Results 121 to 130 of about 49,818 (236)
p53、bcl-2和c-erbB-2在恶性卵巢上皮性肿瘤中的表达及临床意义
Zhongguo shiyan zhenduanxue, 2006 目的检测62例恶性卵巢上皮性肿瘤中p53、bcl-2和c-erbB-2的表达情况以探讨三种基因对恶性卵巢上皮性肿瘤的早期诊断及预后判断的意义。方法采用免疫组织化学方法检测p53b、cl-2 and c-erbB-2在恶性卵巢上皮性肿瘤中的表达及其与组织学分类,临床分期,腹水,淋巴结转移预后的关系。结果恶性卵巢上皮性肿瘤在p53、bcl-2 and c-erbB-2的表达阳性率分别52.23%,62.90%和45.16%与卵巢瘤组和正常组之间比较差异有显著性 ...
许天敏, 崔满华, 林杨, 何凯
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Zhongguo shiyan zhenduanxue, 2002 目的 探讨幽门螺杆菌感染与胃癌P53 、C erbB - 2的关系。方法 应用Warthin -Starry染色法检测幽门螺杆菌 ,免疫酶组化SP法检测P53 、C -erbB - 2基因蛋白。结果 Hp感染率在胃癌和癌前病变组中均高于对照组 ,而前两组差异无显著性 ,Hp感染与C erbB 2过度表达有关。P53 仅在胃癌组织中表达 ,Hp感染者与P53 过度表达有关 （P
房学东, 杨作森, 冯涛
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São Paulo Medical JournalCONTEXT AND OBJECTIVE: Breast cancer is thought to derive from progressively aberrant, non-invasive breast lesions, but it is not known exactly how invasive breast cancer develops from these lesions.
Marcus Vinicius Martins de Menezes +7 more
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c-erbB-2 expression and nuclear pleomorphism in canine mammary tumors
Brazilian Journal of Medical and Biological Research, 2004 The objective of the present investigation was to study the expression of c-erbB-2 and MIB-1 and try to associate them with morphological features of the cell such as nuclear pleomorphism, mitotic count and histological grade in a series of 70 canine ...
Dutra A.P. +3 more
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New treatments for breast cancer: Breakthroughs for patient care or just steps in the right direction? [PDF]
, 2017 Three areas of clinical research in breast cancer treatment led to news breaking presentations at the American Society of Clinical Oncology (ASCO) meeting, 1998, in Los Angeles.
Castiglione-Gertsch, M. +3 more
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Results in EngineeringThis research work presents an innovative charge-modulated hybrid dielectric organic thin-film transistor (CM-HD OTFT) biosensor designed for the early detection of the breast cancer biomarker C-erbB-2 in saliva and serum samples. By incorporating a dual-
L. Prasanthi +6 more
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胃癌p53、c-erbB-2、p21、nm23基因表达的分布特点及其临床意义
Zhongguo shiyan zhenduanxue, 2005 目的为探讨手术切除胃癌组织p53、c-erbB-2、p21、nm23联合基因产物表达检测对胃癌诊断治疗及预后判断的价值。方法应用免疫组化技术检测了手术切除胃癌组织p53c、-erbB-2、p21、nm23基因产物表达。结果p53蛋白表达阳性率为36.4%46.7%,c-erbB-2为33.3%56.8%,p21为35.1%56.7%,nm23为30.0%70.5%。在非胃癌组织中（胃,十二指肠溃疡,胃息肉,重度不典型增生）未见c-erbB-2、p21、nm23基因表达。p53c、-erbB-2 ...
陈永胜 +4 more
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Zhongguo shiyan zhenduanxue, 2009 目的探讨C-erbB-2和葡萄糖转运蛋白1（Glut-1）在不典型增生子宫内膜和子宫内膜腺癌中的表达特点及其相互关系。方法应用免疫组织化学方法检测Glut-1、C-erbB-2在30例正常增生期子宫内膜、32例不典型增生子宫内膜和35例子宫内膜腺癌中的表达,并结合临床资料进行分析。结果Glut-1、C-erbB-2在各组中的阳性表达率增生期子宫内膜均为0,不典型增生组分别为46.9%和59.4%,子宫内膜腺癌组82.9%,74.3%;二者在各试验组间均有显著差异 ...
张颖, 陈海玲
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Estrogen dependent expression of the receptor tyrosine kinase axl in normal and malignant human breast [PDF]
, 2017 Summary Background: Axl, a member of a family of receptor tyrosine kinases characterized by an extracellular domain resembling cell adhesion molecules and an intracellular conserved tyrosine kinase domain has been reported to induce cell proliferation ...
Altermatt, H. J. +5 more
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