Strategies to transform remote C(sp3)-H bonds of amino acid derivatives
Amino acids and peptides play an important role in nature as well as in the pharmaceutical industry. Therefore, transformation of amino acids and peptides into their unnatural derivatives via step and atom economical ways is highly demanding. Although, a
Supreeta Sen +2 more
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Efficient direct 2,2,2-trifluoroethylation of indoles via C-H functionalization [PDF]
A novel highly C3 selective metal free trifluoroethylation of indoles using 2,2,2-trifuoroethyl(mesityl)-iodonium triflate was developed. The methodology enables the introduction of a trifluoroethyl group in a fast and efficient reaction under mild ...
Bihari, Tamás +7 more
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Transition-metal-catalyzed C–H bond functionalization has attracted tremendous attention as an increasingly important protocol for the construction of C–C and C–X bonds.
Jian Zhang +5 more
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A first example of cobalt-catalyzed remote C-H functionalization of 8-aminoquinolines operating through a single electron transfer mechanism [PDF]
The development of new C[BOND]H functionalization protocols based on inexpensive cobalt catalysts is currently attracting significant interest. Functionalized 8-aminoquinoline compounds are high-potential building blocks in organic chemistry and ...
Ackermann +49 more
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C-H Functionalization via Iron-Catalyzed Carbene-Transfer Reactions
The direct C-H functionalization reaction is one of the most efficient strategies by which to introduce new functional groups into small organic molecules.
Claire Empel +2 more
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Copper-Catalyzed Regioselective Ortho C-H Cyanation of Vinylarenes [PDF]
A copper-based catalytic technique for the regioselective ortho C-H cyanation of vinylarenes has been developed. This method provides an effective means for the selective functionalization of vinylarene derivatives.
Albrecht +50 more
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Triorganoindium reagents in Rh-catalyzed C–H activation/C–C cross-coupling reactions of 2-arylpyridines [PDF]
[Abstract] The activation of C–H bonds through catalytic reactions using transition metals is an important challenge in organic chemistry in which the intermediates are related to those produced in the classical cross-coupling reactions.
Pérez Sestelo, José +3 more
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Exo-hydrogenated Single Wall Carbon Nanotubes
An extensive first-principles study of fully exo-hydrogenated zigzag (n,0) and armchair (n,n) single wall carbon nanotubes (C$_n$H$_n$), polyhedral molecules including cubane, dodecahedrane, and C$_{60}$H$_{60}$ points to crucial differences in the ...
A.C. Dillon +29 more
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Site-Selective Functionalization of (sp3 )C-H Bonds Catalyzed by Artificial Metalloenzymes Containing an Iridium-Porphyrin Cofactor. [PDF]
The selective functionalization of one C-H bond over others in nearly identical steric and electronic environments can facilitate the construction of complex molecules.
Clark, Douglas S +4 more
core +3 more sources
Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li +6 more
wiley +1 more source

