigzag (n,0) and armchair (n,n) single wall carbon nanotubes (C$_n$H$_n$), polyhedral molecules including cubane, dodecahedrane, and C$_{60}$H$_{60}$ points to crucial differences in the ...
A.C. Dillon   +29 more
core   +2 more sources

Synthesis and late-stage functionalization of complex molecules through C-H fluorination and nucleophilic aromatic substitution. [PDF]

open access: yes, 2014
We report the late-stage functionalization of multisubstituted pyridines and diazines at the position α to nitrogen. By this process, a series of functional groups and substituents bound to the ring through nitrogen, oxygen, sulfur, or carbon are ...
Fier, Patrick S, Hartwig, John F
core   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

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