Results 41 to 50 of about 459,122 (273)
The bacterial second messenger c-di-GMP: mechanisms of signalling [PDF]
Cellular Microbiology, 2011 Cyclic-di-GMP (c-di-GMP) regulates many important bacterial processes. Freely diffusible intracellular c-di-GMP is determined by the action of metabolizing enzymes that allow integration of numerous input signals. c-di-GMP specifically regulates multiple cellular processes by binding to diverse target molecules.
Erez Mills +3 more
openaire +3 more sources
Terrein is an inhibitor of quorum sensing and c-di-GMP in Pseudomonas aeruginosa: a connection between quorum sensing and c-di-GMP [PDF]
Scientific Reports, 2018 AbstractTo address the drug-resistance of bacterial pathogens without imposing a selective survival pressure, virulence and biofilms are highly attractive targets. Here, we show that terrein, which was isolated from Aspergillus terreus, reduced virulence factors (elastase, pyocyanin, and rhamnolipid) and biofilm formation via antagonizing quorum ...
Bo-Min Kim +4 more
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mBio, 2021 Because bacterial surface glycans are in direct contact with the environment they can provide essential protective functions during infections or against competing bacteria.
Benjamin Sellner +5 more
semanticscholar +1 more source
Antimicrobial Agents and Chemotherapy, 2021 A decade of research has shown that the molecule c-di-GMP functions as a central second messenger in many bacteria. A high level of c-di-GMP is associated with biofilm formation, whereas a low level of c-di-GMP is associated with a planktonic single-cell
J. B. Andersen +7 more
semanticscholar +1 more source
Impact of edaphoclimatic conditions and crop season on olive oil's fatty acids
Agronomy Journal, Volume 114, Issue 6, Page 3118-3128, November/December 2022., 2022 Abstract The olive tree (Olea europaea L.) fruit oil attracts widespread interest because of its high content of monounsaturated fatty acids. However, a neglected area in the field is the edaphoclimatic factors impact, which is poorly understood. Bearing this in mind, the purpose of this investigation was to evaluate the impact of the edaphoclimatic ...
Touria Lechhab +5 more
wiley +1 more source
Detection of c-di-GMP-Responsive DNA Binding [PDF]
, 2017 Modulation of signal transduction via binding of the secondary messenger molecule cyclic di-GMP to effector proteins is a near universal regulatory schema in bacteria. In particular, direct binding of c-di-GMP to transcriptional regulators has been shown to alter gene expression of a variety of processes.
Jacob R. Chambers, Karin Sauer
openaire +2 more sources
A Multimodal Strategy Used By A Large c-di-GMP Network [PDF]
Journal of Bacteriology, 2017 AbstractThePseudomonas fluorescensgenome encodes for 50+ proteins involved in -di-GMP signaling. Here, we demonstrate that when tested across 188 nutrients, these enzymes and effectors appear capable of impacting biofilm formation. Transcriptional analysis of network members across ∼50 nutrient conditions indicates that altered gene expression can ...
Dahlstrom, Kurt M. +7 more
openaire +4 more sources
mBio, 2022 The second messenger c-di-GMP is important during both stages of the nutrient-regulated biphasic life cycle of Myxococcus xanthus with the formation of predatory swarms in the presence of nutrients and spore-filled fruiting bodies in the absence of ...
Sofya Kuzmich +6 more
semanticscholar +1 more source
Journal of Bacteriology, 2022 Critical bacterial processes, including motility, are influenced by c-di-GMP, which is controlled by environment-responsive synthetic and degradative enzymes.
Prerana Shrestha +4 more
semanticscholar +1 more source
Frontiers in Immunology, 2022 Pertussis, caused by the gram-negative bacterium Bordetella pertussis, is a highly contagious respiratory disease. Intranasal vaccination is an ideal strategy to prevent pertussis, as the nasal mucosa represents the first-line barrier to B.
Wenwen Jiang +8 more
semanticscholar +1 more source