Results 131 to 140 of about 459,122 (273)
Novel c-di-GMP recognition modes of the mouse innate immune adaptor protein STING. Corrigendum [PDF]
, 2013 Ko‐Hsin Chin +10 more
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Biotechnology Progress, EarlyView.Abstract Induced pluripotent stem cells (iPSCs) offer significant therapeutic potential, but cryopreservation challenges, particularly the reliance on cytotoxic Dimethyl Sulfoxide (Me2SO), hinder their clinical application. This review examines current cryopreservation practices in clinical and preclinical iPSC‐based therapies, highlighting the ...
Michael Dobruskin +2 more
wiley +1 more source
Polyphosphate, cyclic AMP, guanosine tetraphosphate, and c-di-GMP reduce in vitro Lon activity [PDF]
, 2014 Devon O. Osbourne +3 more
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Continuous purification of a parvovirus using two aqueous two‐phase extraction steps
Biotechnology Progress, EarlyView.Abstract Aqueous two‐phase systems (ATPS) are a liquid–liquid extraction method that offers low‐cost, continuous‐adaptable virus purification. A two‐step ATPS using polyethylene glycol (PEG) and sodium citrate that recovered 66% of infectious porcine parvovirus with 2.0 logs of protein removal and 1.0 logs of DNA removal in batch has now been run ...
Natalie M. Nold +11 more
wiley +1 more source
Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities
Cancer Communications, EarlyView.Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan +13 more
wiley +1 more source
Combating cancer immunotherapy resistance: a nano‐medicine perspective
Cancer Communications, EarlyView.Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong +10 more
wiley +1 more source
Plasma Processes and Polymers, Volume 20, Issue 1, January 2023., 2023 In this study, a novel composite based on calcium phosphate ceramic and the plasma‐treated hydrogel is developed. With such a combination it is possible to supplement the excellent bone regenerative properties of calcium phosphates bone grafts with an anticancer agent, that is, the plasma‐treated hydrogel. While being selective toward OS cells in vitro,
Xavi Solé‐Martí +6 more
wiley +1 more source
Estudo de proteínas GGDEF-EAL em vias de sinalização de c-di-GMP em Xanthomonas citri subsp. citri [PDF]
, 2015 Raphael Dias Teixeira
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Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor
Cancer Communications, EarlyView.Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai +6 more
wiley +1 more source