Results 111 to 120 of about 49,818 (236)
Expression of epidermal growth factors and apoptosis markers in pancreatic ductal adenocarcinoma.
Folia Histochemica et Cytobiologica, 2010 <strong>BACKGROUND</strong><br />Epidermal growth factor family members: EGF, EGFR and the c-erbB-2(HER-2/neu) are involved in the growth of pancreatic ductal carcinoma, its invasiveness and metastases.
Jolanta Czyzewska +3 more
doaj +1 more source
Relationship between p53 expression and gastric cancers in cardia and antrum [PDF]
, 2008 Background: The mutations in p53 gene and accumulation of p53 protein are the most common genetic events in gastric carcinomas. The present study was conducted to compare the frequency of p53 gene overexpression in a consecutive series of adenocarcinomas
Amiriani, T. +3 more
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Immunohistochemical localization of c-erbB-2 in human breast carcinomas
Molecular and Cellular Probes, 1987 This study was carried out to assess the utility of antibodies raised to synthetic peptides of the predicted sequence of the c-erbB-2 gene product to identify immunocytochemically those tumours overexpressing this putative transmembrane receptor. Staining with rabbit antiserum 21N gave the best correlation with gene amplification and did not stain the ...
B A, Gusterson +7 more
openaire +2 more sources
Gastric signet‐ring cell carcinoma in a child: A clinical case study
JPGN Reports, Volume 7, Issue 2, Page 285-288, May 2026.Abstract Gastric signet‐ring cell carcinoma (SRCC) is a rare form of gastric cancer characterized by mucus‐rich tumor cells forming a distinctive ring‐like appearance and is exceedingly rare in children, accounting for less than 1% of all childhood malignancies.
Jiaxian Wang +6 more
wiley +1 more source
Cancer Science, Volume 117, Issue 5, Page 1469-1480, May 2026.Early screening for somatic alterations in localized prostate cancer could help predict biochemical recurrence risk and optimize salvage therapy selection. ABSTRACT The clinical significance of comprehensive genomic profiling (CGP) has been established in metastatic castration‐resistant prostate cancer (PC).
Kenji Zennami +7 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 1996 应用单克隆抗体Ｃ－ｅｒｂＢ－２肿瘤蛋白及免疫组化（ＬＳＡＢ）法，对８４例乳腺浸润性导管癌作Ｃ－ｅｒｂＢ－２癌基因蛋白产物表达（简称Ｃ－ｅｒｂＢ－２表达）检测并与随诊资料进行比较分析，结果（１）Ｃ－ｅｒｂＢ－２在本组病例的表达率为５５．９％（４７／８４）。（２）Ｃ－ｅｒｂＢ－２表达与肿瘤的ＴＮＭ分期、复发／远必转移、５ａ生存率无相关性（Ｐ＞０．０５）、而仅与腋淋巴结转移状况和２ａ死亡率有关（Ｐ＜０．００５及Ｐ＜０．０５）。（３）有／无淋巴结转移病例的Ｃ－ｅｒｂＢ－２表达与患者的预后均无关（Ｐ＞０．７５ ...
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European Journal of Histochemistry, 2009 In order to identify the prognostic factors that significantly influence the disease-free survival rate after surgical resection of primary breast cancers, we determined tumour and lymph node grades, and immunohistochemical staining for estrogen and ...
K Horita +6 more
doaj +1 more source
Zhongguo shiyan zhenduanxue, 2012 目的探讨上皮钙黏蛋白（E-cad、β-cat）和C-erbB-2在非小细胞肺癌（NSCLC）中的表达及其相互之间的关系。方法免疫组化SP法检测了41例非小细胞肺癌标本中E-cad、β-cat、C-erbB-2的表达情况。结果 E-cad及β-cat在NSCLC中低表达,并与临床分期、病理分级及淋巴结转移有明显相关性 ...
王凤玲 +3 more
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Prognostic and clinical implications of c-erbB-2 expression in patients with oral cancer: A meta-analysis. [PDF]
Medicine (Baltimore), 2020 Meng Y, Yang P, Ma L.
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 1998 目的: 研究 c -erbB-2, c-erbB-4 原癌基因过度表达与乳腺癌发生及其病理参数的相关关系。方法: 对 122 例乳腺疾病石蜡切块,其 中 80 例乳腺癌, 16 例乳腺纤维腺瘤, 9 例乳腺纤维囊性病, 17 例乳腺癌转移淋巴结均采用免疫组化( LSAB 法)结合计算机图象分析研究原癌 基因产物 c-erbB-2, c-erbB-4的表达情况。结果: c-erbB-2 在乳腺癌中存在过度表达, P
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