Radical Advances in C(sp3)−H Functionalization: Foundations for C–H Cross-Coupling [PDF]
, 2022 C−H functionalization reactions are playing an increasing role in the preparation and modification of complex organic molecules, including pharmaceuticals, agrochemicals, and polymer precursors.
Dung, Golden +2 more
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Arenes and Heteroarenes C–H Functionalization Under Enabling Conditions: Electrochemistry, Photoelectrochemistry & Flow Technology [PDF]
, 2023 C-H bond functionalization generates molecular complexity in single-step transformation. However, the activation of C-H bonds requires expensive metals or stoichiometric amounts of oxidizing/reducing species.
Ayesha , Murtaza +6 more
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Imine as a Linchpin Approach for Distal C(sp2)–H Functionalization [PDF]
, 2020 Despite the widespread applications of C–H functionalization, controlling site selectivity remains a significant challenge. Covalently attached directing group (DG) served as an ancillary ligand to ensure proximal ortho-, distal meta- and para-C-H ...
Sadhan, Jana +6 more
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Isodesmic C–H Functionalization: Carboxyl-Assisted Remote meta- and ortho-C–H Iodination of Arenes via Shuttle Catalysis [PDF]
, 2021 Isodesmic C–H functionalization reactions are extremely rare. Herein we report the first Pd(II)-catalyzed isodesmic C–H iodination of arenes using 2-nitrophenyl iodides as the mild iodinating reagents.
Lei, Cai +7 more
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C–H bond functionalization reactions enabled by photobiocatalytic cascades
Green Synthesis and Catalysis, 2021 Light may participate in biocatalytic processes either by direct light-induced biocatalysis or by cascading light-induced chemical reactions with biocatalytic ones, which are acknowledged as photocatalysis.
Yuanying Li +3 more
doaj +1 more source
Tuning Benzylic C−H Functionalization of (Thio)xanthenes with Electrochemistry
Molecules, 2023 Here, we report a tunable electrochemical benzylic C−H functionalization of (thio)xanthenes with terminal alkynes and nitriles in the absence of any catalyst or external chemical oxidant.
Changji Wang +4 more
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Organophotoredox-Catalyzed Direct C-H Functionalization of “Drug Prejudice” at Room Temperature [PDF]
, 2020 Organophotocatalytic C─H bond functionalization has attracted lot of attention in the past several years due to the possibility of catalysing reactions in a metal-free environment.
Narendra, Chaubey +2 more
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Recent advances in transition-metal-free C–H functionalization of imidazo[1,2-a]pyridines
Green Synthesis and Catalysis, 2022 Imidazo[1,2-a]pyridines are unique nitrogen-containing organic compounds with wide applications in pharmaceuticals, natural products, material science and organometallics.
Linlin Shi, Tiantian Li, Guang-Jian Mei
doaj +1 more source
Catalytic Intermolecular Functionalization of Benzimidazoles [PDF]
, 2019 This chapter describes contemporary strategies for selective catalytic intermolecular functionalization of the benzimidazole scaffold. Functionalization at nitrogen and position C-2 is well developed employing copper, palladium, rhodium, nickel, and ...
Fjellaksel, Richard +3 more
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Catalyst-Controlled C–H Functionalization of Adamantanes Using Selective H‑Atom Transfer [PDF]
, 2018 A method for the direct functionalization of diamondoids has been developed using photoredox and H atom transfer catalysis. This C–H alkylation reaction has excellent chemoselectivity for the strong 3° C–H bonds of adamantanes in polyfunctional molecules.
Abigail Feceu (5237030) +11 more
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