Stereoselective C−B and C−H Bonds Functionalization of polyBorylated Alkenes [PDF]
, 2023 Alkenes are fundamental functional groups which feature in various materials and bioactive molecules; however, efficient divergent strategies for their stereodefined synthesis are difficult.
Narendra K., Vaishanv +3 more
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Transition-metal-free electrochemical-induced active C(sp3)-H functionalization
Green Chemistry Letters and Reviews, 2023 Direct C–H bond functionalization is the most effective technique to construct C–X (X = C, N, O, S, etc.), which could simplify the conventional synthesis methods.
Xiaolong Ma +4 more
doaj +1 more source
Radical‐Promoted Distal C‐H Functionalization of C(sp3) Centers with Fluorinated Moieties
, 2020 International audienceDue to their unique properties, fluorinated scaffolds are pivotal compounds in pharmaceuticals, agrochemicals and materials science.
Tatiana Besset +5 more
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Multitask Prediction of Site Selectivity in Aromatic C-H Functionalization Reactions [PDF]
, 2019 Aromatic C-H functionalization reactions are an important part of the synthetic chemistry toolbox. Accurate prediction of site selectivity can be crucial for prioritizing target compounds and synthetic routes in both drug discovery and process chemistry.
Klavs F. Jensen (5815258) +8 more
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Enantioselective Single and Dual a-C–H Bond Functionalization of Cyclic Amines via Enzymatic Carbene Transfer [PDF]
, 2022 Cyclic amines are ubiquitous structural motifs found in pharmaceuticals and biologically active natural products, making methods for their elaboration via direct C–H functionalization of considerable synthetic value.
Bo M. , Couture +5 more
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Strategies to transform remote C(sp3)-H bonds of amino acid derivatives
Tetrahedron Chem, 2022 Amino acids and peptides play an important role in nature as well as in the pharmaceutical industry. Therefore, transformation of amino acids and peptides into their unnatural derivatives via step and atom economical ways is highly demanding. Although, a
Supreeta Sen +2 more
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Organocatalytic Asymmetric α-C-H Functionalization of Alkyl Amines [PDF]
, 2023 Catalytic enantioselective α-C–H functionalization of achiral amines could provide an ideal synthetic approach toward chiral amines. The alkyl amines constitute the most diverse and synthetically important class of achiral amines.
Cheng, Cheng +9 more
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C-H Functionalization Reactions of Unprotected N-Heterocycles by Gold Catalyzed Carbene Transfer [PDF]
, 2020 The C-H functionalization reaction of N-heterocycles with unprotected N-H group is one of the most step-economic strategies to introduce functional groups without the need of installation and removal of protecting groups.
Polina, Aseeva +5 more
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Use of Emerging C–H Functionalization Methods to Implement Strategies for the Divergent Total Syntheses of Bridged Polycyclic Natural Products [PDF]
, 2023 Carbon–hydrogen (C–H) bonds are ubiquitous in complex natural products. Over the past three decades, many methods to convert C–H bonds distal from functional groups, which were generally considered inert, have been developed.
Richmond, Sarpong, Goh, Sennari
core +1 more source
C-H Functionalization via Iron-Catalyzed Carbene-Transfer Reactions
Molecules, 2020 The direct C-H functionalization reaction is one of the most efficient strategies by which to introduce new functional groups into small organic molecules.
Claire Empel +2 more
doaj +1 more source