Results 71 to 80 of about 31,021,495 (194)
Functional analysis of the sporulation-specific diadenylate cyclase CdaS in Bacillus thuringiensis
Frontiers in Microbiology, 2015 Cyclic di-AMP (c-di-AMP) is a recently discovered bacterial secondary messenger molecule, which is associated with various physiological functions. In Bacillus, the intracellular level and turnover of c-di-AMP is mainly regulated by three diadenylate ...
Cao eZheng +5 more
doaj +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
, 2016 LAUREA MAGISTRALEIl lavoro progettuale elaborato affronta un tema relativamente nuovo all’interno del panorama architettonico contemporaneo, legato alla riqualificazione di estese aree produttive in dismissione.
ZUCCHETTI, JACOPO +1 more
core
Ag85B with c-di-AMP as mucosal adjuvant showed immunotherapeutic effects on persistent Mycobacterium tuberculosis infection in mice [PDF]
Brazilian Journal of Medical and Biological ResearchTuberculosis (TB), caused by Mycobacterium tuberculosis, remains the leading cause of mortality by a single infectious agent in the world. M. tuberculosis infection could also result in clinical chronic infection, known as latent TB infection (LTBI ...
Xuan Liang +12 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau +11 more
wiley +1 more source
Frontiers in Microbiology, 2016 The Gram-positive model organism Bacillus subtilis produces the essential second messenger signaling nucleotide cyclic di-AMP. In B. subtilis and other bacteria, c-di-AMP has been implicated in diverse functions such as control of metabolism, cell ...
Jan eGundlach +4 more
doaj +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Controllo termico predittivo di una camera termovuoto per prove di qualifica spaziali [PDF]
, 2013 LAUREA SPECIALISTICAQuesta tesi nasce dall’esigenza di aumentare l’efficacia e l'efficienza delle leggi di controllo termico della camera termovuoto del Dipartimento di Scienze e Tecnologie Aerospaziali del Politecnico di Milano.
TACCA, STEFANO
core
Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis
Arthritis Care &Research, EarlyView.Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang +21 more
wiley +1 more source
Presence, synthesis, and light-dependence of c-di-AMP in S. elongatus.
, 2018 (A) Predicted CdaA protein topology. (B) Intracellular c-di-AMP measured by LC-MS for WT and cdaA transposon mutant (8S16-L9). Intracellular c-di-AMP concentrations were determined from raw quantities using cell volume (see Materials and Methods).
Susan S. Golden (334364) +11 more
core +1 more source