Results 41 to 50 of about 123,266 (262)
Stereoselective C−B and C−H Bonds Functionalization of polyBorylated Alkenes
, 2023 Alkenes are fundamental functional groups which feature in various materials and bioactive molecules; however, efficient divergent strategies for their stereodefined synthesis are difficult.
Narendra K., Vaishanv +3 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
, 2022 Cyclic amines are ubiquitous structural motifs found in pharmaceuticals and biologically active natural products, making methods for their elaboration via direct C–H functionalization of considerable synthetic value.
Bo M. , Couture +5 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro +11 more
wiley +1 more source
Visible light-induced direct α C–H functionalization of alcohols
Nature Communications, 2019 Alcohols are very useful building blocks in organic synthesis, however C–H functionaliztion in presence of free –OH groups is highly challenging. Here, the authors report a selective visible light-promoted α-functionalization of free alcohols with ...
Linbin Niu +4 more
doaj +1 more source
Green Synthesis and Catalysis, 2023 Transition-metal-catalyzed C–H bond functionalization has attracted tremendous attention as an increasingly important protocol for the construction of C–C and C–X bonds.
Jian Zhang +5 more
doaj +1 more source
Supporting Survivor‐Centered Care Through Digital Health Integration
Pediatric Blood &Cancer, EarlyView.ABSTRACT Survivors of childhood cancer face barriers to receiving guideline‐based, long‐term follow‐up care. Two digital tools, Passport for Care (PFC) and Cancer SurvivorLink (SurvivorLink), address complementary gaps by enabling tailored survivorship care plan (SCP) generation, updating, storage, and sharing.
Jordan G. Marchak +15 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2023 The importance of functionalized imidazo heterocycles has often been featured in several impactful research both from academia and industry. Herein, we report a direct C-3 acetoxymalonylation of imidazo heterocycles using relay C–H functionalization ...
Deepak Singh +2 more
doaj +1 more source
Transition Metal-Catalyzed Remote C–H Bond Functionalization of Cyclic Amines
SynOpen, 2022 C–H bond functionalization is one of the most effective strategies for the rapid synthesis of cyclic amines containing substituents in the ring, which are core structures of many bioactive molecules. It is, however, much more challenging to perform this
Weijie Chen, Xiaoyu Yang, Xi Cao
doaj +1 more source
Organocatalytic Asymmetric α-C-H Functionalization of Alkyl Amines
, 2023 Catalytic enantioselective α-C–H functionalization of achiral amines could provide an ideal synthetic approach toward chiral amines. The alkyl amines constitute the most diverse and synthetically important class of achiral amines.
Cheng, Cheng +9 more
core +1 more source