Results 21 to 30 of about 6,068,014 (260)
Recent Advances on Synthetic Methodology Merging C–H Functionalization and C–C Cleavage
Molecules, 2020 The functionalization of C–H bonds has become a major thread of research in organic synthesis that can be assessed from different angles, for instance depending on the type of catalyst employed or the overall transformation that is carried out.
Hamid Azizollahi +1 more
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Ru-Catalyzed Selective C–H Functionalization of Pyridotriazoles with Acrylates
SynOpen, 2021 Ruthenium-catalyzed efficient and selective C–H alkenylation of pyridotriazoles with acrylates is described. The combination of metals (Ru and Fe) plays a crucial role in achieving quantitative yields of the desired products.
Abhisek Joshi +2 more
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When metal-catalyzed C–H functionalization meets visible-light photocatalysis
Beilstein Journal of Organic Chemistry, 2020 While aiming at sustainable organic synthesis, over the last decade particular attention has been focused on two modern fields, C–H bond activation, and visible-light-induced photocatalysis.
Lucas Guillemard, Joanna Wencel-Delord
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Photoredox C–H functionalization leads the site-selective phenylalanine bioconjugation
Scientific Reports, 2022 Site-selectively chemical bioconjugation of peptides and proteins can improve the therapeutic exploration of modified protein drugs. Only 3.8% natural abundance of phenylalanine in protein and nearly 90% of proteins contain at least one phenylalanine ...
Yue Weng +3 more
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Modern strategies for C–H functionalization of heteroarenes with alternative coupling partners
Chem, 2021 Summary Heteroarenes containing oxygen, nitrogen, and/or sulfur are important in numerous aspects of chemistry and everyday life. C–H functionalization of heteroarenes represents the fastest and most atom-economical approach for the synthesis of complex ...
Binlin Zhao +2 more
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Accounts of Chemical Research, 2020 Conspectus. The functionalization of unactivated carbon–hydrogen (C–H) bonds is a transformative strategy for the rapid construction of molecular complexity given the ubiquitous presence of C–H bonds in organic molecules.
Qian Shao +4 more
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Diversification of pharmaceutical molecules via late-stage C(sp2)–H functionalization
Green Synthesis and Catalysis, 2023 C–H late-stage functionalization has gradually become a powerful approach for the rapid optimization of lead compounds’ bioactivity. Significant advances in this field have been achieved in the past few years, mainly, the C–H functionalization system in (
Weidong Shang +3 more
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Transition-metal-free electrochemical-induced active C(sp3)-H functionalization
Green Chemistry Letters and Reviews, 2023 Direct C–H bond functionalization is the most effective technique to construct C–X (X = C, N, O, S, etc.), which could simplify the conventional synthesis methods.
Xiaolong Ma +4 more
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Engineered and Artificial Metalloenzymes for Selective C–H Functionalization
Current Opinion in Green and Sustainable Chemistry, 2021 The direct functionalization of C–H bonds constitutes a powerful strategy to construct and diversify organic molecules. However, controlling the chemo- and site-selectivity of this transformation in particularly complex molecular settings represents a ...
Xinkun Ren, R. Fasan
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Strategies to transform remote C(sp3)-H bonds of amino acid derivatives
Tetrahedron Chem, 2022 Amino acids and peptides play an important role in nature as well as in the pharmaceutical industry. Therefore, transformation of amino acids and peptides into their unnatural derivatives via step and atom economical ways is highly demanding. Although, a
Supreeta Sen +2 more
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